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001-es BibID:	BIBFORM101443
035-os BibID:	(WoS)000787144100001 (Scopus)85128863628
Első szerző:	Balázs Gergely (csecsemő- és gyermekgyógyász, neonatológus)
Cím:	Incidence, predictors of success and outcome of LISA in very preterm infants / Balazs Gergely, Balajthy Andras, Riszter Magdolna, Kovacs Tamas, Szabo Tamas, Belteki Gusztav, Balla Gyorgy
Dátum:	2022
ISSN:	8755-6863
Megjegyzések:	Objectives The aim of this study was to examine the success rate of less invasive surfactant administration (LISA), to identify early predictive factors for the outcome of LISA, and to compare neonatal outcomes between the LISA failure group and the group of infants who were successfully treated with LISA. Design A retrospective cohort study. Patients Infants born at less than 33 weeks of gestation (n = 158) and treated with LISA for respiratory distress syndrome. Results LISA was successful in 86 cases (54.4%); 72 preterm infants (45.6%) needed additional surfactant therapy and/or mechanical ventilation in the first 72 h (LISA failure). In a multivariate logistic regression analysis, six independent predictors of LISA success were identified: core temperature at the time of admission (adjusted odds ratio (OR): 3.56), dose of poractant alfa (<200 mg/kg; adjusted OR: 0.254), elevated C-reactive protein (>10 mg/L) at 24 h of life (adjusted OR: 0.28), highest respiratory severity score (RSS) during the first hour of life or at the time of LISA (adjusted OR: 0.463), maternal age (adjusted OR: 0.923), and birth weight (adjusted OR: 1.003). The receiver operating curve created by using the identified factors indicates good predictive power with an area under the curve of 0.85. LISA failure was associated with a substantially higher risk of complications. Conclusion LISA success can be predicted by variables available before the intervention. Failure of LISA is relatively frequent event in very preterm infants and is associated with adverse outcomes. Prevention of hypothermia during early stabilization and appropriate dosing of surfactant may increase LISA success rates and improve patient outcome.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk respiratory distress syndrome in premature infants continuous positive airway pressure surfactant
Megjelenés:	Pediatric Pulmonology. - 57 : 7 (2022), p. 1751-1759. -
További szerzők:	Balajthy András (1988-) (általános orvos) Riszter Magdolna (1973-) (csecsemő és gyermekgyógyász, neonatológus) Kovács Tamás (1970-) (csecsemő és gyermekgyógyász, neonatológus) Szabó Tamás (1968-) (gyermekgyógyász) Bélteki Gusztáv (1970-) (csecsemő és gyermekgyógyász, neonatológus) Balla György (1953-) (csecsemő és gyermekgyógyász, neonatológus)
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001-es BibID:	BIBFORM056948
Első szerző:	Mogyorósy Gábor (csecsemő- és gyermekgyógyász, gyermekkardiológus)
Cím:	Pediatric myocarditis : a sentinel of non-cardiac chronic diseases? / Gábor Mogyorósy, Enikő Felszeghy, Tamás Kovács, Andrea Berkes, László Tóth, György Balla, Ilma Korponay-Szabó
Dátum:	2014
ISSN:	2061-1617 2061-5094
Megjegyzések:	Introduction: Although long-term outcome studies in large pediatric myocarditis/cardiomyopathy populations have been reported in literature, none of them focused on comorbidities. Methods: All children and adolescents (age <18 years) treated with myocarditis at the Department of Pediatrics, University of Debrecen, Hungary were followed. Patients suff ering from myocarditis during the period 1996-2011 were enrolled. Results: Over the 16-year period, a diagnosis of myocarditis was established in nine children. Their median age was 1.11 (0.03- 8.71) years. Three of the nine patients died. Left ventricular dilatation and ejection fraction normalized within 1-21 months in the survivors. None of the cases progressed to dilated cardiomyopathy. Regarding non-cardiac comorbidities, myocarditis or recurrent peri-myocarditis preceded the manifestation of celiac disease in two patients, while cystic fi brosis was diagnosed after the improvement of cardiac function in another, and Alström syndrome was diagnosed several years after complete recovery from myocarditis in yet another patient. Conclusion: These results suggest that manifestations of other chronic pediatric diseases may be more frequent among survivors of pediatric myocarditis. Prolonged follow-up of patients who survive myocarditis is therefore recommended not only to detect possible progression to cardiomyopathy but also to identify non-cardiac comorbidities.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény hazai lapban
Megjelenés:	Interventional Medicine and Applied Science. - 6 : 4 (2014), p. 154-159. -
További szerzők:	Felszeghy Enikő Noémi (1970-) (gyermekgyógyász) Kovács Tamás (1970-) (csecsemő és gyermekgyógyász, neonatológus) Berkes Andrea (1973-) (csecsemő- és gyermekgyógyász) Tóth László (1971-) (patológus) Balla György (1953-) (csecsemő és gyermekgyógyász, neonatológus) Korponay-Szabó Ilma (1959-) (gyermekgyógyász)
Pályázati támogatás:	TÁMOP-4.2.2.A-11/1/KONV-2012-0045 TÁMOP Gyermekgyógyászat Kutatócsoport
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