CCL

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1.

001-es BibID:BIBFORM032363
Első szerző:Csépány Tünde (neurológus, pszichiáter)
Cím:MRI findings in central nervous system systemic lupus erythematosus are associated with immunoserological parameters and hypertension / Csepany, T., Bereczki, D., Kollar, J., Sikula, J., Kiss, E., Csiba, L.
Dátum:2003
Megjegyzések:Involvement of the brain is one of the most important complications of systemic lupus erythematosus (SLE). To investigate the correlation between abnormal cranial MRI findings and age, duration of SLE, neuropsychiatric (NP) manifestations, hypertensive status, and the presence of antiphospholipid antibodies (PA) in patients with SLE we evaluated the MRI results of 81 SLE patients in nine NP clinical subgroups.Immunoserological status was described by the presence of lupus anticoagulant (LA), and anticardiolipin antibodies (aCL). The MRI findings were categorized as normal [41], cerebral atrophy [15], small subcortical hyperintensity [7], and infarct larger than 10mm [18]. Mean age differed among the clinical subgroups (ANOVA, p = 0.002), whereas there was no age difference among the subgroups based on MRI and immunoserological results. Patients with hypertension (33/81) were a mean of 6 years older at the time of examination (p = 0.033) and had stroke more frequently, than normotensive ones (p = 0.0015). MRI abnormalities were more frequent in patients with LA positivity (p < 0.01) than in those without these antibodies, and in the hypertensive than in the normotensive subgroup (p = 0.00041). The presence of PA was associated with abnormal MRI even after controlling for the effect of age and hypertensive status (p = 0.011). In our study the MRI findings in central nervous system SLE were independent of the age of patients and the age at the diagnosis of SLE, and were not influenced by the duration of SLE; however, they were associated with immunoserological parameters and hypertension.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
multiple sclerosis
autoimmunity
iron
prolactin
ferritin
Megjelenés:Journal of Neurology. - 250 : 11 (2003), p. 1348-1354. -
További szerzők:Bereczki Dániel (1960-) (neurológus) Kollár József (1950-) (radiológus) Sikula Judit (1954-) (radiológus) Kiss Emese (1960-) (belgyógyász, immunológus) Csiba László (1952-) (neurológus, pszichiáter)
Internet cím:DOI
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2.

001-es BibID:BIBFORM015604
035-os BibID:15778910
Első szerző:Schulte-Altedorneburg, Gernot
Cím:Measuring carotid artery stenosis-comparison of postmortem arteriograms with theplanimetric gold standard / Schulte-Altedorneburg Gernot, Droste Dirk W., Kollar Jozef, Beyna Torsten, Felszeghy Szabolcs, Modis Laszlo, Hegedus Csaba, Ringelstein E. Bernd, Csiba Laszlo
Dátum:2005
ISSN:0340-5354 (Linking)
Megjegyzések:Five different calliper methods for assessing the degree of carotidartery stenosis and visual estimation ("eyeballing") of postmortem carotidarteriograms were compared with the planimetric gold standard of the areareduction at the site of the stenosis. METHODS: During autopsy 53 carotidspecimens were removed in toto from 31 neurological patients. Carotid arterieswere ligated and redistended to a physiological degree for standardisedthree-plane arteriography. Afterwards, the entire specimen was filled with anembedding medium under the same conditions and sectioned. Slices at the site ofstenoses were histologically processed. Computerised planimetric analysis of thelumen area reduction was performed and compared with the arteriographic findings.Arteriograms were evaluated by two independent observers by means of linearCommon Carotid Artery (CC), the European Carotid Surgery Trial (ECST) and theNorth American Symptomatic Carotid Endarterectomy Trial (NASCET), and squaredmeasurements (NASCET2, ECST2) after applying the pi r2 function. Further, threeindependent observers performed eyeballing of the degree of stenosis from thepostmortem arteriographies. RESULTS: Planimetry was carried out in 29 internalcarotid artery (ICA) and 17 common carotid artery (CCA) stenoses ranging from 8.5to 100%. The smallest mean differences of the degree of stenosis in % betweenplanimetry and arteriography were -0.5 and 0.6%. The narrowest 95 %-limits ofagreement covered a range of +/-24.1 and 26.3% of stenoses, and the highestcorrelation coefficients were both 0.9 for the CC and ECST2 techniques,respectively. By eyeballing, the degree of stenosis was underestimated by 13.5 to15.8% on average. The narrowest limits of agreement between two observers foreyeballing covered a range of 35%. CONCLUSION: Three-plane arteriography has onlya moderate accuracy and reproducibility in detecting and measuring carotid arterystenosis independent of the technique of measurement used.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Aged
Angiography/methods
Carotid Artery, Common/pathology/*radiography
Carotid Artery, External/pathology/*radiography
Carotid Artery, Internal/pathology/*radiography
Carotid Stenosis/pathology/*radiography
Female
Humans
egyetemen (Magyarországon) készült közlemény
Male
Megjelenés:The Journal of Neurology. - 252 : 5 (2005), p. 575-582. -
További szerzők:Droste, Dirk W. Kollár József (1950-) (radiológus) Beyna, Torsten Felszeghy Szabolcs Béla (1972-) (fogorvos, anatómus, kötőszövetbiológus) Módis László (1939-) (anatómus, kötőszövetbiológus) Hegedűs Csaba (1953-) (fogszakorvos) Ringelstein, E. Bernd Csiba László (1952-) (neurológus, pszichiáter)
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elektronikus változat
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3.

001-es BibID:BIBFORM042398
Első szerző:Settakis, George
Cím:Acetazolamide as a vasodilatory stimulus in cerebrovascular diseases and in conditions affecting the cerebral vasculature / Settakis, G., Molnar, C., Kerenyi, L., Kollar, J., Legemate, D., Csiba, L., Fulesdi, B.
Dátum:2003
ISSN:1351-5101
Megjegyzések:Pathologic processes affecting the brain vessels may damage cerebral vasodilatory capacity. Early detection of cerebral dysfunction plays an important role in the prevention of cerebrovascular diseases. In recent decades acetazolamide (AZ) has frequently been used for this purpose. In the present work the mechanism of action and the previous studies are reviewed. The authors conclude that AZ tests are useful in cerebrovascular research. Further investigations are recommended to prove how impaired reserve capacity and reactivity influence the stroke risk in patients and whether these tests may indicate therapeutic interventions.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:European Journal Of Neurology. - 10 : 6 (2003), p. 609-620. -
További szerzők:Molnár Csilla (1962-) (aneszteziológus) Kerényi Levente Kollár József (1950-) (radiológus) Legemate, D. Csiba László (1952-) (neurológus, pszichiáter) Fülesdi Béla (1961-) (aneszteziológus)
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