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001-es BibID:BIBFORM096109
035-os BibID:(WOS)000723328800001 (Scopus)85122302204
Első szerző:Nagy György
Cím:EULAR points to consider for the management of difficult-to-treat rheumatoid arthritis / Nagy György, Roodenrijs Nadia M. T., Welsing Paco M. J., Kedves Melinda, Hamar Attila, van der Goes Marlies C., Kent Alison, Bakkers Margot, Pchelnikova Polina, Blaas Etienne, Senolt Ladislav, Szekanecz Zoltan, Choy Ernest H., Dougados Maxime, Jacobs Johannes W. G., Geenen Rinie, Bijlsma Johannes W. J., Zink Angela, Aletaha Daniel, Schoneveld Leonard, van Riel Piet, Dumas Sophie, Prior Yeliz, Nikiphorou Elena, Ferraccioli Gianfranco, Schett Georg, Hyrich Kimme L., Mueller-Ladner Ulf, Buch Maya H., McInnes Iain B., van der Heijde Désirée, van Laar Jacob M.
Dátum:2022
ISSN:0003-4967
Megjegyzések:Objective To develop evidence-based European Alliance of Associations for Rheumatology (EULAR) points to consider (PtCs) for the management of difficultto-treat rheumatoid arthritis (D2T RA). Methods An EULAR Task Force was established comprising 34 individuals: 26 rheumatologists, patient partners and rheumatology experienced health professionals. Two systematic literature reviews addressed clinical questions around diagnostic challenges, and pharmacological and nonpharmacological therapeutic strategies in D2T RA. PtCs were formulated based on the identified evidence and expert opinion. Strength of recommendations (SoR, scale A?D: A typically consistent level 1 studies and D level 5 evidence or inconsistent studies) and level of agreement (LoA, scale 0?10: 0 completely disagree and 10 completely agree) of the PtCs were determined by the Task Force members. Results Two overarching principles and 11 PtCs were defined concerning diagnostic confirmation of RA, evaluation of inflammatory disease activity, pharmacological and non-pharmacological interventions, treatment adherence, functional disability, pain, fatigue, goal setting and self-efficacy and the impact of comorbidities. The SoR varied from level C to level D. The mean LoA with the overarching principles and PtCs was generally high (8.4?9.6). Conclusions These PtCs for D2T RA can serve as a clinical roadmap to support healthcare professionals and patients to deliver holistic management and more personalised pharmacological and non-pharmacological therapeutic strategies. High-quality evidence was scarce. A research agenda was created to guide future research.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
arthritis
fibromyalgia
inflammation
rheumatoid
ultrasonography
Megjelenés:Annals Of The Rheumatic Diseases. - 81 : 1 (2022), p. 20-33. -
További szerzők:Roodenrijs, Nadia M. T. Welsing, Paco M. J. Kedves Melinda Hamar Attila Béla (1990-) (általános orvos) van der Goes, Marlies C. Kent, Alison Bakkers, Margôt Pchelnikova, Polina Blaas, Etienne Senolt, Ladislav Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Choy, Ernest Dougados, Maxime Jacobs, Johannes W. G. Geenen, Rinie Bijlsma, Johannes W. Zink, Angela Aletaha, Daniel Schoneveld, Leonard van Riel, Piet Dumas, Sophie Prior, Yeliz Nikiphorou, Elena (reumatológus) Ferraccioli, Gianfranco Schett, Georg Hyrich, Kimme L. Mueller-Ladner, Ulf Buch, Maya H. McInnes, Iain B. van der Heijde, Désirée van Laar, Jacob M.
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2.

