CCL

Összesen 5 találat.
#/oldal:
Részletezés:
Rendezés:

1.

001-es BibID:BIBFORM016576
035-os BibID:WOS:000278017700038
Első szerző:Amital, Howard
Cím:Serum concentrations of 25-OH vitamin D in patients with systemic lupus erythematosus (SLE) are inversely related to disease activity : is it time to routinely supplement patients with SLE with vitamin D? / Amital, H., Szekanecz, Z., Szucs, G., Danko, K., Nagy, E., Csepany, T., Kiss, E., Rovensky, J., Tuchynova, A., Kozakova, D., Doria, A., Corocher, N., Agmon-Levin, N., Barak, V., Orbach, H., Zandman-Goddard, G., Shoenfeld, Y.
Dátum:2010
ISSN:0003-4967
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
külföldön készült közlemény
Megjelenés:Annals Of The Rheumatic Diseases. - 69 : 6 (2010), p. 1155-1157. -
További szerzők:Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Szűcs Gabriella (1963-) (belgyógyász, allergológus és klinikai immunológus, reumatológus) Dankó Katalin (1952-2021) (belgyógyász, allergológus és klinikai immunológus) Nagy Endre V. (1957-) (belgyógyász, endokrinológus) Csépány Tünde (1956-) (neurológus, pszichiáter) Kiss E. (Budapest) Rovensky, Josef Tuchynova, Alena Kozakova, D. Doria, Andrea Corocher, Nadia Agmon-Levin, Nancy Barak, Vivian Orbach, Hedi Zandman-Goddard, Gisele Shoenfeld, Yehuda
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

2.

001-es BibID:BIBFORM015809
035-os BibID:PMID:21443034 WOS:000288183200006
Első szerző:Da Costa, Rafael
Cím:Ferritin and prolactin levels in multiple sclerosis / Rafael Da Costa, Martine Szyper-Kravitz, Zoltan Szekanecz, Tünde Csépány, Katalin Dankó, Yinon Shapira, Gisele Zandman-Goddard, Hedi Orbach, Nancy Agmon-Levin, Yehuda Shoenfeld
Dátum:2011
ISSN:1565-1088 (Print)
Megjegyzések:Multiple sclerosis (MS) is a common demyelnating disorder of the central nervous system (CNS) and ethiopathogenesis has yet to be fully elucidated. The disease may present in several clinical forms that are closely associated with disease morbidity. In recent years various environmental and hormonal factors have been implicated in the pathogenesis of autoimmunity. OBJECTIVES: To evaluate ferritin and prolactin levels in MS patients and their correlation with clinical manifestations of the disease. METHODS: Serum samples from 150 multiple sclerosis patients were evaluated for demographic characteristics, clinical parameters as well as prolactin and ferritin levels utilizing the Liaison chemiluminescent immunoassays (DiaSorin, Italy). Sera from 100 matched healthy donors were used as controls. RESULTS: Hyperprolactinemia was documented in 10 of 150 MS patients (6.7%) and hyperferritinemia in 12 (8%), both of which were significantly more common in this group compared with healthy controls (P < 0.01 and P = 0.02 respectively). Among female MS patients, elevated prolactin levels were related to the secondary-progressive type of disease (P = 0.05), whereas hyperferritinemia was associated with male gender (P = 0.03) and with the relapsing-progressive type of the disease (P = 0.02). An inverse association was found between hyperferritinemia and the relapsing-remitting type of MS in male patients (P = 0.05) CONCLUSIONS: Our results suggest a plausible association between these biomarkers and certain clinical types and gender among MS patients. Further studies combining clinical data, CNS imaging and these markers are warranted.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Adult
Biological Markers/blood
Female
Ferritins/*blood
Humans
Hyperprolactinemia/epidemiology
Incidence
Iron Metabolism Disorders/epidemiology
Male
Middle Aged
Multiple Sclerosis/*blood/epidemiology
Prolactin/*blood
külföldön készült közlemény
Megjelenés:The Israel Medical Association journal : IMAJ. - 13 : 2 (2011), p. 91-95. -
További szerzők:Szyper-Kravitz, Martine Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Csépány Tünde (1956-) (neurológus, pszichiáter) Dankó Katalin (1952-2021) (belgyógyász, allergológus és klinikai immunológus) Shapira, Yinon Zandman-Goddard, Gisele Orbach, Hedi Agmon-Levin, Nancy Shoenfeld, Yehuda
Internet cím:elektronikus változat
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

3.

