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001-es BibID:	BIBFORM042512
035-os BibID:	PMID:9138964
Első szerző:	Balogh Ádám (szülész-nőgyógyász, endokrinológus szakorvos)
Cím:	Hormone replacement therapy and prevention of osteoporosis: risk assessment and practical advice / Adam Balogh, Peter Bettembuk
Dátum:	1997
ISSN:	0004-3591
Megjegyzések:	A review of the Debrecen Regional Osteoporosis Program (DROP) in Hungary is given, with special reference to the detection of postmenopausal osteoporosis (PMOP) and its treatment by hormone replacement therapy (HRT). The new definition of osteoporosis by focusing on bone mineral density (BMD) measurements has the major advantage of practical usefulness. The algorithm of managing osteoporotic patients can be easily constructed from the result of bone densitometry as the primary diagnostic tool. The DROP serves a total population of 550,000, is equipped with a DXA bone densitometer, a bone metabolism laboratory and backed by a multidisciplinary team of clinicians from gynecology, radiology, rheumatology, internal medicine, and orthopedic surgery. In 1995 the total number of patients undergoing densitometry was 3170. In 2045 patients T scores of -1 or below were found. From this total number, 348 patients received HRT for 1 year or longer. The results of the treatment showed a positive response (i.e. no bone loss, or net gain) in 65%, while half of the 'non responders' proved in fact non compliant. The contradiction between risk assessment and early diagnosis is explained and replacing 'risk assessment' by 'selection criteria for bone densitometry' is proposed. 'Prevention of osteoporosis' is also to be replaced by 'prevention of complications', i.e. osteoporotic fractures. One of these measures is HRT. Its rational use in the prevention and treatment of osteoporosis and its relation to other treatment methods in the authors' own experience is discussed.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban külföldön készült közlemény
Megjelenés:	European journal of obstetrics, gynecology, and reproductive biology. - 71 : 2 (1997), p. 189-191. -
További szerzők:	Bettembuk Péter
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM035328
Első szerző:	Kiss Emese (belgyógyász, immunológus)
Cím:	Pregnancy in women with systemic lupus erythematosus / Emese Kiss, Harjit P. Bhattoa, Peter Bettembuk, Adam Balogh, Gyula Szegedi
Dátum:	2002
ISSN:	0301-2115
Megjegyzések:	Background: Systemic lupus erythematosus (SLE) is an autoimmune disorder which may be affected by hormonal changes, such as those of pregnancy. Women with SLE have increased adverse pregnancy outcomes. Study design: A retrospective analysis of the gynecologic and immunologic case history of 140 women with SLE and the outcome of 263 pregnancies in 99 women with SLE. Results: In patients diagnosed with SLE, the proportion of pregnancies ending with live birth at term decreased to one-third compared with three quarters in those without a diagnosis of SLE and the incidence of pre-term deliveries and spontaneous abortions increased by 6.8 and 4.7 times, respectively. When SLE was associated with secondary antiphospholipid (APL) syndrome, and lupus anticoagulant (LA) or ??2-glycoprotein antibodies were present, a further increase in the incidence of pregnancy loss was observed. Pregnancy did not cause a flare-up of SLE in all cases, the disease remained stable in about 30% of the patients. Lupus was mild in the majority of the women who carried out their pregnancy to term. We also observed mothers with active SLE who successfully carried out pregnancies to term. Conclusion: These findings accord with previous literature and should inform rheumatologists, obstetricians and neonatologists who guide patients in their reproductive decisions.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban egyetemen (Magyarországon) készült közlemény Lupus anticoagulant Pregnancy Spontaneous abortion Systemic lupus erythematosus lupus anticoagulant adult antiphospholipid syndrome article female human incidence induced abortion major clinical study pregnancy priority journal risk spontaneous abortion systemic lupus erythematosus thrombosis Adolescent Adult Aged Female Humans Lupus Erythematosus, Systemic Middle Aged Pregnancy Pregnancy Complications Pregnancy Outcome Retrospective Studies
Megjelenés:	European Journal of Obstetrics Gynecology and Reproductive Biology. - 101 : 2 (2002), p. 129-134. -
További szerzők:	Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Bettembuk Péter Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos) Szegedi Gyula (1936-2013) (belgyógyász, immunológus)
