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001-es BibID:	BIBFORM051089
Első szerző:	Dienes Beatrix (élettanász, molekuláris biológus)
Cím:	Wavelet transforms based novel methods to detect calcium sparks and embers / Dienes B., Szabó L. Zs., Vincze J., Csernoch L., Szentesi P.
Dátum:	2010
Tárgyszavak:	Orvostudományok Elméleti orvostudományok idézhető absztrakt
Megjelenés:	Acta Physiologica Hungarica 97 : Suppl. (2010), p. 435. -
További szerzők:	Szabó László Zsolt Vincze J. Csernoch László (1961-) (élettanász) Szentesi Péter (1967-) (élettanász)
Pályázati támogatás:	K75604 OTKA NK78398 OTKA ETT 186-09 Egyéb
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM096629
Első szerző:	Szabó László Zsolt
Cím:	An image analyser program written in MATLAB to detect and analyse calcium sparks / Szabó László Zsolt, Dienes Beatrix, Csernoch László
Dátum:	2007
Megjegyzések:	In muscle cells calcium sparks and embers are elementary intracellular events of excitation-contraction coupling. Study of these events is achieved through confocal microscopy based on fluorescent dyes. The large collection of images in an experiment need automated procedures to detect, analyse and store characteristic data of these elementary events. We developed a computer program written in MATLAB to solve these problems for striated muscle cell experiments. The program is capable of analysing a large number of line scan (time-space) images, to detect the morphology and to computer the characteristic spatial and temporal parameters of the events. The detection of the events on an image is automatic, permitting also interactive user intervention. The parameters of calcium sparks are stored in a relational database allowing the retrieval of data for statistical analysis of large image sets.
Tárgyszavak:	Orvostudományok Elméleti orvostudományok előadáskivonat könyvrészlet calcium sparks confocal microscopy biological image analysis MATLAB
Megjelenés:	Proceedings of the 7th international conference on applied informatics (Volume 1.) / szerk. Kovács Emőd, Olajos Péter, Tómács Tibor. - p. 155-162.
További szerzők:	Dienes Beatrix (1972-) (élettanász, molekuláris biológus) Csernoch László (1961-) (élettanász)
Internet cím:	Szerző által megadott URL Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM015999
Első szerző:	Szabó László Zsolt
Cím:	Improved spark and ember detection using stationary wavelet transforms / Szabo L. Z., Vincze J., Csernoch L., Szentesi P.
Dátum:	2010
ISSN:	0022-5193
Megjegyzések:	Calcium sparks and embers are localized intracellular events of calcium release in muscle cells studied frequently by confocal microscopy using line-scan imaging The large quantity of images and large number of events require automatic detection procedures based on signal processing methods. In the past decades these methods were based on thresholding procedures Although, recently, wavelet transforms were also introduced, they have not become widespread We have implemented a set of algorithms based on one- and two-dimensional versions of the a trous wavelet transform The algorithms were used to perform spike filtering, denoising and detection procedures Due to the dependence of the algorithms on user adjustable parameters, their effect on the efficiency of the algorithm was studied in detail We give methods to avoid false positive detections which are the consequence of the background noise in confocal images In order to establish the efficiency and reliability of the algorithms, various tests were performed on artificial and experimental images. Spark parameters (amplitude, full width-at-half maximum) calculated using the traditional and the wavelet methods were compared We found that the latter method is capable of identifying more events with better accuracy on experimental images Furthermore, we extended the wavelet-based transform from calcium sparks to long-lasting small-amplitude events as calcium embers The method not only solved their automatic detection but enabled the identification of events with small amplitude that otherwise escaped the eye. rendering the determination of their characteristic parameters more accurate.
Tárgyszavak:	Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Journal of Theoretical Biology. - 264 : 4 (2010), p. 1279-1292. -
További szerzők:	Vincze János (1988-) (orvos) Csernoch László (1961-) (élettanász) Szentesi Péter (1967-) (élettanász)
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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