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001-es BibID:BIBFORM038652
Első szerző:Alberth Márta (fogszakorvos)
Cím:Significance of oral Candida infections in children with cancer / Alberth M., Majoros L., Kovalecz G., Borbás E., Szegedi I., Márton I. J., Kiss C.
Dátum:2006
ISSN:1219-4956
Megjegyzések:Candidiasis is common in children with cancer, particularly during periods of severe immunosuppression and neutropenia. Our aim was to study the microbiological changes in the oral cavity of children with newly diagnosed cancer. The study group consisted of 30 consecutive children and adolescents, 16 with acute lymphoblastic leukemia and 14 with solid tumors. Oral cultures to detect fungi and bacteria were conducted for all patients before treatment, during and after neutropenic episodes. In 23 patients developing fever simultaneous throat, urine and blood sampling was carried out. No pathogens were found in the cultures taken before the outset (30 cultures) or after recovery from (30 cultures) the neutropenic episodes. In the 45 oral cultures taken during the neutropenic episodes 38 (84.4%) proved positive. Fungi were the most frequently isolated oral pathogens: 33/38 yeast and 6/38 bacterial infections were identified. There was no association between the underlying malignancy and the occurrence of the positive cultures. Of the 30 patients, all 23 (76.7%) who have developed moderate-to-severe neutropenia, developed oral fungal colonization or clinically obvious fungal infection at least on one occasion during the study. In addition to oral samples, fungi were identified in 9/23 pharyngeal swabs, 6/23 urine and 1/23 blood cultures. The initial fungal pathogen was exclusively (33/33) Candida albicans. In extended severe neutropenic states, C. albicans was replaced by non-albicans species (C. kefyr, C. lusitaniae, C. sake, C. tropicalis) in 5 patients between 4 to 6 days of the neutropenic episodes. Four of the nonalbicans Candida strains were resistant to azole-type antifungal agents. Neutropenic episodes of children with cancer are associated with an increased risk of developing oral and even systemic infections with C. albicans that can be replaced by azole-resistant nonalbicans strains in prolonged neutropenia contributing to morbidity of these patients.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Pathology and Oncology Research. - 12 : 4 (2006), p. 237-241. -
További szerzők:Majoros László (1966-) (szakorvos, klinikai mikrobiológus) Kovalecz Gabriella (1973-) (fogszakorvos) Borbás Emese Szegedi István (1969-) (hematológus, onkológus, nefrológus) Márton Ildikó (1954-) (fogszakorvos) Kiss Csongor (1956-) (hematológus, onkológus)
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2.

001-es BibID:BIBFORM052860
Első szerző:Szabó Béla (orvos)
Cím:Studies on the possible aetiological role of different Candida species in pathogenesis of dentine caries by monitoring the calcium release from tooth particles / Béla Szabó, László Majoros, Erzsébet Papp-Falusi, Zsuzsanna Szabó, Judit Szabó, Ildikó Márton, Barna Kelentey
Dátum:2014
Megjegyzések:An in vitro model has been developed for study of cariogenic potential of different Candida species. Slices were prepared from the root of extracted healthy teeth. These disks were covered with inert material, only the central hole, i.e. the root canal dentin surface remained uncovered. These preparates with free root dentin surfaces were incubated in Sabouraud medium in the presence of six-six Candida albicans, Candida glabrata, Candida tropicalis, Candida krusei, Candida inconspicua and Candida norvegensis strains. The calcium release was detected for 15 days. Two types of release could be distinguished. C. albicans deliberated calcium more aggressively (type "A" curve), while other Candidas were characterized by less expressed calcium releasing capacity (type "B" curve). Curves type "A" and "B" were divided into four steps in order to characterize more precisely the different dynamics of calcium release. Analyses of the different steps also suggested the more aggressive behaviour of C. albicans. Our results indicate that in addition to cariogenic role of different bacteria, fungi may also actively take part in the dentinal caries progress.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény hazai lapban
Candida
caries
dentine
Megjelenés:Acta Microbiologica Immunologica Hungarica. - 61 : 1 (2014), p. 11-17. -
További szerzők:Majoros László (1966-) (szakorvos, klinikai mikrobiológus) Pappné Falusi Erzsébet Szabó Zsuzsanna (1973-) (biológus, biológia-kémia szakos középiskolai tanár) Szabó Judit (1963-) (szakorvos, klinikai mikrobiológus) Márton Ildikó (1954-) (fogszakorvos) Kelentey Barna (1959-) (fogszakorvos)
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3.

001-es BibID:BIBFORM008950
Első szerző:Varga István (fogszakorvos)
Cím:Differences in killing activity of caspofungin and paradoxical growth between Candida albicans and C. krusei clinical isolates in different media / Varga I., Sóczó G., Kardos G., Kemény-Beke A., Kelentey B., Márton I., Majoros L.
Dátum:2009
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
caspofungin
Candida
Megjelenés:Journal of Chemotherapy. - 21 : 1 (2009), p. 36-41. -
További szerzők:Sóczó Georgina (1979-) Kardos Gábor (1974-) (szakorvos, klinikai mikrobiológus) Kemény-Beke Ádám (1968-2021) (szemész) Kelentey Barna (1959-) (fogszakorvos) Márton Ildikó (1954-) (fogszakorvos) Majoros László (1966-) (szakorvos, klinikai mikrobiológus)
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