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1.
001-es BibID:
BIBFORM090883
Első szerző:
Papp Zoltán (kardiológus, élettanász)
Cím:
Levosimendan Efficacy and Safety : 20 Years of SIMDAX in Clinical Use / Papp Zoltán, Agostoni Piergiuseppe, Alvarez Julian, Bettex Dominique, Bouchez Stefan, Brito Dulce, Černý Vladimir, Comin-Colet Josep, Crespo-Leiro Marisa G., Delgado Juan F., Édes Istvan, Eremenko Alexander A., Farmakis Dimitrios, Fedele Francesco, Fonseca Cândida, Fruhwald Sonja, Girardis Massimo, Guarracino Fabio, Harjola Veli-Pekka, Heringlake Matthias, Herpain Antoine, Heunks Leo M. A., Husebye Trygve, Ivancan Višnja, Karason Kristjan, Kaul Sundeep, Kivikko Matti, Kubica Janek, Masip Josep, Matskeplishvili Simon, Mebazaa Alexandre, Nieminen Markku S., Oliva Fabrizio, Papp Julius-Gyula, Parissis John, Parkhomenko Alexander, Põder Pentti, Pölzl Gerhard, Reinecke Alexander, Ricksten Sven-Erik, Riha Hynek, Rudiger Alain, Sarapohja Toni, Schwinger Robert H. G., Toller Wolfgang, Tritapepe Luigi, Tschöpe Carsten, Wikström Gerhard, von Lewinski Dirk, Vrtovec Bojan, Pollesello Piero
Dátum:
2020
ISSN:
0160-2446
Megjegyzések:
Levosimendan was first approved for clinical use in 2000, when authorization was granted by Swedish regulatory authorities for the hemodynamic stabilization of patients with acutely decompensated chronic heart failure (HF). In the ensuing 20 years, this distinctive inodilator, which enhances cardiac contractility through calcium sensitization and promotes vasodilatation through the opening of adenosine triphosphate-dependent potassium channels on vascular smooth muscle cells, has been approved in more than 60 jurisdictions, including most of the countries of the European Union and Latin America. Areas of clinical application have expanded considerably and now include cardiogenic shock, takotsubo cardiomyopathy, advanced HF, right ventricular failure, pulmonary hypertension, cardiac surgery, critical care, and emergency medicine. Levosimendan is currently in active clinical evaluation in the United States. Levosimendan in IV formulation is being used as a research tool in the exploration of a wide range of cardiac and noncardiac disease states. A levosimendan oral form is at present under evaluation in the management of amyotrophic lateral sclerosis. To mark the 20 years since the advent of levosimendan in clinical use, 51 experts from 23 European countries (Austria, Belgium, Croatia, Cyprus, Czech Republic, Estonia, Finland, France, Germany, Greece, Hungary, Italy, the Netherlands, Norway, Poland, Portugal, Russia, Slovenia, Spain, Sweden, Switzerland, the United Kingdom, and Ukraine) contributed to this essay, which evaluates one of the relatively few drugs to have been successfully introduced into the acute HF arena in recent times and charts a possible development trajectory for the next 20 years.
Papp Zoltán (1965-) (kardiológus, élettanász): Levosimendan Efficacy and Safety : 20 years of SIMDAX in Clinical Use
Tárgyszavak:
Orvostudományok
Elméleti orvostudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:
Journal Of Cardiovascular Pharmacology. - 76 : 1 (2020), p. 4-22. -
További szerzők:
Agostoni, Piergiuseppe
Alvarez, Julian
Bettex, Dominique
Bouchez, Stefan
Brito, Dulce
Cerny, Vladimir
Comin-Colet, Josep
Crespo-Leiro, Maria G.
Delgado, Juan F.
Édes István (1952-) (kardiológus)
Eremenko, Alexandr A.
Farmakis, Dimitrios
Fedele, Francesco
Fonseca, Candida
Fruhwald, Sonja
Girardis, Massimo
Guarracino, Fabio
Harjola, Veli-Pekka
Heringlake, Matthias
Herpain, Antoine
Heunks, Leo M. A.
Husebye, Trygve
Ivancan, Visnja
Karason, Kristian
Kaul, Sundeep
Kivikko, Matti
Kubica, Janek
Masip, Josep
Matskeplishvili, Simon
Mebazaa, Alexandre
Nieminen, Markku S.
Oliva, Fabrizio
Papp Gy. Julius (Szeged)
Parissis, John
Parkhomenko, Alexander
Põder, Pentti
Pölzl, Gerhard
Reinecke, Alexander
Ricksten, Sven-Erik
Riha, Hynek
Rudiger, Alain
Sarapohja, Toni
Schwinger, Robert H. G.
