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1.
001-es BibID:
BIBFORM073208
035-os BibID:
(WoS)000398387200006 (Scopus)85019025865
Első szerző:
Aggarwal, Rohit
Cím:
2016 American College of Rheumatology/European League Against Rheumatism criteria for minimal, moderate, and major clinical response in adult dermatomyositis and polymyositis / Rohit Aggarwal, Lisa G. Rider, Nicolino Ruperto, Nastaran Bayat, Brian Erman, Brian M. Feldman, Chester V. Oddis, Anthony A. Amato, Hector Chinoy, Robert G. Cooper, Maryam Dastmalchi, David Fiorentino, David Isenberg, James D. Katz, Andrew Mammen, Marianne de Visser, Steven R. Ytterberg, Ingrid E. Lundberg, Lorinda Chung, Katalin Danko, Ignacio García-De la Torre, Yeong Wook Song, Luca Villa, Mariangela Rinaldi, Howard Rockette, Peter A. Lachenbruch, Frederick W. Miller, Jiri Vencovsky, International Myositis Assessment and Clinical Studies Group, Paediatric Rheumatology International Trials Organisation
Dátum:
2017
ISSN:
0003-4967
Megjegyzések:
To develop response criteria for adult dermatomyositis (DM) and polymyositis (PM). Expert surveys, logistic regression, and conjoint analysis were used to develop 287 definitions using core set measures. Myositis experts rated greater improvement among multiple pairwise scenarios in conjoint analysis surveys, where different levels of improvement in 2 core set measures were presented. The PAPRIKA (Potentially All Pairwise Rankings of All Possible Alternatives) method determined the relative weights of core set measures and conjoint analysis definitions. The performance characteristics of the definitions were evaluated on patient profiles using expert consensus (gold standard) and were validated using data from a clinical trial. The nominal group technique was used to reach consensus. Consensus was reached for a conjoint analysis-based continuous model using absolute per cent change in core set measures (physician, patient, and extramuscular global activity, muscle strength, Health Assessment Questionnaire, and muscle enzyme levels). A total improvement score (range 0-100), determined by summing scores for each core set measure, was based on improvement in and relative weight of each core set measure. Thresholds for minimal, moderate, and major improvement were ?20, ?40, and ?60 points in the total improvement score. The same criteria were chosen for juvenile DM, with different improvement thresholds. Sensitivity and specificity in DM/PM patient cohorts were 85% and 92%, 90% and 96%, and 92% and 98% for minimal, moderate, and major improvement, respectively. Definitions were validated in the clinical trial analysis for differentiating the physician rating of improvement (p<0.001). The response criteria for adult DM/PM consisted of the conjoint analysis model based on absolute per cent change in 6 core set measures, with thresholds for minimal, moderate, and major improvement.
Tárgyszavak:
Orvostudományok
Klinikai orvostudományok
idegen nyelvű folyóiratközlemény külföldi lapban
Dermatomyositis
Polymyositis
Treatment
Megjelenés:
Annals Of The Rheumatic Diseases. - 76 : 5 (2017), p. 792-801. -
További szerzők:
Rider, Lisa G.
Ruperto, Nicolino
Bayat, Nastaran
Erman, Brian
Feldman, Brian M.
Oddis, Chester V.
Amato, Anthony A.
Chinoy, Hector
Cooper, Robert G.
Dastmalchi, Maryam
Fiorentino, David
Isenberg, David A.
Katz, James D.
Mammen, Andrew
Visser, Marianne de
Ytterberg, Steven R.
Lundberg, Ingrid
Chung, Lorinda
Dankó Katalin (1952-2021) (belgyógyász, allergológus és klinikai immunológus)
Torre, Ignacio García-De la
Song, Yeong Wook
Villa, Luca
Rinaldi, Mariangela
Rockette, Howard
Lachenbruch, Peter A.
Miller, Frederick W.
Vencovsky, Jiri
International Myositis Assessment and Clinical Studies Group
Paediatric Rheumatology International Trials Organisation (PRINTO)
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
2.