Internet cím:	Szerző által megadott URL Intézményi repozitóriumban (DEA) tárolt változat DOI
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001-es BibID:	BIBFORM042687
035-os BibID:	PMID:1773879
Első szerző:	Major Tamás (szülész-nőgyógyász)
Cím:	Chlamydia trachomatis infection among Hungarian teenage girls / Tamás Major, Ádám Balogh, Antal Borsos
Dátum:	1991
ISSN:	0301-2115
Megjegyzések:	The presence of Chlamydia trachomatis antigen was examined in 20 sexually active teenage girls by enzyme immunoassay to prove chlamydial infection. Seven of the study group showed evidence of C. trachomatis infection. The infection was more frequent in girls who used a non-barrier method for contraception and had more than four sexual partners previously. Screening for and treatment of C. trachomatis infection in high-risk teenage girls is recommended.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban egyetemen (Magyarországon) készült közlemény
Megjelenés:	European Journal of Obstetrics Gynecology and Reproductive Biology. - 42 : 3 (1991), p. 231-232. -
További szerzők:	Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos) Borsos Antal (1939-) (szülész-nőgyógyász, gyermeknőgyógyász)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM035326
Első szerző:	Móré Csaba (szülész-nőgyógyász)
Cím:	The effects of pregnancy and lactation on hormonal status and biochemical markers of bone turnover / Csaba More, Harjit P. Bhattoa, Péter Bettembuk, Ádám Balogh
Dátum:	2003
ISSN:	03012115
Megjegyzések:	Introduction: Biochemical markers of bone turnover are reliable indices for measuring changes in bone formation and bone resorption. Due to limitations in the use of bone densitometry during pregnancy biochemical markers of bone turnover provide an excellent alternative to examine the state of the skeleton during this physiologic state. Study design: We performed a prospective study in 20 women, during their first full term pregnancy until 12 months postpartum, intending to breast feed for 12 (mean, 9.1; range, 7-12) months postpartum. Morning blood and urine samples were obtained for laboratory tests: within 3 months before conception (baseline); between 22 and 24 gestational weeks; after delivery, and 6 and 12 months postpartum. Serum 25-hydroxyvitamin D (25-OH-D), parathyroid hormone (PTH), bone specific alkaline phosphatase, osteocalcin (OC), procollagen I carboxypeptides, calcium, phosphate and creatinine in addition to urine deoxypyridinoline crosslinks and calcium were measured. Results: There was no significant difference in the values of urinary calcium/creatinine and serum calcium, phosphate and 25-OH-D between the different visits during the study. In our patients there was a significant increase in PTH levels at 12 months postpartum as compared to baseline, although the mean values remained in the PTH reference range. All bone turnover markers increased during pregnancy and failed to reach baseline level even 12 months postpartum. Conclusion: The high maternal bone turnover may suggest that the calcium needed for infant growth during pregnancy and lactation may be drawn at least in part from the maternal skeleton. ?? 2002 Elsevier Science Ireland Ltd. All rights reserved.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban Bone biochemical markers Hormonal status Lactation Pregnancy 25 hydroxyvitamin D alkaline phosphatase biochemical marker deoxypyridinoline osteocalcin parathyroid hormone procollagen c proteinase adult article blood sampling bone turnover breast milk calcium blood level calcium urine level clinical article conception controlled study creatinine urine level delivery female gestational age hormone metabolism hormone urine level human laboratory test lactation normal value parathyroid hormone blood level phosphate blood level pregnancy priority journal puerperium statistical significance third trimester pregnancy urinalysis vitamin blood level Adult Alkaline Phosphatase Amino Acids Bone Remodeling Calcifediol Calcium Cohort Studies Creatinine Female Humans Lactation Osteocalcin Parathyroid Hormone Peptide Fragments Phosphates Pregnancy Procollagen Prospective Studies egyetemen (Magyarországon) készült közlemény
Megjelenés:	European Journal of Obstetrics Gynecology and Reproductive Biology. - 106 : 2 (2003), p. 209-213. -
További szerzők:	Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Bettembuk Péter Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos)
Internet cím:	Szerző által megadott URL Intézményi repozitóriumban (DEA) tárolt változat DOI
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