Toller, Wolfgang
Tritapepe, Luigi
Tschöpe, Carsten
Wikström, Gerhard
von Lewinski, Dirk
Vrtovec, Bojan
Pollesello, Piero
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Lásd még:
Egyéb kapcsolat
(1)
Borító:
Saját polcon:
2.
001-es BibID:
BIBFORM090869
035-os BibID:
(cikkazonosító)e19
Első szerző:
Papp Zoltán (kardiológus, élettanász)
Cím:
Levosimendan Efficacy and Safety : 20 years of SIMDAX in Clinical Use / Papp Zoltán, Agostoni Piergiuseppe, Alvarez Julian, Bettex Dominique, Bouchez Stefan, Brito Dulce, Černý Vladimir, Comin-Colet Josep, Crespo-Leiro Marisa G., Delgado Juan F., Édes Istvan, Eremenko Alexander A., Farmakis Dimitrios, Fedele Francesco, Fonseca Cândida, Fruhwald Sonja, Girardis Massimo, Guarracino Fabio, Harjola Veli-Pekka, Heringlake Matthias, Herpain Antoine, Heunks Leo M. A., Husebye Trygve, Ivancan Višnja, Karason Kristjan, Kaul Sundeep, Kivikko Matti, Kubica Janek, Masip Josep, Matskeplishvili Simon, Mebazaa Alexandre, Nieminen Markku S., Oliva Fabrizio, Papp Julius-Gyula, Parissis John, Parkhomenko Alexander, Põder Pentti, Pölzl Gerhard, Reinecke Alexander, Ricksten Sven-Erik, Riha Hynek, Rudiger Alain, Sarapohja Toni, Schwinger Robert H. G., Toller Wolfgang, Tritapepe Luigi, Tschöpe Carsten, Wikström Gerhard, von Lewinski Dirk, Vrtovec Bojan, Pollesello Piero
Dátum:
2020
Megjelenés:
Utánközlés / Másodközlés
ISSN:
2057-7540 2057-7559
Megjegyzések:
Levosimendan was first approved for clinic use in 2000, when authorisation was granted by Swedish regulatory authorities for the haemodynamic stabilisation of patients with acutely decompensated chronic heart failure. In the ensuing 20 years, this distinctive inodilator, which enhances cardiac contractility through calcium sensitisation and promotes vasodilatation through the opening of adenosine triphosphate-dependent potassium channels on vascular smooth muscle cells, has been approved in more than 60 jurisdictions, including most of the countries of the European Union and Latin America. Areas of clinical application have expanded considerably and now include cardiogenic shock, takotsubo cardiomyopathy, advanced heart failure, right ventricular failure and pulmonary hypertension, cardiac surgery, critical care and emergency medicine. Levosimendan is currently in active clinical evaluation in the US. Levosimendan in IV formulation is being used as a research tool in the exploration of a wide range of cardiac and non-cardiac disease states. A levosimendan oral form is at present under evaluation in the management of amyotrophic lateral sclerosis. To mark the 20 years since the advent of levosimendan in clinical use, 51 experts from 23 European countries (Austria, Belgium, Croatia, Cyprus, Czech Republic, Estonia, Finland, France, Germany, Greece, Hungary, Italy, the Netherlands, Norway, Poland, Portugal, Russia, Slovenia, Spain, Sweden, Switzerland, UK and Ukraine) contributed to this essay, which evaluates one of the relatively few drugs to have been successfully introduced into the acute heart failure arena in recent times and charts a possible development trajectory for the next 20 years.
Papp Zoltán (1965-) (kardiológus, élettanász): Levosimendan Efficacy and Safety : 20 Years of SIMDAX in Clinical Use
Tárgyszavak:
Orvostudományok
Elméleti orvostudományok
idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:
Cardiac Failure Review. - 6 (2020), p. 1-16. -
További szerzők:
Agostoni, Piergiuseppe
Alvarez, Julian
Bettex, Dominique
Bouchez, Stefan
Brito, Dulce
Cerny, Vladimir
Comin-Colet, Josep
Crespo-Leiro, Maria G.
Delgado, Juan F.
Édes István (1952-) (kardiológus)
Eremenko, Alexandr A.
Farmakis, Dimitrios
Fedele, Francesco
Fonseca, Candida
Fruhwald, Sonja
Girardis, Massimo
Guarracino, Fabio
Harjola, Veli-Pekka
Heringlake, Matthias
Herpain, Antoine
Heunks, Leo M. A.