001-es BibID:BIBFORM088182
035-os BibID:(WOS)000607296800019 (Scopus)85098069546
Első szerző:Nagy György
Cím:EULAR definition of difficult-to-treat rheumatoid arthritis / György Nagy, Nadia M. T. Roodenrijs, Paco M. J. Welsing, Melinda Kedves, Attila Hamar, Marlies C. van der Goes, Alison Kent, Margot Bakkers, Etienne Blaas, Ladislav Senolt, Zoltan Szekanecz, Ernest Choy, Maxime Dougados, Johannes W. G. Jacobs, Rinie Geenen, Hans W. J. Bijlsma, Angela Zink, Daniel Aletaha, Leonard Schoneveld, Piet van Riel, Loriane Gutermann, Yeliz Prior, Elena Nikiphorou, Gianfranco Ferraccioli, Georg Schett, Kimme L. Hyrich, Ulf Mueller-Ladner, Maya H. Buch, Iain B. McInnes, Désirée van der Heijde, Jacob M. van Laar
Dátum:2021
ISSN:0003-4967
Megjegyzések:Background Despite treatment according to the current management recommendations, a significant proportion of patients with rheumatoid arthritis (RA) remain symptomatic. These patients can be considered to have 'difficult-to-treat RA'. However, uniform terminology and an appropriate definition are lacking. Objective The Task Force in charge of the "Development of EULAR recommendations for the comprehensive management of difficult-to-treat rheumatoid arthritis" aims to create recommendations for this underserved patient group. Herein, we present the definition of difficult-to-treat RA, as the first step. Methods The Steering Committee drafted a definition with suggested terminology based on an international survey among rheumatologists. This was discussed and amended by the Task Force, including rheumatologists, nurses, health professionals and patients, at a face-to-face meeting until sufficient agreement was reached (assessed through voting). Results The following three criteria were agreed by all Task Force members as mandatory elements of the definition of difficult-to-treat RA: (1) Treatment according to European League Against Rheumatism (EULAR) recommendation and failure of ?2 biological disease-modifying antirheumatic drugs (DMARDs)/targeted synthetic DMARDs (with different mechanisms of action) after failing conventional synthetic DMARD therapy (unless contraindicated); (2) presence of at least one of the following: at least moderate disease activity; signs and/or symptoms suggestive of active disease; inability to taper glucocorticoid treatment; rapid radiographic progression; RA symptoms that are causing a reduction in quality of life; and (3) the management of signs and/or symptoms is perceived as problematic by the rheumatologist and/or the patient. Conclusions The proposed EULAR definition for difficult-to-treat RA can be used in clinical practice, clinical trials and can form a basis for future research.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Annals Of The Rheumatic Diseases. - 80 : 1 (2021), p. 31-35. -
További szerzők:Roodenrijs, Nadia M. T. Welsing, Paco M. J. Kedves Melinda Hamar Attila Béla (1990-) (általános orvos) Goes, Marlies C. van der Kent, Alison Bakkers, Margôt Blaas, Etienne Senolt, Ladislav Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Choy, Ernest Dougados, Maxime Jacobs, Johannes W. G. Geenen, Rinie Bijlsma, Johannes W. Zink, Angela Aletaha, Daniel Schoneveld, Leonard Riel, Piet van Gutermann, Loriane Prior, Yeliz Nikiphorou, Elena (reumatológus) Ferraccioli, Gianfranco Schett, Georg Hyrich, Kimme L. Mueller-Ladner, Ulf Buch, Maya H. McInnes, Iain B. Heijde, Désirée van der Laar, Jacob M. van
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3.

001-es BibID:BIBFORM081587
Első szerző:Najm, Aurélie
Cím:EULAR points to consider for the development, evaluation and implementation of mobile health applications aiding self-management in people living with rheumatic and musculoskeletal diseases / Aurélie Najm, Elena Nikiphorou, Marie Kostine, Christophe Richez, John D. Pauling, Axel Finckh, Valentin Ritschl, Yeliz Prior, Petra Balázová, Simon Stones, Zoltan Szekanecz, Annamaria Iagnocco, Sofia Ramiro, Francisca Sivera, Maxime Dougados, Loreto Carmona, Gerd Burmester, Dieter Wiek, Laure Gossec, Francis Berenbaum
Dátum:2019
Megjegyzések:Background Mobile health applications (apps) are available to enable people with rheumatic and musculoskeletal diseases (RMDs) to better self-manage their health. However, guidance on the development and evaluation of such apps is lacking. Objectives The objective of this EULAR task force was to establish points to consider (PtC) for the development, evaluation and implementation of apps for self-management of RMDs. Methods A systematic literature review of app content and development strategies was conducted, followed by patient focus group and an online survey. Based on this information and along with task force expert opinion, PtC were formulated in a face-to-face meeting by a multidisciplinary task force panel of experts, including two patient research partners. The level of agreement among the panel in regard to each PtC was established by anonymous online voting. Results Three overarching principles and 10 PtC were formulated. Three PtC are related to patient safety, considered as a critical issue by the panel. Three are related to relevance of the content and functionalities. The requirement for transparency around app development and funding sources, along with involvement of relevant health professionals, were also raised. Ease of app access across ages and abilities was highlighted, in addition to considering the cost benefit of apps from the outset. The level of agreement was from 8.8 to 9.9 out of 10. Conclusion These EULAR PtC provide guidance on important aspects that should be considered for the development, evaluation and implementation of existing and new apps.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Rheumatic and Musculoskeletal Diseases. - 5 (2019), p. 1-7. -
További szerzők:Nikiphorou, Elena (reumatológus) Kostine, Marie Richez, Christophe Pauling, John D. Finckh, Axel Ritschl, Valentin Prior, Yeliz Balázová, Petra Stones, Simon Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Iagnocco, Annamaria Ramiro, Sofia Sivera, Francisca Dougados, Maxime Carmona, Loreto Burmester, Gerd R. Wiek, Dieter Gossec, Laure Berenbaum, Francis
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4.

