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001-es BibID:	BIBFORM054217
035-os BibID:	PMID: 10938896
Első szerző:	Káplár Miklós (belgyógyász, diabetológus)
Cím:	Increased leukocyte-platelet adhesion in chronic myeloproliferative disorders with high platelet counts / M. Kaplar, J. Kappelmayer, A. Kiss, K. Szabo, M. Udvardy
Dátum:	2000
ISSN:	0953-7104
Megjegyzések:	The heterophilic adhesions between monocytes and platelets may result in the modification of both platelet and monocyte function. This mutual modification includes a greater activation of platelets with increased production of PDGF and other metabolites as well as an enhanced tissue factor expression of monocytes with greater activity in the circulation. The heterophilic aggregation has been well documented during extracorporal circulation, haemodialysis and in diabetic retinopathy. Here we provide evidence that there is significant increase of monocyte-platelet aggregates in disorders associated with high platelet counts, such as chronic myeloproliferative disorders. The presence of these heterophilic aggregates may contribute to the vascular complications observed frequently in polycythaemia vera and essential thrombocythaemia.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Platelets. - 11 : 3 (2000), p. 183-184. -
További szerzők:	Kappelmayer János (1960-) (laboratóriumi szakorvos) Kiss Attila (1942-) (belgyógyász, haematológus) Szabó K. Udvardy Miklós (1947-) (belgyógyász, haematológus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM034352
Első szerző:	Rejtő László (belgyógyász, haematológus)
Cím:	Use of a platelet filter test in patients with thrombocytosis / László Rejtő, Ágota Schlammadinger, Pál László, Attila Kiss, Béla Telek, Zoltán Boda
Dátum:	2000
ISSN:	0953-7104
Megjegyzések:	In the differential diagnosis of primary and secondary thrombocytosis platelet function tests may play an important role. We examined the applicability of a platelet filter test (shear-dependent platelet aggregation) as a tool, to differentiate primary thrombocytosis (cases with myeloproliferative disorders) from secondary (reactive) thrombocytosis. The test was carried out in 53 patients suffering from myeloproliferative disorders associated with primary thrombocytosis and in 21 patients with other diseases complicated by secondary thrombocytosis. Using citrate as anticoagulant, the sensitivity of the O'Brien's test proved to be 77.1%, and its specificity 94.4%. Using heparin as anticoagulant the sensitivity and specificity of the test were found to be also reliably high. Based on these studies we suggest the use of the O'Brien's filterometer as a screening test in the differential diagnosis in patients with elevated platelet count. In the case of normal results, the causes of reactive thrombocytosis should be clarified first, while with abnormal results, haematological examination of the patients should be performed.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Platelets. - 11 : 1 (2000), p. 38-42. -
További szerzők:	Schlammadinger Ágota (1971-) (belgyógyász, haematológus) László Pál (belgyógyász) Kiss Attila (1942-) (belgyógyász, haematológus) Telek Béla (1948-) (belgyógyász, haematológus) Boda Zoltán (1947-) (belgyógyász, haematologus, klinikai onkológus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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