Husebye, Trygve
Ivancan, Visnja
Karason, Kristian
Kaul, Sundeep
Kivikko, Matti
Kubica, Janek
Masip, Josep
Matskeplishvili, Simon
Mebazaa, Alexandre
Nieminen, Markku S.
Oliva, Fabrizio
Papp Gy. Julius (Szeged)
Parissis, John
Parkhomenko, Alexander
Põder, Pentti
Pölzl, Gerhard
Reinecke, Alexander
Ricksten, Sven-Erik
Riha, Hynek
Rudiger, Alain
Sarapohja, Toni
Schwinger, Robert H. G.
Toller, Wolfgang
Tritapepe, Luigi
Tschöpe, Carsten
Wikström, Gerhard
von Lewinski, Dirk
Vrtovec, Bojan
Pollesello, Piero
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Lásd még:
Utánközlés
(1)
Borító:
Saját polcon:
3.
001-es BibID:
BIBFORM003763
Első szerző:
Paulus, Walter J.
Cím:
How to diagnose diastolic heart failure : a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology / Paulus, W. J., Tschope, C., Sanderson, J. E., Rusconi, C., Flachskampf, F. A., Rademakers, F. E., Marino, P., Smiseth, O. A., De Keulenaer, G., Leite-Moreira, A. F., Borbely, A., Edes, I., Handoko, M. L., Heymans, S., Pezzali, N., Pieske, B., Dickstein, K., Fraser, A. G., Brutsaert, D. L.
Dátum:
2007
Megjegyzések:
Diastolic heart failure (DHF) currently accounts for more than 50% of all heart failure patients. DHF is also referred to as heart failure with normal left ventricular (LV) ejection fraction (HFNEF) to indicate that HFNEF could be a precursor of heart failure with reduced LVEF. Because of improved cardiac imaging and because of widespread clinical use of plasma levels of natriuretic peptides, diagnostic criteria for HFNEF needed to be updated. The diagnosis of HFNEF requires the following conditions to be satisfied: (i) signs or symptoms of heart failure; (ii) normal or mildly abnormal systolic LV function; (iii) evidence of diastolic LV dysfunction. Normal or mildly abnormal systolic LV function implies both an LVEF > 50% and an LV end-diastolic volume index (LVEDVI) <97 mL/m(2). Diagnostic evidence of diastolic LV dysfunction can be obtained invasively (LV end-diastolic pressure >16 mmHg or mean pulmonary capillary wedge pressure >12 mmHg) or non-invasively by tissue Doppler (TD) (E/E' > 15). If TD yields an E/E' ratio suggestive of diastolic LV dysfunction (15 > E/E' > 8), additional non-invasive investigations are required for diagnostic evidence of diastolic LV dysfunction. These can consist of blood flow Doppler of mitral valve or pulmonary veins, echo measures of LV mass index or left atrial volume index, electrocardiographic evidence of atrial fibrillation, or plasma levels of natriuretic peptides. If plasma levels of natriuretic peptides are elevated, diagnostic evidence of diastolic LV dysfunction also requires additional non-invasive investigations such as TD, blood flow Doppler of mitral valve or pulmonary veins, echo measures of LV mass index or left atrial volume index, or electrocardiographic evidence of atrial fibrillation. A similar strategy with focus on a high negative predictive value of successive investigations is proposed for the exclusion of HFNEF in patients with breathlessness and no signs of congestion. The updated strategies for the diagnosis and exclusion of HFNEF are useful not only for individual patient management but also for patient recruitment in future clinical trials exploring therapies for HFNEF
Tárgyszavak:
Orvostudományok
Klinikai orvostudományok
idegen nyelvű folyóiratközlemény külföldi lapban
Biological Markers
blood
Consensus
diagnosis
Diagnosis,Differential
Diastole
Echocardiography
Echocardiography,Doppler
Heart Failure
Humans
methods
Natriuretic Peptides
physiology
Stroke Volume
therapy
ultrasonography
Megjelenés:
European Heart Journal. - 28 : 20 (2007), p. 2539-2550. -
További szerzők:
Tschöpe, Carsten
Sanderson, John E.
Rusconi, Cesare
Flachskampf, Frank A.
Rademakers, Frank E.
Marino, Paolo
Smiseth, Otto A.
De Keulenaer, Gilles
Leite-Moreira, Adelino F.
Borbély Attila (1978-) (kardiológus)
Édes István (1952-) (kardiológus)
Handoko, Martin Louis
Heymans, Stephane
Pezzali, Natalia
Pieske, Burkert
Dickstein, Kenneth
Fraser, Alan G.
Brutsaert, Dirk L.
Internet cím:
elektronikus változat
DOI
Borító:
Saját polcon:
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