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001-es BibID:	BIBFORM020658
Első szerző:	László F. János (fizikus)
Cím:	Daily exposure to inhomogeneous static magnetic field significantly reduces blood glucose level in diabetic mice / János F. László, Judit Szilvási, Anett Fényi, Andrea Szalai, Klára Gyires, Róbert Pórszász
Dátum:	2011
Megjegyzések:	The present study was designed to reveal, whether the 30 min daily full body exposure of mice to aninhomogeneous static magnetic field (SMF) has a statistically significant effect on diabetic neuropathy.Materials and methods: Three different doses (100, 150, or 200 mg/kg) of streptozotocin (STZ) were administeredintraperitoneally in groups of mice to induce diabetes. Body weight, blood glucose level and the nociceptive temperaturethreshold of mice were monitored for a period of 12 weeks. The group treated with 200 mg/kg i.p. STZ produced manifestdiabetic neuropathy. Results were compared to non-treated (no SMF, no STZ) and SMF exposure without STZ-treatmentgroup (SMF, no STZ) group. The inhomogeneous SMF was in the range of 2.8?476.7 mT peak-to-peak magnetic flux density.Results: Whereas SMF exposure did not seem to affect body weight and nociceptive temperature threshold, it statisticallysignificantly (p50.001) reduced blood glucose level in the 200 mg/kg STZ (n?6) group.Conclusions: Daily SMF exposure repeated for several weeks is protective against the development of high blood glucoselevel in diabetic mice.
Tárgyszavak:	Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban neuropathy diabetes neuropathia diabetica static magnetic field (SMF) mouse streptozotocin (STZ)
Megjelenés:	International Journal of Radiation Biology. - 87 : 1 (2011), p. 36-45. -
További szerzők:	Ujhelyi Judit Ágnes (1984-) (farmakológus) Fényi Anett Szalai Andrea (1968-) (analitikus) Gyires Klára Pórszász Róbert (1965-) (farmakológus, klinikai farmakológus)
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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