001-es BibID:
BIBFORM073210
Első szerző:
Aggarwal, Rohit
Cím:
2016 American College of Rheumatology/European League Against Rheumatism Criteria for Minimal, Moderate, and Major Clinical Response in Adult Dermatomyositis and Polymyositis: An International Myositis Assessment and Clinical Studies Group/Paediatric Rheu / Rohit Aggarwal, Lisa G. Rider, Nicolino Ruperto, Nastaran Bayat, Brian Erman, Brian M. Feldman, Chester V. Oddis, Anthony A. Amato, Hector Chinoy, Robert G. Cooper, Maryam Dastmalchi, David Fiorentino, David Isenberg, James D. Katz, Andrew Mammen, Marianne de Visser, Steven R. Ytterberg, Ingrid E. Lundberg, Lorinda Chung, Katalin Danko, Ignacio García-De la Torre, Yeong Wook Song, Luca Villa, Mariangela Rinaldi, Howard Rockette, Peter A. Lachenbruch, Frederick W. Miller, Jiri Vencovsky, International Myositis Assessment and Clinical Studies Group, Paediatric Rheumatology International Trials Organisation
Dátum:
2017
ISSN:
2326-5191
Megjegyzések:
OBJECTIVE:To develop response criteria for adult dermatomyositis (DM) and polymyositis (PM).METHODS:Expert surveys, logistic regression, and conjoint analysis were used to develop 287 definitions using core set measures. Myositis experts rated greater improvement among multiple pairwise scenarios in conjoint analysis surveys, where different levels of improvement in 2 core set measures were presented. The PAPRIKA (Potentially All Pairwise Rankings of All Possible Alternatives) method determined the relative weights of core set measures and conjoint analysis definitions. The performance characteristics of the definitions were evaluated on patient profiles using expert consensus (gold standard) and were validated using data from a clinical trial. The nominal group technique was used to reach consensus.RESULTS:Consensus was reached for a conjoint analysis-based continuous model using absolute percent change in core set measures (physician, patient, and extramuscular global activity, muscle strength, Health Assessment Questionnaire, and muscle enzyme levels). A total improvement score (range 0-100), determined by summing scores for each core set measure, was based on improvement in and relative weight of each core set measure. Thresholds for minimal, moderate, and major improvement were ?20, ?40, and ?60 points in the total improvement score. The same criteria were chosen for juvenile DM, with different improvement thresholds. Sensitivity and specificity in DM/PM patient cohorts were 85% and 92%, 90% and 96%, and 92% and 98% for minimal, moderate, and major improvement, respectively. Definitions were validated in the clinical trial analysis for differentiating the physician rating of improvement (P?<?0.001).CONCLUSION:The response criteria for adult DM/PM consisted of the conjoint analysis model based on absolute percent change in 6 core set measures, with thresholds for minimal, moderate, and major improvement.
Tárgyszavak:
Orvostudományok
Klinikai orvostudományok
idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:
Arthritis & Rheumatology 69 : 5 (2017), p. 898-910. -
További szerzők:
Rider, Lisa G.
Ruperto, Nicolino
Bayat, Nastaran
Erman, Brian
Feldman, Brian M.
Oddis, Chester V.
Amato, Anthony A.
Chinoy, Hector
Cooper, Robert G.
Dastmalchi, Maryam
Fiorentino, David
Isenberg, David A.
Katz, James D.
Mammen, Andrew
Visser, Marianne de
Ytterberg, Steven R.
Lundberg, Ingrid
Chung, Lorinda
Dankó Katalin (1952-2021) (belgyógyász, allergológus és klinikai immunológus)
Torre, Ignacio García-De la
Song, Yeong Wook
Villa, Luca
Rinaldi, Mariangela
Rockette, Howard
Lachenbruch, Peter A.
Miller, Frederick W.
Vencovsky, Jiri
International Myositis Assessment and Clinical Studies Group
Paediatric Rheumatology International Trials Organisation (PRINTO)
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
3.
