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1.

001-es BibID:BIBFORM042520
Első szerző:Bettembuk Péter
Cím:Csontsűrűség vizsgálata rheumatoid arthritises betegeken / Bettembuk Péter, Balogh Ádám, Szekanecz Zoltán, Szegedi Gyula, Surányi Péter
Dátum:1996
ISSN:0884-0431
Tárgyszavak:Orvostudományok Klinikai orvostudományok magyar nyelvű folyóiratközlemény hazai lapban
egyetemen (Magyarországon) készült közlemény
Megjelenés:Magyar Reumatológia. - 37 : 3 (1996), p. 140-147. -
További szerzők:Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos) Szekanecz Zoltán (1964-) (reumatológus, belgyógyász, immunológus) Szegedi Gyula (1936-2013) (belgyógyász, immunológus) Surányi Péter
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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2.

001-es BibID:BIBFORM035376
035-os BibID:WOS:000177952800624
Első szerző:Bhattoa Harjit Pal (laboratóriumi szakorvos)
Cím:Bone mineral density changes in a one year placebo controlled double blind randomized trial of hormone replacement therapy in postmenopausal systemic lupus erythematosus patient / Bhattoa, H. P., Bettembuk, P., Balogh, Á., Szegedi, Gy., Kiss, E.
Dátum:2002
ISSN:0884-0431
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
Endocrinology & Metabolism
egyetemen (Magyarországon) készült közlemény
Megjelenés:Journal of Bone and Mineral Research. Supplement. - 17 : 1 (2002), p. S272. -
További szerzők:Bettembuk Péter Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos) Szegedi Gyula (1936-2013) (belgyógyász, immunológus) Kiss Emese (1960-) (belgyógyász, immunológus)
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3.

001-es BibID:BIBFORM035327
Első szerző:Bhattoa Harjit Pal (laboratóriumi szakorvos)
Cím:Bone mineral density in women with systemic lupus erythematosus / H. P. Bhattoa, P. Bettembuk, A. Balogh, G. Szegedi, E. Kiss
Dátum:2002
ISSN:0770-3198
Megjegyzések:The aim of this cross-sectional study was to determine the prevalence of reduced bone mineral density (BMD) in a group of female SLE patients and to identify factors predictive of reduced BMD. Femoral neck (FN) and lumbar spine (LS) dual-energy X-ray absorptiometry results wer evaluated in 79 pre- and postmenopausal women with SLE aged (mean, range) 49 (22-73) years). Variables evaluated were disease duration, SLEDAI, current and cumulative corticosteroid dose, Steinbrocker's functional classification, use of immunosuppressive agents, and history of fracture due to minor trauma. A T-score of ?ë♯n 1.0 was found in 61.9% at the LS and 48.3% at the FN, and 18 (23.7%) patients belonged to the category of osteoporosis at LS, compared to only three (5.4%) patients at FN. A statistical difference (P = 0.014) was found when comparing LS BMD in pre- and postmenopausal patients. LS BMD had a significant correlation with daily and cumulative steroid dose (P = 0.016 and 0.031, respectively). There was a significant difference in LS BMD between the daily steroid dose group receiving ?ë♯n 7.5 and those receiving > 7.5. mg/day (P = 0.008), and also in FN BMD comparing groups on 0 and > 7.5 mg/day (P = 0.022). There was significant difference in LS and FN BMD between patients in Steinbrocker classes I and III (P = 0.016 and 0.005, respectively). No significant correlation was found in either subgroup between BMD and other studied parameters. We concluded that the prevalence of reduced bone mass at LS is pronounced among postmenopausal women with SLE, in those with a high Steinbrocker functional classification and those on a high daily steroid dose. Therefore, these patients should be considered as a high-risk group deserving regular spinal BMD scans and therapy in time to prevent vertebral fractures.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
egyetemen (Magyarországon) készült közlemény
Bone mineral density
Female
Glucocorticoids
Osteoporosis
Systemic lupus erythematosus
corticosteroid
immunosuppressive agent
adult
aged
article
bone density
bone mass
bone mineral
bone scintiscanning
controlled study
correlation analysis
disease classification
disease duration
dose response
dual energy X ray absorptiometry
female
femur neck
high risk patient
human
lumbar spine
osteoporosis
postmenopause
prediction
premenopause
prevalence
priority journal
scoring system
systemic lupus erythematosus
vertebra fracture
age distribution
cohort analysis
comparative study
cross-sectional study
hospitalization
Hungary
middle aged
physiology
probability
radiodensitometry
risk assessment
risk factor
Adrenal Cortex Hormones
Adult
Age Distribution
Aged
Bone Density
Cohort Studies
Comparative Study
Cross-Sectional Studies
Densitometry, X-Ray
Female
Human
Hungary
Lupus Erythematosus, Systemic
Middle Age
Osteoporosis
Prevalence
Probability
Risk Assessment
Risk Factors
Severity of Illness Index
Support, Non-U.S. Gov't
Humans
Middle Aged
Megjelenés:Clinical Rheumatology. - 21 : 2 (2002), p. 135-141. -
További szerzők:Bettembuk Péter Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos) Szegedi Gyula (1936-2013) (belgyógyász, immunológus) Kiss Emese (1960-) (belgyógyász, immunológus)
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4.

