CCL

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001-es BibID:BIBFORM040488
Első szerző:Sziklai István (fül-orr-gégész)
Cím:Electrochemical composition of the cochlear fluids in the early experimental hydrops : preliminary results / Sziklai I., Horner K. C., Ferrary E., Sterkers O., Amiel C.
Dátum:1989
ISSN:0001-6489
Megjegyzések:The composition of endolymph and perilymph was studied in the guinea pig cochlea after 2 and 6 weeks of blockage of the vestibular aqueduct in an experimental model of hydrops. Compound action potential was monitored several times in the observation period. The endocochlear potential was measured and the endolymph was sampled at the first and third turns of the scala media. The Na, K, and Cl concentrations were determined in nanolitre aliquots of endolymph and of perilymph, the latter sampled from the basal scala vestibuli. After 2 weeks, no change in endolymphatic electrochemical composition was observed. After 6 weeks, endocochlear potential was decreased by 25% at both cochlear turns; K concentration was decreased in endolymph of the basal turn and Cl concentration was decreased in both turns; the calculated osmolality (Na + K + Cl) was decreased in both turns. These results indicate that the blockage of the vestibular aqueduct induced early auditory dysfunction whereas alterations of the electrochemical composition of endolymph occurred later after a time lag of more than 2 and less than 6 weeks.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Acta Oto-Laryngologica. - 107 : 5-6 (1989), p. 371-374. -
További szerzők:Horner, K. C. Ferrary, Evelyne Sterkers, Olivier Amiel, Claude
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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2.

001-es BibID:BIBFORM040609
Első szerző:Sziklai István (fül-orr-gégész)
Cím:Vasopressin entry into the inner ear fluids of the rat / I. Sziklai, E. Ferrary, O. Sterkers, C. Amiel
Dátum:1987
ISSN:0378-5955
Megjegyzések:The entry of arginine-vasopressin (AVP) and sucrose into cochlear endolymph, perilymph of scala vestibuli (PLV), perilymph of scala tympani (PLT), and cisternal cerebrospinal fluid (CSF) was studied, in anesthetized rats, after the administration into the cerebral lateral ventricle of a 10 microliter solution containing the radioactive tracers. Both tracers were detected in PLV, PLT, and CSF but not in endolymph. Monoexponential decay curves were calculated for PLV, PLT, and CSF, and for each tracer no difference was found between the regression lines calculated for the different fluids. These results indicate that (i) injection into the cerebral lateral ventricle is a useful tool to study the permeability of the cochlear epithelium to different solutes and (ii) no specific transport system exists for AVP across the cochlear epithelium, suggesting that AVP may exert its effect via the perilymphatic side of the stria vascularis.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Hearing Research. - 29 : 2-3 (1987), p. 245-250. -
További szerzők:Ferrary, Evelyne Sterkers, Olivier Amiel, Claude
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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