001-es BibID:
BIBFORM073197
Első szerző:
Rider, Lisa G.
Cím:
2016 ACR-EULAR adult dermatomyositis and polymyositis and juvenile dermatomyositis response criteria-methodological aspects / Lisa G. Rider, Nicolino Ruperto, Angela Pistorio, Brian Erman, Nastaran Bayat, Peter A. Lachenbruch, Howard Rockette, Brian M. Feldman, Adam M. Huber, Paul Hansen, Chester V. Oddis, Ingrid E. Lundberg, Anthony A. Amato, Hector Chinoy, Robert G. Cooper, Lorinda Chung, Katalin Danko, David Fiorentino, Ignacio García-De la Torre, Ann M. Reed, Yeong Wook Song, Rolando Cimaz, Rubén J. Cuttica, Clarissa A. Pilkington, Alberto Martini, Janjaap van der Net, Susan Maillard, Frederick W. Miller, Jiri Vencovsky, Rohit Aggarwal, International Myositis Assessment and Clinical Studies Group, Paediatric Rheumatology International Trials Organisation
Dátum:
2017
ISSN:
1462-0324
Megjegyzések:
OBJECTIVE:The objective was to describe the methodology used to develop new response criteria for adult DM/PM and JDM.METHODS:Patient profiles from prospective natural history data and clinical trials were rated by myositis specialists to develop consensus gold-standard ratings of minimal, moderate and major improvement. Experts completed a survey regarding clinically meaningful improvement in the core set measures (CSM) and a conjoint-analysis survey (using 1000Minds software) to derive relative weights of CSM and candidate definitions. Six types of candidate definitions for response criteria were derived using survey results, logistic regression, conjoint analysis, application of conjoint-analysis weights to CSM and published definitions. Sensitivity, specificity and area under the curve were defined for candidate criteria using consensus patient profile data, and selected definitions were validated using clinical trial data.RESULTS:Myositis specialists defined the degree of clinically meaningful improvement in CSM for minimal, moderate and major improvement. The conjoint-analysis survey established the relative weights of CSM, with muscle strength and Physician Global Activity as most important. Many candidate definitions showed excellent sensitivity, specificity and area under the curve in the consensus profiles. Trial validation showed that a number of candidate criteria differentiated between treatment groups. Top candidate criteria definitions were presented at the consensus conference.CONCLUSION:Consensus methodology, with definitions tested on patient profiles and validated using clinical trials, led to 18 definitions for adult PM/DM and 14 for JDM as excellent candidates for consideration in the final consensus on new response criteria for myositis.
Tárgyszavak:
Orvostudományok
Klinikai orvostudományok
idegen nyelvű folyóiratközlemény külföldi lapban
1000Minds software
conjoint analysis
dermatomyositis
hybrid measure
juvenile dermatomyositis
outcome assessment
polymyositis
response criteria
Megjelenés:
Rheumatology 56 : 11 (2017), p. 1884-1893. -
További szerzők:
Ruperto, Nicolino
Pistorio, Angela
Erman, Brian
Bayat, Nastaran
Lachenbruch, Peter A.
Rockette, Howard
Feldman, Brian M.
Huber, Adam M.
Hansen, Paul
Oddis, Chester V.
Lundberg, Ingrid
Amato, Anthony A.
Chinoy, Hector
Cooper, Robert G.
Chung, Lorinda
Dankó Katalin (1952-2021) (belgyógyász, allergológus és klinikai immunológus)
Fiorentino, David
Torre, Ignacio García-De la
Reed, Ann M.
Song, Yeong Wook
Cimaz, Rolando
Cuttica, Ruben
Pilkington, Clarissa
Martini, Alberto
Net, Janjaap van der
Maillard, Susan
Miller, Frederick W.
Vencovsky, Jiri
Aggarwal, Rohit
International Myositis Assessment and Clinical Studies Group
Paediatric Rheumatology International Trials Organisation (PRINTO)
Internet cím:
Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:
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