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1.

001-es BibID:BIBFORM087867
035-os BibID:(Scopus)85091004594 (WOS)000565252800001
Első szerző:Fülesdi Béla (aneszteziológus)
Cím:Correlation between calcium, water contents and ultrasonographic appearance of atherosclerotic lesions of carotid artery lesions / Béla Fülesdi, Szabolcs Farkas, Zoltán Gyöngyösi, Péter Siró, Dániel Bereczki, József Bacsó, László Csiba
Dátum:2020
ISSN:2081-3856 2081-6936
Megjegyzések:Background We tested the hypothesis whether there is a correlation between the echogenicity and calcium and water contents of carotid plaques. Patients and methods Ninety carotid befurcations from 45 deceased patients were removed during autopsy. Thirty-four plaques were categorized as homogenous echolucent (HEL), homogenous echogenic (HEG) and heterogenous (HE) plaques based on premortem B-mode image. Water content was expressed in % of wet weight. Ca was determined by proton-induced X-ray emission and expressed in ppm. Relative optical density of the B-mode images was analyzed offline using a computer program. Results HEL plaques had lower Ca content (medians and IQRs: 6,145 [4,465?6,536?ppm]) compared to HEG (74,100 [15,300?1,44,500?ppm]), P ? 0.001). HE plaques showed an intermediate calcium content (7,310 [4,840?9,920?ppm]) that was statistically not different from echolucent plaques. Water content of HEG plaques was statistically not different from HEL and HE (HEG:53.5 [35.5?64%], HEL: 73.5 [69.7?78.5%], HE: 70.6 [67.4?73.9%]). HEG plaques had the highest relative optical densities (196 [188?217%]). HEL and HE had similar relative optical densities (HEL: 176 [164?187%], HE: 164 [144?188%], respectively). A significant positive correlation was found between the Ca content and relative optical density of plaques. Conclusions Echogenicity of carotid plaques increases along with their calcium content. Water content may be an important factor in differentiation of different plaques.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Ca and water contents
carotid plaque
B-mode ultrasound
ultrasonic tissue characterisation
Megjelenés:Translational Neuroscience. - 11 : 1 (2020), p. 269-276. -
További szerzők:Farkas Szabolcs (1983-) (orvos) Gyöngyösi Zoltán (1977-) (aneszteziológus) Siró Péter (1973-) (neurológus, aneszteziológus, intenzív terápiás szakorvos) Bereczki Dániel (1960-) (neurológus) Bacsó József Csiba László (1952-) (neurológus, pszichiáter)
Pályázati támogatás:2017-1.2.1-NKP-2017-00002
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Intézményi repozitóriumban (DEA) tárolt változat
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2.

001-es BibID:BIBFORM113230
035-os BibID:(cikkazonosító)20220293 (scopus)85164812640
Első szerző:Gyöngyösi Zoltán (1977-)
Cím:Incomplete circle of Willis as a risk factor for intraoperative ischemic events during carotid endarterectomies performed under regional anesthesia : A prospective case-series / Gyöngyösi Zoltán, Belán Ivett, Nagy Edit, Fülesdi Zsófia, Farkas Orsolya, Végh Tamás, Hoksbergen Arjan Willem, Fülesdi Béla
Dátum:2023
ISSN:2081-3856
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Translational Neuroscience. - 14 : 1 (2023), p. 1-8. -
További szerzők:Belán Ivett Nagy Edit Fülesdi Zsófia (1990-) (radiológus) Farkas Orsolya Végh Tamás (1975-) (aneszteziológus, intenzív terápiás szakorvos) Hoksbergen, Arjan W. J. Fülesdi Béla (1961-) (aneszteziológus)
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Intézményi repozitóriumban (DEA) tárolt változat
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3.

001-es BibID:BIBFORM106083
Első szerző:Gyöngyösi Zoltán (1977-)
Cím:The value of transcranial Doppler monitoring of cerebral blood flow changes during carotid endarterectomy performed under regional anesthesia : A case series / Gyöngyösi Zoltán, Farkas Orsolya, Papp Lóránd, Bodnár Fruzsina, Végh Tamás, Fülesdi Béla
Dátum:2022
ISSN:2081-3856 2081-6936
Megjegyzések:Abstract: Recent evidence suggests no difference between patient outcomes when carotid endarterectomies (CEAs) are performed under general or regional anesthesia. However, for detecting the need for a shunt, general anesthesia has the drawback of monitoring needs in the intraoperative setting. In the present study, we attempted to perform intraoperative transcranial Doppler (TCD) monitoring for CEAs performed under intermediate plexus block to describe cerebral hemodynamic changes during different phases of the procedure. Patients and methods ? Patients with unilateral hemodynamically significant carotid stenosis scheduled for elective CEAs were included. Ultrasound-guided intermediate plexus block was used for regional anesthesia. TCD monitoring of the middle cerebral artery mean blood flow velocity (MCAV) was performed throughout the procedure. MCAVs were offline analyzed during different phases of CEA: (1) resting state, before regional block, (2) after block, before incision, (3) before cross-clamp, (4) after cross-clamp, (5) 5 min after cross-clamp, (6) 10 min after cross-clamp, (7) after declamping, and (8) during the postoperative period (4?6 h). Results ? Shunt insertion based on the deterioration of neurological symptoms after cross-clamping was necessary for 11/66 patients (16.6%). In these symptomatic patients, the ipsilateral percent decrease of the MCAV was more than 70% in 8 out of 11 cases (72.7%). In asymptomatic patients, without shunt insertion, the average decrease of MCAV was less than 50%. Conclusions ? Neurological symptoms referring to cerebral ischemia may be superior to TCD monitoring of cerebral blood flow for detecting the necessity of a shunt. Regional anesthesia enables reliable, symptom-based monitoring of CEAs.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
carotid endarterectomy
regional anesthesia
transcranial Doppler monitoring
Megjelenés:Translational Neuroscience. - 13 : 1 (2022), p. 476-482. -
További szerzők:Farkas Orsolya Papp Lóránd Bodnár Fruzsina (1978-) (orvos) Végh Tamás (1975-) (aneszteziológus, intenzív terápiás szakorvos) Fülesdi Béla (1961-) (aneszteziológus)
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Intézményi repozitóriumban (DEA) tárolt változat
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4.