001-es BibID:BIBFORM035324
Első szerző:Bhattoa Harjit Pal (laboratóriumi szakorvos)
Cím:The effect of 1-year transdermal estrogen replacement therapy on bone mineral density and biochemical markers of bone turnover in osteopenic postmenopausal systemic lupus erythematosus patients : a randomized, double-blind, placebo-controlled trial / H. P. Bhattoa, P. Bettembuk, A. Balogh, Gy. Szegedi, E. Kiss
Dátum:2004
ISSN:0937941X
Megjegyzések:We studied the effect of 1-year transdermal estrogen replacement therapy (ERT) on bone mineral density (BMD) and biochemical markers of bone turnover in osteopenic postmenopausal systemic lupus erythematosus (SLE) patients in a randomized, double-blind, placebo-controlled trial. SLE patients were randomly allocated to treatment (estradiol; 50 ??g transdermal 17??-estradiol; n = 15) or placebo (n = 17) group. Both groups received 5 mg continuous oral medroxyprogesterone acetate, 500 mg calcium and 400 IU vitamin D3, L1-L4 spine (LS), left femur and total hip BMD were measured at baseline and at 6 and 12 months. Serum osteocalcin (OC) and degradation products of C-terminal telopeptides of type-I collagen (CTx) levels were measured at baseline and 3, 6, 9, and 12 months. There was a significant difference in the percentage change of LS BMD at 6 months between the two groups (103.24 ?? 3.74% (estradiol group) vs 98.99 ?? 3.11% (placebo group); P < 0.005). There was a significant decrease within the estradiol group in the CTx levels between baseline and all subsequent visits (P < 0.05). There was no significant difference in SLE disease activity index, Systemic Lupus International Collaborating Clinics/American College of Rheumatology (ACR) damage index and corticosteroid dose during the study period, Transdermal estradiol may prevent bone loss in postmenopausal SLE women at the lumbar spine and femur, with no increase in disease activity among postmenopausal SLE women receiving transdermal ERT. The high dropout rate (8/15) leads us to the conclusion that efficacy of HRT in a high-risk group such as SLE women can be attained only in a small number of patients, provided all inclusion/exclusion criteria are strictly adhered to.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Biochemical markers of bone turnover
Bone mineral density
Osteopenia
Postmenopausal Systemic lupus erythematosus
Transdermal estrogen replacement therapy
biological marker
calcium
carboxy terminal telopeptide
collagen type 1
corticosteroid
estradiol
medroxyprogesterone acetate
osteocalcin
placebo
vitamin D
adult
aged
article
bone density
bone mineral
bone turnover
carboxy terminal sequence
clinical trial
controlled clinical trial
controlled study
disease activity
double blind procedure
drug effect
drug efficacy
estrogen therapy
female
femur
hip
human
lumbar spine
medical society
osteolysis
osteopenia
postmenopause
priority journal
prophylaxis
protein blood level
randomization
randomized controlled trial
systemic lupus erythematosus
Administration, Cutaneous
Adult
Aged
Biological Markers
Bone Density
Bone Remodeling
Double-Blind Method
Estradiol
Estrogen Replacement Therapy
Female
Femur Neck
Hip Joint
Humans
Lumbar Vertebrae
Lupus Erythematosus, Systemic
Middle Aged
Osteoporosis, Postmenopausal
egyetemen (Magyarországon) készült közlemény
Megjelenés:Osteoporosis International. - 15 : 5 (2004), p. 396-404. -
További szerzők:Bettembuk Péter Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos) Szegedi Gyula (1936-2013) (belgyógyász, immunológus) Kiss Emese (1960-) (belgyógyász, immunológus)
Internet cím:Szerző által megadott URL
Intézményi repozitóriumban (DEA) tárolt változat
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5.

