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001-es BibID:	BIBFORM007053
Első szerző:	Bodolay Edit (belgyógyász, allergológus és klinikai immunológus)
Cím:	Angiogenesis and chemokines in rheumatoid arthritis and other systemic inflammatory rheumatic diseases / Bodolay, E., Koch, A. E., Kim, J., Szegedi, G., Szekanecz, Z.
Dátum:	2002
ISSN:	1582-1838 (Print)
Megjegyzések:	Angiogenesis, the formation of new vessels, is important in the pathogenesis of rheumatoid arthritis (RA) and other inflammatory diseases. Chemotactic cytokines termed chemokines mediate the ingress of leukocytes, including neutrophils and monocytes into the inflamed synovium. In this review, authors discuss the role of the most important angiogenic factors and angiogenesis inhibitors, as well as relevant chemokines and chemokine receptors involved in chronic inflammatory rheumatic diseases. RA was chosen as a prototype to discuss these issues, as the majority of studies on the role of angiogenesis and chemokines in inflammatory diseases were carried out in arthritis. However, other systemic inflammatory (autoimmune) diseases including systemic lupus erythematosus (SLE), systemic sclerosis (SSc), Sjogren's syndrome (SS), mixed connective tissue disease (MCTD), polymyositis/dermatomyositis (PM/DM) and systemic vasculites are also discussed in this context. As a number of chemokines may also play a role in neovascularization, this issue is also described here. Apart from discussing the pathogenic role of angiogenesis and chemokines, authors also review the regulation of angiogenesis and chemokine production by other inflammatory mediators, as well as the important relevance of neovascularization and chemokines for antirheumatic intervention.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Angiogenesis Inhibitors Arthritis, Rheumatoid Autoimmune Diseases Chemokines Growth Substances Humans Neovascularization, Pathologic Receptors, Chemokine
Megjelenés:	Journal of Cellular and Molecular Medicine. - 6 : 3 (2002), p. 357-376. -
További szerzők:	Koch, Alisa E. Kim, Joon Szegedi Gyula (1936-2013) (belgyógyász, immunológus) Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus)
Internet cím:	elektronikus változat Intézményi repozitóriumban (DEA) tárolt változat DOI
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001-es BibID:	BIBFORM094102
Első szerző:	Szekanecz Zoltán (reumatológus, belgyógyász, immunológus)
Cím:	Angiogenesis in rheumatoid anhritis / Zoltán Szekanecz, Joon Kim, Alisa E. Koch
Dátum:	2002
Megjegyzések:	Angiogenesis, the formation of new blood vessels, enables the emigration of leukocytes into tissues. Neovascularization is a crucial process in the pathogenesis of inflammatory and malignant disorders. Rheumatoid arthritis (RA) is considered by many as an "angiogenic disease". A number of angiogenic mediators including cytokines, chemokines, growth factors, matrix components, adhesion molecules, proteolytic enzymes and others are abundantly produced in the RA synovium. These factors stimulate the proliferation and migration of endothelial cells followed by capillary formation.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Recent Res. Devel. lmmunology. - 4 (2002), p. 523-533. -
További szerzők:	Kim, Joon Koch, Alisa E.
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM007110
Első szerző:	Szekanecz Zoltán (reumatológus, belgyógyász, immunológus)
Cím:	Chemokines and chemokine receptors in rheumatoid arthritis / Szekanecz, Z., Kim, J., Koch, A. E.
Dátum:	2003
ISSN:	1044-5323 (Print)
Megjegyzések:	Chemokines are chemotactic cytokines involved in a number of pathological processes, including inflammatory conditions. Chemokines play a role in the pathogenesis of various inflammatory diseases. Based on a burgeoning body of literature, RA was chosen as a prototype to discuss this issue. In this review, the authors give a detailed introduction to the classification and function of chemokines and their receptors. This is followed by a discussion of the role of chemokines and chemokine receptors in RA. Chemokines interact with other inflammatory mediators, such as cytokines. Thus, the regulation of chemokine production and the place of chemokines in the network of inflammatory mediators present in the rheumatoid synovium are also reviewed. Finally, potential strategies using anti-chemokine or anti-chemokine receptor biologicals in anti-rheumatic therapy are discussed.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Animals Arthritis, Rheumatoid Chemokines Cytokines Humans Receptors, Chemokine T-Lymphocytes
Megjelenés:	Seminars in Immunology. - 15 : 1 (2003), p. 15-21. -
További szerzők:	Kim, Joon Koch, Alisa E.
Internet cím:	elektronikus változat elektronikus változat
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