001-es BibID:BIBFORM105018
035-os BibID:(WOS)000879996500001 (Scopus)85142129652
Első szerző:Orosz László (sebész)
Cím:Assessment of malformations, variations and diameters of vessels forming the circle of Willis : An autopsy study in a non-cerebrovascular cohort / Orosz László, Gyöngyösi Zoltán, Susán Zsolt, Siró Péter, Hoksbergen Arjan Willem, Csiba László, Fülesdi Béla
Dátum:2022
ISSN:2081-3856 2081-6936
Megjegyzések:Background a purpose The collateral capacity of the circle of Willis (CoW) may play an important role in the development of ischemic strokes. The occurrence of classical polygon shows wide geographical variations and morphological data on diameters of the Willisian collaterals are scarce. We aimed to assess CoW variations and vessel diameters in a Central European cohort. Subjects and methods CoWs were removed during routine autopsy. The morphological pattern of the circles was recorded. The prepared circles were then put between two glass plates and tightly compressed. The length of the vessels and half of the circumference were measured under a light microscope enabling measurement with an approximation of 0.1?mm. Vessel diameters were calculated from vessel circumference. Results A total of 110 circles were analysed. Incomplete circles (missing one or two segments of CoW) were found in 25 cases (22.7%). Any forms of anatomical variations were detected in 14 cases (12.7%). When applying the <1?mm diameter threshold for analysis, 36 anterior communicating arteries (32.7%), 53 right posterior communicating arteries (48.2%), 73 left posterior communicating arteries (66.4%) and 18 posterior communicating arteries (16.3%) on both the sides were considered hypoplastic. Conclusions In patients without stroke in their history, complete CoW may be present in >60% of the cases. Our diameter data may serve as reference values for the Central-European population.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Translational Neuroscience. - 13 : 1 (2022), p. 398-406. -
További szerzők:Gyöngyösi Zoltán (1977-) (aneszteziológus) Susán Zsolt (1983-) (sebész) Siró Péter (1973-) (neurológus, aneszteziológus, intenzív terápiás szakorvos) Hoksbergen, Arjan W. J. Csiba László (1952-) (neurológus, pszichiáter) Fülesdi Béla (1961-) (aneszteziológus)
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Intézményi repozitóriumban (DEA) tárolt változat
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5.

001-es BibID:BIBFORM117820
Első szerző:Simon Éva (aneszteziológus)
Cím:Preoperatively administered single dose of dexketoprofen decreases pain intensity on the first 5 days after craniotomy : a single-centre placebo-controlled, randomized trial / Éva Simon, Csaba Csipkés, Dániel Andráskó, Veronika Kovács, Zoltán Szabó-Maák, Béla Tankó, Gyula Buchholcz, Béla Fülesdi, Csilla Molnár
Dátum:2023
ISSN:2081-3856 2081-6936
Megjegyzések:Background and purpose ? Headache attributed to craniotomy is an underestimated and under-treated condition. Previous studies confirmed the efficacy of preemptive analgesia with non-steroidal anti-inflammatory agents. The aim of the present work was to test the hypothesis of whether a single preoperatively administered dose of dexketoprofen (DEX) has the potency to decrease postcraniotomy headache (PCH) as compared to placebo (PL). Patients and methods ? This is a single-centre, randomized, PL-controlled trial comparing the effect of a single oral dose of 25 mg DEX to PL on the intensity of PCH. Patients undergoing craniotomy were randomly allocated to DEX and PL groups. Patients rated their actual and worst daily pain using visual analogue scale (VAS) scores during intrahospital treatment (0?5 days) and 30 and 90 days postoperatively. Results ? Two hundred patientswere included.DEX decreased the worst daily pain intensity in the first 24 h only; the 5- days cumulative score of actual pain was 9.7 ? 7.9 cm for the DEX group and 12.6 ? 10.5 cm for the PL group, respectively (p = 0.03). This difference disappeared in the late, 30-, and 90-day follow-up period. No differences in VAS scores could be detected in supra- and infratentorial cases among the DEX and PL groups. Conclusions ? A single preoperative dose of 25 mg of DEX slightly decreases the intensity of PCH in the first 5 days after craniotomy but it does not have an effect on chronic headaches and postoperative analgesic requirements.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
postcraniotomy headache, preemptive analgesia, dexketoprofen
Megjelenés:Translational Neuroscience. - 14 : 1 (2023), p. 1-8. -
További szerzők:Csipkés Csaba (1994-) (aneszteziológus rezidens) Andráskó Dániel (1994-) (ANESZTEZIOLÓGUS REZIDENS) Kovács Veronika (1991-) (aneszteziológus) Szabó-Maák Zoltán (1984-) (aneszteziológus, intenzív terápiás szakorvos) Tankó Béla (1972-) (aneszteziológus) Buchholcz Gyula (1961-) (aneszteziológus) Fülesdi Béla (1961-) (aneszteziológus) Molnár Csilla (1962-) (aneszteziológus)
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Intézményi repozitóriumban (DEA) tárolt változat
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