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001-es BibID:BIBFORM045987
Első szerző:Gregson, Barbara A.
Cím:International Variations in Surgical Practice for Spontaneous Intracerebral Hemorrhage / Barbara A. Gregson, A. David Mendelow, STICH Investigators
Dátum:2003
ISSN:0039-2499 1524-4628
Megjegyzések:Background and Purpose -Spontaneous intracerebral hemorrhage is a major cause of death and disability, yet there is no convincing evidence of the benefit of any medical treatment and the role of surgery remains controversial. The international randomized Surgical Trial in Intracerebral Hemorrhage (STICH) provided an opportunity to assess the role of surgery within the centers taking part. Methods -Screening logs were completed to record details of all patients assessed by the department, whether they were included in the trial, the reasons if they were not included, and whether they underwent surgery. Results -Logs were returned by 42 centers and cover 704 months. They include details on 1578 patients with characteristics comparable to STICH inclusion criteria. Neurosurgeons were more likely to express clinical certainty about treatment for older patients, patients with a higher Glasgow Coma Score scale, and patients in whom the hematoma was located on the right or in the basal ganglia or thalamus. Patients for whom the neurosurgeon was certain about treatment were more likely to have the hematoma removed if they were younger (62 versus 68 years of age), had a lower Glasgow Coma Scale score (10 versus 13), and had a lobar hematoma (49% versus 40%). The operation rate varied between 74% in Lithuania and 2% in Hungary. Conclusions -The difference in operation rates could not be explained by differences in patient characteristics alone. This finding demonstrates the need for further evidence to ensure that treatment for intracerebral hemorrhage is not governed by local custom. ( Stroke . 2003;34:2593-2598.)
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
intracranial hemorrhages
multicenter studies
physician's practice patterns
surgery
Megjelenés:Stroke. - 34 : 11 (2003), p. 2593-2598. -
További szerzők:Mendelow, A. David Szabó Sándor (1957-) (idegsebész) Bereczki Dániel (1960-) (neurológus) STICH Investigators
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:BIBFORM040683
Első szerző:Szabó Sándor (idegsebész)
Cím:Cerebrovascular reserve capacity many years after vasospasm due to aneurysmal subarachnoid hemorrhage : a transcranial Doppler study with acetazolamide test / Szabó, S., Rishi, N. S., Novák, L., Rózsa, L., Ficzere, A.
Dátum:1997
ISSN:0039-2499
Megjegyzések:BACKGROUND AND PURPOSE: Vasospasm in aneurysmal subarachnoid hemorrhage results in proliferative vasculopathy. Systemic hypertension also causes vascular hypertrophy. Both of these histological changes can lead to rigidity of the cerebrovascular system, reducing its autoregulatory capacity. METHODS: Blood flow velocity (BFV) in the middle cerebral artery at rest and cerebrovascular reserve capacity (CVRC) (percent rise in BFV after acetazolamide stimulation) measured by means of transcranial Doppler sonography were studied many years after aneurysmal subarachnoid hemorrhage in patients with proven cerebral vasospasm (mean BFV > 160 cm/s). The BFV under resting conditions and the CVRC values of the ipsilateral and the contralateral hemispheres were measured in 29 patients (mean age, 43 years; mean follow-up, 4.6 years) and compared with those of control subjects. RESULTS: Persistent high BFV (> 120 cm/s) was found in three patients in the peripheral branch of the ipsilateral middle cerebral artery. In the main trunks of the arteries of the anterior circle of Willis, BFV was normal in all cases. CVRC was normal in all patients (ipsilateral, 52 +/- 21%; contralateral, 56 +/- 17%); values did not differ significantly from each other or from the control value (45 +/- 18%). The higher value of CVRC on the contralateral side was found to be statistically significant in selected groups (hypertensive patients and patients with residual infarct on late CT). CONCLUSIONS: Proliferative vasculopathy developed at the time of vasospasm must have resolved and did not reduce late vasoreactivity. Comorbidity with hypertension also did not seem to influence the late vasoreactivity toward normalization.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Stroke. - 28 : 12 (1997), p. 2479-2482. -
További szerzők:Rishi, N. Sheth Novák László (1964-) (idegsebész) Rózsa László (1946-) (idegsebész) Ficzere Andrea (1967-) (neurológus)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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