001-es BibID:BIBFORM015838
Első szerző:Orbach, Hedi
Cím:Prolactin and Autoimmunity : hyperprolactinemia Correlates with Serositis and Anemia in SLE Patients / Orbach, H., Zandman-Goddard, G., Boaz, M., Agmon-Levin, N., Amital, H., Szekanecz, Z., Szucs, G., Rovensky, J., Kiss, E., Doria, A., Ghirardello, A., Gomez-Arbesu, J., Stojanovich, L., Ingegnoli, F., Meroni, P. L., Rozman, B., Blank, M., Shoenfeld, Y.
Dátum:2012
ISSN:1559-0267 (Electronic)
Megjegyzések:Evidence points to an association of prolactin to autoimmune diseases. We examined the correlation between hyperprolactinemia and disease manifestations and activity in a large patient cohort. Age- and sex-adjusted prolactin concentration was assessed in 256 serum samples from lupus patients utilizing the LIASON prolactin automated immunoassay method (DiaSorin S.p.A, Saluggia, Italy). Disease activity was defined as present if European Consensus Lupus Activity Measurement (ECLAM) > 2 or Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) > 4. Lupus manifestations were grouped by organ involvement, laboratory data, and prescribed medications. Hyperprolactinemia was presented in 46/256 (18%) of the cohort. Hyperprolactinemic patients had significantly more serositis (40% vs. 32.4%, p = 0.03) specifically, pleuritis (33% vs. 17%, p = 0.02), pericarditis (30% vs. 12%, p = 0.002), and peritonitis (15% vs. 0.8%, p = 0.003). Hyperprolactinemic subjects exhibited significantly more anemia (42% vs. 26%, p = 0.02) and marginally more proteinuria (65.5% vs. 46%, p = 0.06). Elevated levels of prolactin were not significantly associated with other clinical manifestations, serology, or therapy. Disease activity scores were not associated with hyperprolactinemia. Hyperprolactinemia in lupus patients is associated with all types of serositis and anemia but not with other clinical, serological therapeutic measures or with disease activity. These results suggest that dopamine agonists may be an optional therapy for lupus patients with hyperprolactinemia.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Clinical Reviews in Allergy and Immunology. - 42 : 2 (2012), p. 189-198. -
További szerzők:Zandman-Goddard, Gisele Boaz, Mona Agmon-Levin, Nancy Amital, Howard Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Szűcs Gabriella (1963-) (belgyógyász, allergológus és klinikai immunológus, reumatológus) Rovensky, Josef Kiss Emese (1960-) (belgyógyász, immunológus) Doria, Andrea Ghirardello, A. Gomez-Arbesu, Jesus Stojanovich, Ljudmila Ingegnoli, Francesca Meroni, Pier Luigi Rozman, Blaz Blank, Marion Shoenfeld, Yehuda
Internet cím:DOI
elektronikus változat
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

4.

001-es BibID:BIBFORM002305
035-os BibID:PMID:17785327 WOS:000249589100045
Első szerző:Orbach, Hedi
Cím:Novel biomarkers in autoimmune diseases prolactin, ferritin, vitamin D, and TPA levels in autoimmune diseases / Hedi Orbach, Gisele Zandman-Goddard, Howard Amital, Vivian Barak, Zoltan Szekanecz, Gabriella Szűcs, Katalin Dankó, Endre V. Nagy, Tünde Csépány, Jozelio F. Carvalho, Andrea Doria, Yehuda Shoenfeld
Dátum:2007
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
külföldön készült közlemény
Megjelenés:Annals of the New York Academy of Sciences 1109 (2007), p. 385-400. -
További szerzők:Zandman-Goddard, Gisele Amital, Howard Barak, Vivian Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Szűcs Gabriella (1963-) (belgyógyász, allergológus és klinikai immunológus, reumatológus) Dankó Katalin (1952-2021) (belgyógyász, allergológus és klinikai immunológus) Nagy Endre V. (1957-) (belgyógyász, endokrinológus) Csépány Tünde (1956-) (neurológus, pszichiáter) Carvalho, Jozelio F. Doria, Andrea Shoenfeld, Yehuda
Internet cím:elektronikus változat
DOI
Borító:

