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001-es BibID:BIBFORM067427
035-os BibID:(WoS)000401138800008 (Scopus)85007256365
Első szerző:Combe, Bernard
Cím:2016 update of the EULAR recommendations for the management of early arthritis / Bernard Combe, Robert Landewe, Claire I. Daien, Charlotte Hua, Daniel Aletaha, Jose María Álvaro-Gracia, Margôt Bakkers, Nina Brodin, Gerd R. Burmester, Catalin Codreanu, Richard Conway, Maxime Dougados, Paul Emery, Gianfranco Ferraccioli, Joao Fonseca, Karim Raza, Lucía Silva-Fernández, Josef S. Smolen, Diana Skingle, Zoltan Szekanecz, Tore K. Kvien, Annette van der Helm-van Mil, Ronald van Vollenhoven
Dátum:2017
ISSN:0003-4967
Megjegyzések:Objectives Since the 2007 recommendations for the management of early arthritis have been presented, considerable research has been published in the field of early arthritis, mandating an update of the 2007 European League Against Rheumatism (EULAR) recommendations for management of early arthritis.Methods In accordance with the 2014 EULAR Standardised Operating Procedures, the expert committee pursued an approach that was based on evidence in the literature and on expert opinion. The committee involved 20 rheumatologists, 2 patients and 1 healthcare professional representing 12 European countries. The group defined the focus of the expert committee and target population, formulated a definition of ♭management' and selected the research questions. A systematic literature research (SLR) was performed by two fellows with the help of a skilled librarian. A set of draft recommendations was proposed on the basis of the research questions and the results of the SLR. For each recommendation, the categories of evidence were identified, the strength of recommendations was derived and the level of agreement was determined through a voting process.Results The updated recommendations comprise 3 overarching principles and 12 recommendations for managing early arthritis. The selected statements involve the recognition of arthritis, referral, diagnosis, prognostication, treatment (information, education, pharmacological and non-pharmacological interventions), monitoring and strategy. Eighteen items were identified as relevant for future research.Conclusions These recommendations provide rheumatologists, general practitioners, healthcare professionals, patients and other stakeholders with an updated EULAR consensus on the entire management of early arthritis.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Annals Of The Rheumatic Diseases. - 76 : 6 (2017), p. 948-959. -
További szerzők:Landewé, Robert Daien, Claire I. Hua, Charlotte Aletaha, Daniel Álvaro-Gracia, Jose María Bakkers, Margôt Brodin, Nina Burmester, Gerd R. Codreanu, Catalin Conway, Richard Dougados, Maxime Emery, Paul Ferraccioli, Gianfranco Fonseca, João Raza, Karim Silva-Fernández, Lucía Smolen, Josef S. Skingle, Diana Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Kvien, Tore K. van der Helm-van Mil, Annette van Vollenhoven, Ronald
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2.

001-es BibID:BIBFORM075623
035-os BibID:(cikkazonosító)e000780 (WoS)000455537200030 (Scopus)85058345877
Első szerző:Dejaco, Christian
Cím:EULAR 'points to consider' for the conduction of workforce requirement studies in rheumatology / Christian Dejaco, Polina Putrik, Julia Unger, Daniel Aletaha, Gerolamo Bianchi, Johannes W. Bijlsma, Annelies Boonen, Nada Cikes, Axel Finck, Laure Gossec, Tore K. Kvien, Joao Madruga Dias, Eric L. Matteson, Francisca Sivera, Tanja A. Stamm, Zoltan Szekanecz, Dieter Wiek, Angela Zink, Sofia Ramiro, Frank Buttgereit
Dátum:2018
ISSN:2056-5933
Megjegyzések:Objective: Current methods used for forecasting workforce requirements in rheumatology are disparate, as are the parameters incorporated into workforce projection studies. The objective of these European League Against Rheumatism (EULAR points to consider (PTC) is to guide future workforce studies in adult rheumatology in order to produce valid and reliable manpower estimates. Methods: The EULAR Standardised Operating Procedures were followed. A multidisciplinary task force with experts including patients with rheumatic diseases from 11 EULAR countries and the USA was assembled. A systematic literature review (SLR) was conducted to retrieve workforce models in rheumatology and other medical fields. PTC were based on expert opinion informed by the SLR, followed by group discussions with consensus obtained through informal voting. The level of agreement with the PTC was voted anonymously. Results: A total of 10 PTC were formulated. The task force recommends models integrating supply (=workforce available in rheumatology), demand (=health services requested by the population) and need (=health services that are considered appropriate to serve the population). In general, projections of workforce requirements should consider all factors relevant for current and future workload in rheumatology inside and outside of direct patient care. Forecasts of workforce supply should consider demography and attrition of rheumatologists, as well as the effects of new developments in healthcare. Predictions of future need/demand should take demographic, sociocultural and epidemiological development of the population into account. Conclusion: These EULAR-endorsed PTC will provide guidance on the methodology and the parameters to be applied in future national and international workforce requirement studies in rheumatology.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:RMD Open. - 4 : 2 (2018), p. 1-8. -
További szerzők:Putrik, Polina Unger, Julia Aletaha, Daniel Bianchi, Gerolamo Bijlsma, Johannes W. Boonen, Annelies Cikes, Nada Finck, Axel Gossec, Laure Kvien, Tore K. Dias, João Madruga Matteson, Eric L. Sivera, Francisca Stamm, Tanja A. Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Wiek, Dieter Zink, Angela Ramiro, Sofia Buttgereit, Frank
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3.

