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001-es BibID:	BIBFORM031844
035-os BibID:	PMID:10573488
Első szerző:	Al-Mohammad, A.
Cím:	Can the surface electrocardiogram be used to predict myocardial viability? / A. Al-Mohammad, M. Y. Norton, I. R. Mahy, J. C. Patel, A. E. Welch, P. Mikecz, S. Walton
Dátum:	1999
ISSN:	1355-6037
Megjegyzések:	OBJECTIVE: To investigate whether QRS morphology on the surface ECG can be used to predict myocardial viability. DESIGN: ECGs of 58 patients with left ventricular impairment undergoing positron emission tomography (PET) were studied. (13)N-Ammonia (NH(3)) and (18)F-fluorodeoxyglucose (FDG) were the perfusion and the metabolic markers, respectively. The myocardium is scarred when the uptake of both markers is reduced (matched defect). Reduced NH(3) uptake with persistent FDG uptake (mismatched defect) represents hibernating myocardium. First, the relation between pathological Q waves and myocardial scarring was investigated. Second, the significance of QR and QS complexes in predicting hibernating myocardium was determined. RESULTS: As a marker of matched PET defects, Q waves were specific (79%) but not sensitive (41%), with a 77% positive predictive accuracy and a poor (43%) negative predictive accuracy. The mean size of the matched PET defect associated with Q waves was 20% of the left ventricle. This was not significantly different from the size of the matched PET defects associated with no Q waves (18%). Among the regions associated with Q waves on the ECG, there were 16 regions with QR pattern (group A) and 23 regions with QS pattern (group B). The incidence of mismatched PET defects was 19% of group A and 30% of group B (NS). CONCLUSIONS: Q waves are specific but not sensitive markers of matched defects representing scarred myocardium. Q waves followed by R waves are not more likely to be associated with hibernating myocardium than QS complexes.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban külföldön készült közlemény
Megjelenés:	Heart. - 82 : 6 (1999), p. 663-667. -
További szerzők:	Norton, M. Mahy, I. R. Patel, J. Welch, A. E. Walton, S. Mikecz Pál (1956-) (vegyész)
Internet cím:	Szerző által megadott URL Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM031905
035-os BibID:	WOS:000077624500023
Első szerző:	Welch, A. E.
Cím:	Attenuation correction in PET using consistency information / Welch, A., Campbell, C., Clackdoyle, R., Natterer, F., Hudson, M., Bromiley, A., Mikecz, P., Chillcot, F., Dodd, M., Hopwood, P., Craib, S., Gullberg, G. T., Sharp, P.
Dátum:	1998
ISSN:	0018-9499
Megjegyzések:	In this study the authors use the consistency conditions of the Radon transform to aid attenuation correction in PET. The conditions are used both for estimating the parameters of a uniform elliptical attenuation distribution (without any transmission measurements) and for correcting for patient motion between the transmission and emission acquisitions. The results show that, for a uniform elliptical attenuation distribution, the reconstructed count densities obtained using attenuation correction based on the consistency conditions are within 1% of the true values. The method is shown to be fairly tolerant to the effects of photon counting statistics and to small non-uniformities in the attenuation distribution (such as skull attenuation). The results also show that the consistency conditions may be useful in correcting for patient motion. The method is shown to effectively compensate for shifts in two dimensions using both simulated and experimental data
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban külföldön készült közlemény
Megjelenés:	IEEE transactions on nuclear science. - 45 : 6 (1998), p. 3134-3141. -
További szerzők:	Campbell, Cabrina Clackdoyle, R. Natterer, F. Hudson, M. Bromiley, A. Chillcot, F. Dodd, Maurice Hopwood, P. Craib, S. Gullberg, G. T. Sharp, Peter F. Mikecz Pál (1956-) (vegyész)
Internet cím:	DOI
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