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001-es BibID:	BIBFORM046724
Első szerző:	Ambrus Edit
Cím:	Agydaganatok természetének vizsgálata nukleáris medicinai módszerekkel = Evaluation of the nature of brain tumors using methods of nuclear medicine / Ambrus Edit, Kuncz Ádám, Jánoki Győző, Vörös Erika, Szakáll Szabolcs, Balkay László, Emri Miklós, Trón Lajos, Bodosi Mihály, Csernay László, Pávics László
Dátum:	1999
Megjegyzések:	FDG-PET studies permit an assessment of the degree of brain tumour malignancy and detection of tumour recurrence. MIBI-SPECT also affords promising results in this respect. In this work, the diagnostic value of MIBI-SPECT was compared with that of FDG-PET for the determination of primary brain tumours malignancy and the detection of recurrent brain tumours. SPECT and PET examination were carried out within a week in 14 patients (12 males, mean age: 40 years, range 16-61 years) with brain tumours. Seven patients had a primary tumour, and in a further 7 MRI or the clinical signs and symptoms let to a suspicion of tumour recurrence. All tumours were verified histologically to be gliomas of grades I-IV. The SPECT and PET images were analysed visually and semiquantitatively. In 3 of the investigated 7 primary glioma patients, there was a visibly enhanced MIBI-positive cases, only one had an increased FDG uptake. In 4 of the 7 tumour recurrence cases, either the MIBI or the FDG uptake was visibly increased. All of these were histologically high-grade gliomas. In the remaining low grade tumours (primary of recurrent), neither MIBI nor FDG revealed a pathologically increased uptake. The intensity of radiopharmaceutical uptake at the site of the tumours was visually and semiquantitatively higher for MIBI that for FDG. It is concluded that MIBI-SPECT is a valuable and simple tool for evaluation of the biological characteristics of brain tumours, showing increased uptake of MIBI according to the malignancy and tumour recurrence of brain tumours.újratöltve - BIBFORM031856
Tárgyszavak:	Orvostudományok Klinikai orvostudományok magyar nyelvű folyóiratközlemény hazai lapban
Megjelenés:	Orvosi Hetilap. - 140 : 36 (1999), p. 1979-1983. -
További szerzők:	Kuncz Ádám Jánoki Győző Vörös Erika Szakáll Szabolcs (1970-) jr. Balkay László (1963-) (biofizikus) Emri Miklós (1962-) (fizikus) Trón Lajos (1941-) (biofizikus) Bodosi Mihály Csernay László (Szeged) Pávics László (Szeged)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM045998
Első szerző:	Papos Miklós (Szeged)
Cím:	Az FDG-PET-vizsgálat értéke a pancreascarcinoma diagnosztikájában = The role of FDG-PET scan in the diagnosis of pancreatic carcinoma / Papós Miklós, Takács Tamás, Pávics László, Farkas Gyula, Ambrus Edit, Szakáll Szabolcs jr., Lonovics János, Csernay László, Trón Lajos
Dátum:	2002
Megjegyzések:	In 22 patients with focal pancreatic lesions, the values of different diagnostic modalities were analysed for the evaluation of malignancy. The CA 19-9 level was elevated in 4/5 malignant cases (sensitivity: 80 per cent) and in 4/15 of benign cases specificity: 73 per cent). Hypodensity/hypoechogeneity was considered to be the characteristic sign of malignancy during CT/ultrasound (sensitivity: 100 per cent, specificity: 50 per cent / 47 per cent). ERCP was found to be specific but not sensitive enough and the rate of unsuccessful investigations was relatively high (4/22). The diagnostic value of FDG-PET was found to be superior to other diagnostic modalities (sensitivity 100 per cent, specificity 88 per cent). In cases with focal pancreatic hypoechogenic/hypodense lesions detected by CT or US in suspicion of malignancy, the FDG-PET should be the next step in the diagnostic strategy.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok magyar nyelvű folyóiratközlemény hazai lapban
Megjelenés:	Orvosi Hetilap. - 143 : 21 Suppl. 3 (2002), p. 1283-1286. -
További szerzők:	Takács Tamás (Szeged) Pávics László (Szeged) Farkas Gyula Ambrus Edit Szakáll Szabolcs (1970-) jr. Lonovics János (Szeged) Csernay László (Szeged) Trón Lajos (1941-) (biofizikus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM031233
035-os BibID:	PMID:11852308
Első szerző:	Papos Miklós (Szeged)
Cím:	The possible role of F-18 FDG positron emission tomography in the differential diagnosis of focal pancreatic lesions / Papós Miklós, Takács Tamás, Trón Lajos, Farkas Gyula, Ambrus Edit, Szakáll Szabolcs, Lonovics János, Csernay László, Pávics László
Dátum:	2002
ISSN:	0363-9762
Megjegyzések:	To compare the diagnostic values of different methods for the differentiation of malignant from benign pancreatic lesions. METHODS: In 22 patients with focal pancreatic lesions, the carbohydrate antigen (CA) 19-9 level was measured; abdominal ultrasound (US), computed tomography (CT), endoscopic retrograde cholangiopancreatography (ERCP), and F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) were performed; and the value of these methods were analyzed for their use in cancer diagnosis. RESULTS: Malignant lesions were identified in six patients and verified by surgery or clinical follow-up. The CA 19-9 level was elevated in four of the five patients examined (sensitivity, 80%). In all six cases, US and CT revealed hypoechogenic and hypodense areas (sensitivity, 100%). In one patient, ERCP was unsuccessful but yielded true-positive results in three others (sensitivity, 60%). The sensitivity of FDG PET was 100%. Sixteen focal cases of pancreatic disease proved to be benign. The CA 19-9 level was elevated in four of them (specificity, 73%). Hypoechogenic and hypodense areas were evident on US and CT in eight patients. The specificity of CT was 50% (8 of 16 cases). The specificity of US was 47% (7 of 15 cases). The specificity of successful ERCP was 92%. Fourteen negative FDG-PET results were truly negative. In two patients, however, the PET findings proved to be falsely positive (specificity, 88%). CONCLUSIONS: FDG-PET is an effective tool to differentiate malignant from benign focal pancreatic lesions. In persons with focal pancreatic hypoechogenic or hypodense lesions detected by CT or US and an elevated CA 19-9 level, FDG PET should be the next step in the diagnostic strategy.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban egyetemen (Magyarországon) készült közlemény
Megjelenés:	Clinical Nuclear Medicine. - 27 : 3 (2002), p. 197-201. -
További szerzők:	Takács Tamás (Szeged) Farkas Gyula Ambrus Edit Szakáll Szabolcs (1970-) jr. Lonovics János (Szeged) Csernay László (Szeged) Pávics László (Szeged) Trón Lajos (1941-) (biofizikus)
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