001-es BibID:BIBFORM101635
035-os BibID:(WOS)000788197600001 (Scopus)85130637905
Első szerző:McInnes, Iain B.
Cím:Reflections on a contemporary European tragedy / Iain B. McInnes, Annamaria Iagnocco, Daniel Aletaha, Xenofon Baraliakos, Johannes W. J. Bijlsma, Elsa F. Mateus, Zoltan Szekanecz, Theodora P. M. Vliet Vlieland, Josef S. Smolen
Dátum:2022
ISSN:0003-4967
Tárgyszavak:Orvostudományok Klinikai orvostudományok szerkesztőségi anyag
folyóiratcikk
Megjelenés:Annals Of The Rheumatic Diseases. - 81 :6 (2022), p. 747-748. -
További szerzők:Iagnocco, Annamaria Aletaha, Daniel Baraliakos, Xenofon Bijlsma, Johannes W. Mateus, Elsa F. Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Vlieland, Theodora P. M. Vliet Smolen, Josef S.
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4.

001-es BibID:BIBFORM096109
035-os BibID:(WOS)000723328800001 (Scopus)85122302204
Első szerző:Nagy György
Cím:EULAR points to consider for the management of difficult-to-treat rheumatoid arthritis / Nagy György, Roodenrijs Nadia M. T., Welsing Paco M. J., Kedves Melinda, Hamar Attila, van der Goes Marlies C., Kent Alison, Bakkers Margot, Pchelnikova Polina, Blaas Etienne, Senolt Ladislav, Szekanecz Zoltan, Choy Ernest H., Dougados Maxime, Jacobs Johannes W. G., Geenen Rinie, Bijlsma Johannes W. J., Zink Angela, Aletaha Daniel, Schoneveld Leonard, van Riel Piet, Dumas Sophie, Prior Yeliz, Nikiphorou Elena, Ferraccioli Gianfranco, Schett Georg, Hyrich Kimme L., Mueller-Ladner Ulf, Buch Maya H., McInnes Iain B., van der Heijde Désirée, van Laar Jacob M.
Dátum:2022
ISSN:0003-4967
Megjegyzések:Objective To develop evidence-based European Alliance of Associations for Rheumatology (EULAR) points to consider (PtCs) for the management of difficultto-treat rheumatoid arthritis (D2T RA). Methods An EULAR Task Force was established comprising 34 individuals: 26 rheumatologists, patient partners and rheumatology experienced health professionals. Two systematic literature reviews addressed clinical questions around diagnostic challenges, and pharmacological and nonpharmacological therapeutic strategies in D2T RA. PtCs were formulated based on the identified evidence and expert opinion. Strength of recommendations (SoR, scale A?D: A typically consistent level 1 studies and D level 5 evidence or inconsistent studies) and level of agreement (LoA, scale 0?10: 0 completely disagree and 10 completely agree) of the PtCs were determined by the Task Force members. Results Two overarching principles and 11 PtCs were defined concerning diagnostic confirmation of RA, evaluation of inflammatory disease activity, pharmacological and non-pharmacological interventions, treatment adherence, functional disability, pain, fatigue, goal setting and self-efficacy and the impact of comorbidities. The SoR varied from level C to level D. The mean LoA with the overarching principles and PtCs was generally high (8.4?9.6). Conclusions These PtCs for D2T RA can serve as a clinical roadmap to support healthcare professionals and patients to deliver holistic management and more personalised pharmacological and non-pharmacological therapeutic strategies. High-quality evidence was scarce. A research agenda was created to guide future research.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
arthritis
fibromyalgia
inflammation
rheumatoid
ultrasonography
Megjelenés:Annals Of The Rheumatic Diseases. - 81 : 1 (2022), p. 20-33. -
További szerzők:Roodenrijs, Nadia M. T. Welsing, Paco M. J. Kedves Melinda Hamar Attila Béla (1990-) (általános orvos) van der Goes, Marlies C. Kent, Alison Bakkers, Margôt Pchelnikova, Polina Blaas, Etienne Senolt, Ladislav Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Choy, Ernest Dougados, Maxime Jacobs, Johannes W. G. Geenen, Rinie Bijlsma, Johannes W. Zink, Angela Aletaha, Daniel Schoneveld, Leonard van Riel, Piet Dumas, Sophie Prior, Yeliz Nikiphorou, Elena (reumatológus) Ferraccioli, Gianfranco Schett, Georg Hyrich, Kimme L. Mueller-Ladner, Ulf Buch, Maya H. McInnes, Iain B. van der Heijde, Désirée van Laar, Jacob M.
