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001-es BibID:	BIBFORM010606
Első szerző:	Dankó Katalin (belgyógyász, allergológus és klinikai immunológus)
Cím:	Paraneoplastic myopathy / Katalin Dankó, Andrea Ponyi, Andrew P. Molnar, Csilla András, Tamas Constantin
Dátum:	2009
ISSN:	1040-8711 (Print)
Megjegyzések:	It has been recognized for some time now, that compared with the normal population, patients with idiopathic inflammatory myopathies (IIM) live with an increased risk of developing malignancy. In the majority of these patients, cancer-associated myositis appears to have some paraneoplastic features. The aim of the present review is to describe new data that explain the connection between myositis and malignant diseases, as well as to highlight its value in the current management of these patients. RECENT FINDINGS: Antigen expressions and patterns shared by regenerating muscle and cancers raise questions about whether myositis cases without clinically observable cancer may represent a fully successful antitumor immune response with bystander damage to regenerating muscle. The discovery of anti-155/140 autoantibody may aid in the better diagnosis of adult IIM patients with a higher risk of malignancy. It also may help the better understanding of paraneoplastic myositis. SUMMARY: Cancer-associated myositis differs from primary myositis in many aspects. Prognosis and life-expectancy are determined by the underlying malignancy. Therefore, patient-specific examinations for detection of an underlying cancer are important in the management of patients. Recent clinical findings and new possibilities in immunoserological testing may result in the elaboration of an evidence-based recommendation for cancer screening programs in patients with IIM in the future.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Current Opinion in Rheumatology. - 21 : 6 (2009), p. 594-598. -
További szerzők:	Ponyi Andrea Molnár Andrew P. András Csilla (1961-) (onkológus szakorvos) Constantin Tamás
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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001-es BibID:	BIBFORM073042
Első szerző:	Rider, Lisa G.
Cím:	Myositis registries and biorepositories / Rider Lisa G., Dankó Katalin, Miller Frederick W.
Dátum:	2014
ISSN:	1040-8711
Megjegyzések:	PURPOSE OF REVIEW:Clinical registries and biorepositories have proven extremely useful in many studies of diseases, especially rare diseases. Given their rarity and diversity, the idiopathic inflammatory myopathies, or myositis syndromes, have benefited from individual researchers' collections of cohorts of patients. Major efforts are being made to establish large registries and biorepositories that will allow many additional studies to be performed that were not possible before. Here, we describe the registries developed by investigators and patient support groups that are currently available for collaborative research purposes.RECENT FINDINGS:We have identified 46 myositis research registries, including many with biorepositories, which have been developed for a wide variety of purposes and have resulted in great advances in understanding the range of phenotypes, clinical presentations, risk factors, pathogenic mechanisms, outcome assessment, therapeutic responses, and prognoses. These are now available for collaborative use to undertake additional studies. Two myositis patient registries have been developed for research, and myositis patient support groups maintain demographic registries with large numbers of patients available to be contacted for potential research participation.SUMMARY:Investigator-initiated myositis research registries and biorepositories have proven extremely useful in understanding many aspects of these rare and diverse autoimmune diseases. These registries and biorepositories, in addition to those developed by myositis patient support groups, deserve continued support to maintain the momentum in this field as they offer major opportunities to improve understanding of the pathogenesis and treatment of these diseases in cost-effective ways.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban biorepository dermatomyositis idiopathic inflammatory myopathies inclusion body myositis juvenile dermatomyositis myositis autoantibody natural history phenotype polymyositis registry
Megjelenés:	Current Opinion In Rheumatology 26 : 6 (2014), p. 724-741. -
További szerzők:	Dankó Katalin (1952-2021) (belgyógyász, allergológus és klinikai immunológus) Miller, Frederick W.
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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