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001-es BibID:BIBFORM016922
035-os BibID:(WoS)000283477500003 (Scopus)77956231195
Első szerző:Csiba László (neurológus, pszichiáter)
Cím:Visualization of the ischemic core on native human brain slices by potassium staining method / Csiba Laszlo, Farkas Szabolcs, Kollar Jozsef, Berenyi Ervin, Nagy Katalin, Bereczki Daniel
Dátum:2010
ISSN:0165-0270
Megjegyzések:The potassium staining method is based on the formation of potassiumcobaltnitrite crystals after the treatment by sodium cobaltnitrite ofbrain tissue. The degree of staining correlates with the distinctpotassium content of infracted and non-infarcted brain areas.The aim of the present study was to prove that potassium stainingtechnique is a reliable method for localization of ischemic core onnative whole hemisphere cryosections of stroke patients. Furthermore,potassium stained sections have been compated with appropriatepostmortem MRI images of respective brains.Brains of stroke patients were removed within 24 h after death andpostmortem MRI scanning was performed. Horizontal cryosections offrozen brains were taken and potassium staining was performed. Usingthe stained whole hemisphere sections as "map" tissue sampling has beenmade in order to determine water and potassium content.Potassium content of infarcted samples was significantly decreased incomparison with intact regions (0.7346 +/- 0.2142 mg/L and 1.928 +/-0.447 mg/L, respectively, p<0.01) (mean values +/-SD). Water content ofaffected areas (expressed in percents) has been found to be abovenon-infarcted regions (81.657% +/- 4.07 and 72.96% +/- 6.37,respectively, p<0.01).According to our results the potassium staining method of human wholehemisphere brain sections reliably differentiates focal ischemic areasfrom intact brain regions. In conclusion, the postmortem examination ofischemic brain could be started with making the potassium map ofinfarcted whole hemisphere cryosections providing guidance for targetedtissue sampling and base of comparison for further examinations. (C)2010 Elsevier B.V. All rights reserved.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Journal of Neuroscience Methods. - 192 : 1 (2010), p. 17-21. -
További szerzők:Farkas Szabolcs (1983-) (orvos) Kollár József (1950-) (radiológus) Berényi Ervin (1964-) (radiológus) Nagy Katalin (1960-) (orvosdiagnosztikai laboratóriumi analitikus) Bereczki Dániel (1960-) (neurológus)
Internet cím:DOI
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001-es BibID:BIBFORM015756
Első szerző:Emri Miklós (fizikus)
Cím:The importance of MRI-PET registration in clinical routine / M. Emri, G. Opposits, L. Trón, Á. Klekner, L. Novák, J. Kollár, L. Bognár, E. Berényi
Dátum:2007
Megjegyzések:Registered images produced by MRI based multi-modality image processing are essential tools of diagnostic and surgical planning of neurological and neurosurgical diseases. The aim of this study was to investigate how fused images produced by various MRI (T1, T2, fMRI, DTI, MRS) and PET (FDG, Metionine) data can be used in clinical routine. Material and methods: In our study the complex multi-modality tomographic data sets of 6 patients (3 glioblastoma, 2 oligoastrocitóma és 1 pilocitás astrocitoma) were used. For the image registration as well as the production of 2D- and 3D fused images free, commercial and in-house developed software were utilized. Result: We found that our images significantly assisted clinicians in preparing therapeutic and surgical plans. Optimizing the established software and automatizing image registration tasks needs further development.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
Megjelenés:Nuclear Medicine Review. - 10 : 1 (2007), p. 59. -
További szerzők:Opposits Gábor (1974-) (fizikus, szoftver fejlesztő) Trón Lajos (1941-) (biofizikus) Klekner Álmos (1970-) (idegsebész) Novák László (1964-) (idegsebész) Kollár József (1950-) (radiológus) Bognár László (1958-) (idegsebész, gyermekidegsebész) Berényi Ervin (1964-) (radiológus)
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