001-es BibID:BIBFORM035328
Első szerző:Kiss Emese (belgyógyász, immunológus)
Cím:Pregnancy in women with systemic lupus erythematosus / Emese Kiss, Harjit P. Bhattoa, Peter Bettembuk, Adam Balogh, Gyula Szegedi
Dátum:2002
ISSN:0301-2115
Megjegyzések:Background: Systemic lupus erythematosus (SLE) is an autoimmune disorder which may be affected by hormonal changes, such as those of pregnancy. Women with SLE have increased adverse pregnancy outcomes. Study design: A retrospective analysis of the gynecologic and immunologic case history of 140 women with SLE and the outcome of 263 pregnancies in 99 women with SLE. Results: In patients diagnosed with SLE, the proportion of pregnancies ending with live birth at term decreased to one-third compared with three quarters in those without a diagnosis of SLE and the incidence of pre-term deliveries and spontaneous abortions increased by 6.8 and 4.7 times, respectively. When SLE was associated with secondary antiphospholipid (APL) syndrome, and lupus anticoagulant (LA) or ??2-glycoprotein antibodies were present, a further increase in the incidence of pregnancy loss was observed. Pregnancy did not cause a flare-up of SLE in all cases, the disease remained stable in about 30% of the patients. Lupus was mild in the majority of the women who carried out their pregnancy to term. We also observed mothers with active SLE who successfully carried out pregnancies to term. Conclusion: These findings accord with previous literature and should inform rheumatologists, obstetricians and neonatologists who guide patients in their reproductive decisions.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
egyetemen (Magyarországon) készült közlemény
Lupus anticoagulant
Pregnancy
Spontaneous abortion
Systemic lupus erythematosus
lupus anticoagulant
adult
antiphospholipid syndrome
article
female
human
incidence
induced abortion
major clinical study
pregnancy
priority journal
risk
spontaneous abortion
systemic lupus erythematosus
thrombosis
Adolescent
Adult
Aged
Female
Humans
Lupus Erythematosus, Systemic
Middle Aged
Pregnancy
Pregnancy Complications
Pregnancy Outcome
Retrospective Studies
Megjelenés:European Journal of Obstetrics Gynecology and Reproductive Biology. - 101 : 2 (2002), p. 129-134. -
További szerzők:Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Bettembuk Péter Balogh Ádám (1940-) (szülész-nőgyógyász, endokrinológus szakorvos) Szegedi Gyula (1936-2013) (belgyógyász, immunológus)
Internet cím:Szerző által megadott URL
Intézményi repozitóriumban (DEA) tárolt változat
DOI
Borító:
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