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5.

001-es BibID:BIBFORM088182
035-os BibID:(WOS)000607296800019 (Scopus)85098069546
Első szerző:Nagy György
Cím:EULAR definition of difficult-to-treat rheumatoid arthritis / György Nagy, Nadia M. T. Roodenrijs, Paco M. J. Welsing, Melinda Kedves, Attila Hamar, Marlies C. van der Goes, Alison Kent, Margot Bakkers, Etienne Blaas, Ladislav Senolt, Zoltan Szekanecz, Ernest Choy, Maxime Dougados, Johannes W. G. Jacobs, Rinie Geenen, Hans W. J. Bijlsma, Angela Zink, Daniel Aletaha, Leonard Schoneveld, Piet van Riel, Loriane Gutermann, Yeliz Prior, Elena Nikiphorou, Gianfranco Ferraccioli, Georg Schett, Kimme L. Hyrich, Ulf Mueller-Ladner, Maya H. Buch, Iain B. McInnes, Désirée van der Heijde, Jacob M. van Laar
Dátum:2021
ISSN:0003-4967
Megjegyzések:Background Despite treatment according to the current management recommendations, a significant proportion of patients with rheumatoid arthritis (RA) remain symptomatic. These patients can be considered to have 'difficult-to-treat RA'. However, uniform terminology and an appropriate definition are lacking. Objective The Task Force in charge of the "Development of EULAR recommendations for the comprehensive management of difficult-to-treat rheumatoid arthritis" aims to create recommendations for this underserved patient group. Herein, we present the definition of difficult-to-treat RA, as the first step. Methods The Steering Committee drafted a definition with suggested terminology based on an international survey among rheumatologists. This was discussed and amended by the Task Force, including rheumatologists, nurses, health professionals and patients, at a face-to-face meeting until sufficient agreement was reached (assessed through voting). Results The following three criteria were agreed by all Task Force members as mandatory elements of the definition of difficult-to-treat RA: (1) Treatment according to European League Against Rheumatism (EULAR) recommendation and failure of ?2 biological disease-modifying antirheumatic drugs (DMARDs)/targeted synthetic DMARDs (with different mechanisms of action) after failing conventional synthetic DMARD therapy (unless contraindicated); (2) presence of at least one of the following: at least moderate disease activity; signs and/or symptoms suggestive of active disease; inability to taper glucocorticoid treatment; rapid radiographic progression; RA symptoms that are causing a reduction in quality of life; and (3) the management of signs and/or symptoms is perceived as problematic by the rheumatologist and/or the patient. Conclusions The proposed EULAR definition for difficult-to-treat RA can be used in clinical practice, clinical trials and can form a basis for future research.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Annals Of The Rheumatic Diseases. - 80 : 1 (2021), p. 31-35. -
További szerzők:Roodenrijs, Nadia M. T. Welsing, Paco M. J. Kedves Melinda Hamar Attila Béla (1990-) (általános orvos) Goes, Marlies C. van der Kent, Alison Bakkers, Margôt Blaas, Etienne Senolt, Ladislav Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Choy, Ernest Dougados, Maxime Jacobs, Johannes W. G. Geenen, Rinie Bijlsma, Johannes W. Zink, Angela Aletaha, Daniel Schoneveld, Leonard Riel, Piet van Gutermann, Loriane Prior, Yeliz Nikiphorou, Elena (reumatológus) Ferraccioli, Gianfranco Schett, Georg Hyrich, Kimme L. Mueller-Ladner, Ulf Buch, Maya H. McInnes, Iain B. Heijde, Désirée van der Laar, Jacob M. van
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6.

001-es BibID:BIBFORM075277
035-os BibID:(WoS)000451780400011 (Scopus)85053158051
Első szerző:Roodenrijs, Nadia M. T.