5.

001-es BibID:BIBFORM015927
Első szerző:Zandman-Goddard, Gisele
Cím:Hyperferritinemia is Associated with Serologic Antiphospholipid Syndrome in SLE Patients / Zandman-Goddard, G., Orbach, H., Agmon-Levin, N., Boaz, M., Amital, H., Szekanecz, Z., Szucs, G., Rovensky, J., Kiss, E., Corocher, N., Doria, A., Stojanovich, L., Ingegnoli, F., Meroni, P. L., Rozman, B., Gomez-Arbesu, J., Blank, M., Shoenfeld, Y.
Dátum:2013
ISSN:1559-0267 (Electronic)
Megjegyzések:Ferritin may play a direct role on the immune system. We sought to determine if elevated levels of ferritin in lupus patients correlate with disease activity and organ involvement in a large cohort. Ferritin levels (gender and age adjusted) were assessed in 274 lupus serum samples utilizing the LIASON Ferritin automated immunoassay method. Significant disease activity was determined if European Consensus Lupus Activity Index (ECLAM) > 2 or Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) > 4. Utilizing an EXCEL database, we compared elevated ferritin levels to manifestations grouped by organ involvement, serology, and previous therapy. The patients were predominantly female (89%), median age was 37 years old, and disease duration was 10.6 +/- 7.7 years. Hyperferritinemia was found in 18.6% of SLE patients. Compared to subjects with normal ferritin levels, a significantly greater proportion of patients with hyperferritinemia had thrombocytopenia (15.4% vs. 33.3%, p = 0.003) and lupus anticoagulant (11.3% vs. 29.0%, p = 0.01). Additionally, compared to normoferritinemic subjects, hyperferritinemic subjects had significantly higher total aCL (99.7 +/- 369 vs. 30.9 +/- 17.3 GPI, p = 0.02) and aCL IgM antibody levels (75.3 +/- 357.4 vs. 9.3 +/- 10.3 GPI, p = 0.02), and marginally lower aCL IgG antibody levels (9.2 +/- 4.9 vs. 9.7 +/- 3.9 GPI, p = 0.096). While the ECLAM score significantly correlated with hyperferritinemia (p = 0.04), the SLEDAI score was marginally associated with hyperferritinemia (p = 0.1). Serositis was marginally associated with hyperferritinemia, but not with other manifestations. An association with serologic APS was encountered. Hyperferritinemia was associated with thrombocytopenia, lupus anticoagulant, and anti-cardiolipin antibodies suggest that it may be an early marker for secondary antiphospholipid syndrome in SLE patients.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Clinical Reviews in Allergy and Immunology. - 44 : 1 (2013), p. 23-30. -
További szerzők:Orbach, Hedi Agmon-Levin, Nancy Boaz, Mona Amital, Howard Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Szűcs Gabriella (1963-) (belgyógyász, allergológus és klinikai immunológus, reumatológus) Rovensky, Josef Kiss Emese (1960-) (belgyógyász, immunológus) Corocher, Nadia Doria, Andrea Stojanovich, Ljudmila Ingegnoli, Francesca Meroni, Pier Luigi Rozman, Blaz Gomez-Arbesu, Jesus Blank, Miri Shoenfeld, Yehuda
Internet cím:DOI
elektronikus változat
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Rekordok letöltése1 
Corvina könyvtári katalógus v8.2.27 © 2023 Monguz kft. Minden jog fenntartva.