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001-es BibID:	BIBFORM112718
035-os BibID:	(WOS)000426432400021 (Scopus)85041390859
Első szerző:	Harris, C.
Cím:	Optimising the measurement of bruises in children across conventional and cross polarized images using segmentation analysis techniques in Image J, Photoshop and circle diameter measurements / C. Harris, A. Alcock, L. Trefan, D. Nuttall, S. T. Evans, S. Maguire, A. M. Kemp
Dátum:	2018
ISSN:	1752-928X 1532-2009
Megjegyzések:	Background: Bruising is a common abusive injury in children, and it is standard practice to image and measure them, yet there is no current standard for measuring bruise size consistently. We aim to identify the optimal method of measuring photographic images of bruises, including computerised measurement techniques. Methods: 24 children aged<11 years (mean age of 6.9, range 2.5?10 years) with a bruise were recruited from the community. Demographics and bruise details were recorded. Each bruise was measured in vivo using a paper measuring tape. Standardised conventional and cross polarized digital images were obtained. The diameter of bruise images were measured by three computer aided measurement techniques: Image J (segmentation with Simple Interactive Object Extraction (maximum Feret diameter), ♭Circular Selection Tool' (Circle diameter), & the Photoshop ♭ruler' software (Photoshop diameter)). Inter and intra-observer effects were determined by two individuals repeating 11 electronic measurements, and relevant Intraclass Correlation Coefficient's (ICC's) were used to establish reliability. Spearman's rank correlation was used to compare in vivo with computerised measurements; a comparison of measurement techniques across imaging modalities was conducted using Kolmogorov-Smirnov tests. Significance was set at p < 0.05 for all tests. Results: Images were available for 38 bruises in vivo, with 48 bruises visible on cross polarized imaging and 46 on conventional imaging (some bruises interpreted as being single in vivo appeared to be multiple in digital images). Correlation coefficients were>0.5 for all techniques, with maximum Feret diameter and maximum Photoshop diameter on conventional images having the strongest correlation with in vivo measurements. There were significant differences between in vivo and computer-aided measurements, but none between different computer-aided measurement techniques. Overall, computer aided measurements appeared larger than in vivo. Inter- and intra-observer agreement was high for all maximum diameter measurements (ICC's > 0.7). Conclusions: Whilst there are minimal differences between measurements of images obtained, the most consistent results were obtained when conventional images, segmented by Image J Software, were measured with a Feret diameter. This is therefore proposed as a standard for future research, and forensic practice, with the proviso that all computer aided measurements appear larger than in vivo.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk forensic
Megjelenés:	Journal of Forensic and Legal Medicine. - 54 (2018), p. 114-120. -
További szerzők:	Alcock, Amy Trefán László (1969-) (biostatisztikus, bioinformatikus) Nuttall, D. Evans, S. T. Maguire, Sabine Kemp, Alison M.
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM112717
035-os BibID:	(WOS)000442687300007 (Scopus)85051107653
Első szerző:	Trefán László (biostatisztikus, bioinformatikus)
Cím:	A comparison of four different imaging modalities - Conventional, cross polarized, infra-red and ultra-violet in the assessment of childhood bruising / L. Trefan, C. Harris, S. Evans, D. Nuttall, S. Maguire, A. M. Kemp
Dátum:	2018
ISSN:	1752-928X 1532-2009
Megjegyzések:	Background: It is standard practice to image concerning bruises in children. We aim to compare the clarity and measurements of bruises using cross polarized, infra-red (IR) and ultra-violet (UV) images to conventional images. Methods: Children aged<11 years with incidental bruising were recruited. Demographics, skin and bruise details were recorded. Bruises were imaged by standard protocols in conventional, cross-polarized, IR and UV lights. Bruises were assessed in vivo for contrast, uniformity and diffuseness, and these characteristics were then compared across image modalities. Color images (conventional, cross polarized) were segmented and measured by ImageJ. Bruises of grey scale images (IR, UV) were measured by a ♭plug in' of ImageJ. The maximum and minimum Feret's diameter, area and aspect ratio, were determined. Comparison of measurements across imaging modalities was conducted using Wilcoxon rank sum tests and modified Bland-Altman graphs. Significance was set at p < 0.05. Results: Twenty five children had 39 bruises. Bruises that were of low contrast, i.e. difficult to distinguish from surrounding skin, were also more diffuse, and less uniformity in vivo. Low contrast bruises were best seen on conventional and cross-polarized images and less distinctive on IR and UV images. Of the 19 bruises visible in all modalities, the only significant difference was maximum and minimum Feret's diameters and area were smaller on IR compared to conventional images. Aspect ratios were not affected by the modality. Conclusions: Conventional and cross-polarized imaging provides the most consistent bruise measurement, particularly in bruises that are not easily distinguished from surrounding skin visually.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk forensic
Megjelenés:	Journal of Forensic and Legal Medicine. - 59 (2018), p. 30-35. -
További szerzők:	Harris, C. Evans, S. Nuttall, D. Maguire, Sabine Kemp, Alison M.
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM112976
035-os BibID:	(Scopus)85008707977 (WOS)000392644800006
Első szerző:	Warner, Christopher
Cím:	A study of radiological features of healing in long bone fractures among infants less than a year / Christopher Warner, Sabine Maguire, Laszlo Trefan, Angie Miller, Jason Weinman, Michael Fadell
Dátum:	2017
ISSN:	0364-2348
Megjegyzések:	Purpose To create a timetable for dating long bone fractures in infants aged less than 1 year using previously defined radiographic signs of fracture healing. Materials and methods A retrospective cross-sectional time series of long bone fractures in infants aged less than 1 year was conducted from 2006 to 2013. After exclusion criteria were applied 59 digital image series were available for review from 40 infants. Utilizing published criteria for dating fractures, the presence or absence of four pre-defined features of healing was scored: periosteal reaction, callus, bridging, and remodeling. Three radiologists independently scored radiographs with a 3-point scale, marking each feature as present, absent, or equivocal. The times in days when features were first seen, peaked (feature agreed present in >40% of images), and last seen were noted. Statistical analysis using free marginal kappa was conducted. Results The level of agreement among the three radiologists was high (0.64?0.85). The sequence in which the features were seen was: periosteal reaction range 7?130 (present in the majority of cases between 9 and 49 days); callus range 9?130 (present in the majority of cases between days 9?26); bridging range 15?130 (seen in the majority of cases between 15 and 67 days); remodeling range 51?247 days. Conclusion This study provides a timetable of radiological features of long bone healing among young infants for the first time. Dating of incomplete long bone fractures is challenging, beyond the presence of periosteal reaction, but a consistent sequence of changes is present in complete fractures.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Skeletal Radiology. - 46 : 3 (2017), p. 333-341. -
További szerzők:	Maguire, Sabine Trefán László (1969-) (biostatisztikus, bioinformatikus) Miller, Angie Weinman, Jason Fadell, Michael
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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