Cím:Characteristics of difficult-to-treat rheumatoid arthritis : results of an international survey / Nadia M. T. Roodenrijs, Maria J. H. de Hair, Marlies C. van der Goes, Johannes W. G. Jacobs, Paco M. J. Welsing, Désirée van der Heijde, Daniel Aletaha, Maxime Dougados, Kimme L. Hyrich, Iain B. McInnes, Ulf Mueller-Ladner, Ladislav Senolt, Zoltan Szekanecz, Jacob M. van Laar, György Nagy, EULAR Task Force on development of EULAR recommendations for the comprehensive management of difficult-to-treat rheumatoid arthritis
Dátum:2018
ISSN:0003-4967
Megjegyzések:Patients with difficult-to-treat rheumatoid arthritis (RA) remain symptomatic despite treatment according to current European League Against Rheumatism (EULAR) management recommendations. These focus on early phases of the disease and pharmacological management. We aimed to identify characteristics of difficult-to-treat RA and issues to be addressed in its workup and management that are not covered by current management recommendations. METHODS: An international survey was conducted among rheumatologists with multiple-choice questions on disease characteristics of difficult-to-treat RA. Using open questions, additional items to be addressed and items missing in current management recommendations were identified. RESULTS: 410 respondents completed the survey: 50% selected disease activity score assessing 28 joints >3.2 OR presence of signs suggestive of active disease as characteristics of difficult-to-treat RA; 42% selected fatigue; 48% selected failure to ?2 conventional synthetic disease-modifying antirheumatic drugs (DMARDs) AND ?2 biological/targeted synthetic DMARDs; 89% selected inability to taper glucocorticoids below 5 mg or 10 mg prednisone equivalent daily. Interfering comorbidities, extra-articular manifestations and polypharmacy were identified as important issues missing in current management recommendations. CONCLUSIONS: There is wide variation in concepts of difficult-to-treat RA. Several important issues regarding these patients are not addressed by current EULAR recommendations.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
disease activity
rheumatoid Arthritis
treatment
Megjelenés:Annals Of The Rheumatic Diseases. - 77 (2018), p. 1705-1709. -
További szerzők:Hair, Maria J. H. de Goes, Marlies C. van der Jacobs, Johannes W. G. Welsing, Paco M. J. Heijde, Désirée van der Aletaha, Daniel Dougados, Maxime Hyrich, Kimme L. McInnes, Iain B. Mueller-Ladner, Ulf Senolt, Ladislav Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Laar, Jacob M. van Nagy György EULAR Task Force on development of EULAR recommendations for the comprehensive management of difficult-to-treat rheumatoid arthritis
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7.

001-es BibID:BIBFORM076711
035-os BibID:(cikkazonosító)e000756
Első szerző:Unger, Julia
Cím:Workforce requirements in rheumatology : a systematic literature review informing the development of a workforce prediction risk of bias tool and the EULAR points to consider / Julia Unger, Polina Putrik, Frank Buttgereit, Daniel Aletaha, Gerolamo Bianchi, Johannes W. J. Bijlsma, Annelies Boonen, Nada Cikes, João Madruga Dias, Louise Falzon, Axel Finckh, Laure Gossec, Tore K. Kvien, Eric L. Matteson, Francisca Sivera, Tanja A. Stamm, Zoltan Szekanecz, Dieter Wiek, Angela Zink, Christian Dejaco, Sofia Ramiro
Dátum:2018
Megjegyzések:Objective?To summarise the available information on physician workforce modelling, to develop a rheumatology workforce prediction risk of bias tool and to apply it to existing studies in rheumatology. Methods?A systematic literature review (SLR) was performed in key electronic databases (1946?2017) comprising an update of an SLR in rheumatology and a hierarchical SLR in other medical fields. Data on the type of workforce prediction models and the factors considered in the models were extracted. Key general as well as specific need/demand and supply factors for workforce calculation in rheumatology were identified. The workforce prediction risk of bias tool was developed and applied to existing workforce studies in rheumatology. Results?In total, 14 studies in rheumatology and 10 studies in other medical fields were included. Studies used a variety of prediction models based on a heterogeneous set of need/demand and/or supply factors. Only two studies attempted empirical validation of the prediction quality of the model. Based on evidence and consensus, the newly developed risk of bias tool includes 21 factors (general, need/demand and supply). The majority of studies revealed high or moderate risk of bias for most of the factors. Conclusions?The existing evidence on workforce prediction in rheumatology is scarce, heterogeneous and at moderate or high risk of bias. The new risk of bias tool should enable future evaluation of workforce prediction studies. This review informs the European League Against Rheumatism points to consider for the conduction of workforce requirement studies in rheumatology.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Rheumatic and Musculoskeletal Diseases. - 4 : 2 (2018), p. 1-19. -
További szerzők:Putrik, Polina Buttgereit, Frank Aletaha, Daniel Bianchi, Gerolamo Bijlsma, Johannes W. Boonen, Annelies Cikes, Nada Dias, João Madruga Falzon, Louise Finckh, Axel Gossec, Laure Kvien, Tore K. Matteson, Eric L. Sivera, Francisca Stamm, Tanja A. Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Wiek, Dieter Zink, Angela Dejaco, Christian Ramiro, Sofia
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