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001-es BibID:BIBFORM020312
Első szerző:Módis László (szemész szakorvos, kontaktológus)
Cím:Dry eye diagnosis and management / Módis László, Szalai Eszter
Dátum:2011
ISSN:1746-9899
Megjegyzések:Dry eye disease is a very common multifactorial disease of the lacrimal functional unit that results in tear film instability, hyperosmolarity, chronic irritation and inflammation of the ocular surface. Diagnostic tools have been developing rapidly, however, both classic dry eye tests (Schirmer I test, fluorescein staining of the surface epithelium and tear film break-up time) and noninvasive imaging techniques are essential for an exact diagnosis. The management of dry eye syndrome can be either conservative or invasive based on the severity of the disease. The basic aim of treatment is to improve quality of life and reduce subjective complaints and objective ocular surface alterations in dry eye patients. The first line of treatment is tear substitution with artificial tear drops, gels and ointments. In moderate cases preservative-free tear supplementation, topical anti-inflammatory therapy and retinol treatment is recommended. Temporary or permanent punctal plug occlusion, therapeutic contact lenses or moisture chamber use constitute other options. In severe cases the application of topical autologous serum, systemic anti-inflammatory therapy, androgen substitution, secretagogues and surgical intervention can be effective. In the future, noninvasive diagnostic tools and instruments such as screening methods are likely to be developed. In addition, causal therapy of the dry eye will play a greater role, including cyclosporine therapy, secretion stimulation, growth factor-containing artificial tears, as well as secratogogues, immunomodulants and androgenic complexes for severe forms of the disease.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Expert Review of Ophthalmology. - 6 : 1 (2011), p. 67-79. -
További szerzők:Szalai Eszter (1984-) (orvos)
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