001-es BibID:BIBFORM075616
035-os BibID:(cikkazonosító)197
Első szerző:Nikiphorou, Elena (reumatológus)
Cím:Editorial : comorbidity burden in rheumatic diseases / Elena Nikiphorou, Michael T. Nurmohamed, Zoltan Szekanecz
Dátum:2018
ISSN:2296-858X
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
comorbidity
multimorbidity
rheumatic diseases
rheumatoid arthritis (RA)
treat-to-target
Megjelenés:Frontiers in Medicine. - 5 (2018), p. 1-3. -
További szerzők:Nurmohamed, Michael T. Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus)
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5.

001-es BibID:BIBFORM103086
035-os BibID:(cikkazonosító)e002518 (WoS)000838782000001 (Scopus)85135547779
Első szerző:Ovseiko, Pavel V.
Cím:Gender equity in academic rheumatology, current status and potential for improvement : a cross-sectional study to inform an EULAR task force / Pavel V. Ovseiko, Laure Gossec, Laura Andreoli, Uta Kiltz, Leonieke van Mens, Neelam Hassan, Marike van der Leeden, Heidi J., Siddle, Alessia Alunno, Iain B. McInnes, Nemanja S. Damjanov, Florence Apparailly, Caroline Ospelt, Irene E. van der Horst-Bruinsma, Elena Nikiphorou, Katie L. Druce, Zoltán Szekanecz, Alexandre Sepriano, Tadej Avcin, George Bertsias, Georg Schett, Anne-Maree Keenan, Linda H. Pololi, Laura C. Coates
Dátum:2022
ISSN:2056-5933
Megjegyzések:Objectives Evidence on the current status of gender equity in academic rheumatology in Europe and potential for its improvement is limited. The EULAR convened a task force to obtain empirical evidence on the potential unmet need for support of female rheumatologists, health professionals and non-clinical scientists in academic rheumatology. Methods This cross-sectional study comprised three web-based surveys conducted in 2020 among: (1) EULAR scientific member society leaders, (2) EULAR and Emerging EULAR Network (EMEUNET) members and (3) EULAR Council members. Statistics were descriptive with significance testing for male/female responses assessed by chi(2) test and t-test. Results Data from EULAR scientific member societies in 13 countries indicated that there were disproportionately fewer women in academic rheumatology than in clinical rheumatology, and they tended to be under-represented in senior academic roles. From 324 responses of EULAR and EMEUNET members (24 countries), we detected no gender differences in leadership aspirations, self-efficacy in career advancement and work-life integration as well as the share of time spent on research, but there were gender differences in working hours and the levels of perceived gender discrimination and sexual harassment. There were gender differences in the ranking of 7 of 26 factors impacting career advancement and of 8 of 24 potential interventions to aid career advancement. Conclusions There are gender differences in career advancement in academic rheumatology. The study informs a EULAR task force developing a framework of potential interventions to accelerate gender-equitable career advancement in academic rheumatology.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Gender equity
Career advancement
Academic rheumatology
EULAR
Megjelenés:RMD Open. - 8 : 2 (2022), p. 1-11. -
További szerzők:Gossec, Laure Andreoli, Laura Kiltz, Uta Mens, Leonieke van Hassan, Neelam Leeden, Marike van der Siddle, Heidi J. Alunno, Alessia McInnes, Iain B. Damjanov, Nemanja S. Apparailly, Florence Ospelt, Caroline Horst-Bruinsma, Irene E. van der Nikiphorou, Elena (reumatológus) Druce, Katie L. Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Sepriano, Alexandre Avcin, Tadej Bertsias, George Schett, Georg Keenan, Anne-Maree Pololi, Linda H. Coates, Laura C.
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