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001-es BibID:	BIBFORM049529
Első szerző:	Berczi Csaba (urológus, sebész, onkológus)
Cím:	A Technetium-99m-sestamibi és a Technetium-99m-pertechnetate scintigraphia jelentősége a primer hyperparathyreosis preoperatív diagnosztikájában / Berczi Csaba, Mezősi Emese, Galuska László, Varga József, Bajnok László, Lukács Géza, Balázs György
Dátum:	1999
Tárgyszavak:	Orvostudományok Klinikai orvostudományok magyar nyelvű folyóiratközlemény hazai lapban primer hyperparathyreosis lokalizációs vizsgálatok izotóp scintographia parathyreoidectomia
Megjelenés:	Magyar Radiológia. - 73 : 1 (1999), p. 13-17. -
További szerzők:	Mezősi Emese Galuska László (1946-) (belgyógyász, izotópdiagnoszta) Varga József (1955-) (fizikus) Bajnok László (1961-) (belgyógyász) Lukács Géza (1941-) (sebész) Balázs György (1933-) (sebész)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	BIBFORM033184
Első szerző:	Berczi Csaba (urológus, sebész, onkológus)
Cím:	Technetium-99m-sestamibi/pertechnetate subtraction scintigraphy vs ultrasonography for preoperative localization in primary hyperparathyroidism / C. Berczi, E. Mezősi, L. Galuska, J. Varga, L. Bajnok, G. Lukács, G. Balázs
Dátum:	2002
Megjegyzések:	A prospective study was performed to evaluate the efficacy of technetium-99m-sestamibi and technetium-99m-pertechnetate subtraction scanning and US for imaging parathyroid glands in primary hyperparathyroidism. Sixty-three patients were surgically treated for primary hyperparathyroidism (HPT). Preoperative scintigraphy and US were performed in all cases. Bilateral neck exploration was carried out on each patient. Results of radionuclide studies and US were compared with surgical and histological findings. In 57 patients with primary HPT the radionuclide scanning gave true-positive results. Four false-negative and two false-positive scintigrams were obtained. The sensitivity and the positive predictive value (PPV) of scintigraphy were 93 and 97%, respectively. Forty-one cases were correctly localized by the US. Seventeen US results were false negative and five were false positive. The sensitivity and the PPV for US were 71 and 89%, respectively. There was a statistically significant difference between the sensitivity of the scintigraphy compared with the US ( p=0.001). Sensitivities of radionuclide scans and US were higher for adenomas (100 and 83%) than for hyperplastic glands (75 and 40%). The sensitivity of technetium-99m-sestamibi and technetium-99m-pertechnetate subtraction scintigraphy was significantly higher compared with US. This sensitive method could help surgeons in performing a rapid and directed parathyroidectomy.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk egyetemen (Magyarországon) készült közlemény
Megjelenés:	European Radiology. - 12 : 3 (2002), p. 605-609. -
További szerzők:	Mezősi Emese Galuska László (1946-) (belgyógyász, izotópdiagnoszta) Varga József (1955-) (fizikus) Bajnok László (1961-) (belgyógyász) Lukács Géza (1941-) (sebész) Balázs György (1933-) (sebész)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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001-es BibID:	BIBFORM033124
035-os BibID:	PMID:16025395
Első szerző:	Győry Ferenc (kardiológus)
Cím:	Establishment of the hu-PBL-SCID mouse model for the investigation of thyroid cancer / F. Győry, E. Mezősi, Sz. Szakáll, L. Bajnok, E. Varga, A. Borbély, A. Gazdag, I. Juhász, G. Lukács, E. V. Nagy
Dátum:	2005
Megjegyzések:	New experimental models of human neoplastic diseases attempt to mimic the human environment that fostered the development of disease in cancer patients. The aim of the present study was to establish a human lymphocyte-engrafted, severe combined immunodeficient (hu-PBL-SCID) mouse model to investigate thyroid cancer and to evaluate the potential use of this model for cancer immunotherapy. Thyroid neoplastic tissues were obtained from ten patients (one follicular adenoma, five papillary, one follicular, one anaplastic and two medullary cancers). One 8 x 4 x 3 millimeter sample from each tumor was cut into two pieces of identical size and transplanted into two SCID mice. In each case, one of the two mice was injected intraperitoneally with lymphocytes from the same tumor patient for the reconstitution of the human immune system (Group A), while the other animal received no lymphocytes (Group B). The engraftment of the tumors was successful in all cases. The growth rate was highly dependent on the histological type. When histologies were compared before implantation and after the removal of the implants, the characters of the tumors proved to be unchanged, except one case where an anaplastic cancer arose from a papillary tumor. Macrophages were present in all but one papillary cancer. All differentiated thyroid cancers were infiltrated by T and B lymphocytes. Lymphocytes and macrophages disappeared from 19/20 grafts by week 16. However, in one case from group A lymphocytes were detected four months after the transplantation. In another case from group A, one papillary cancer spontaneously decreased in size and disappeared. Before implantation, HLA-DR expression was detected in every papillary cancer. HLA-DR expression in the grafts was not seen in 3/5 cases by week 16. In conclusion, an animal model has been established for the investigation of human thyroid cancer, by which the analysis of anti-tumor immunity, as a postulate of immune therapy, may be possible.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban egyetemen (Magyarországon) készült közlemény
Megjelenés:	Experimental and clinical endocrinology and diabetes 113 : 7 (2005), p. 359-364. -
További szerzők:	Mezősi Emese Szakáll Szabolcs (1970-) jr. Bajnok László (1961-) (belgyógyász) Varga E. Borbély A. Gazdag Annamária (1979-) (belgyógyász) Juhász István (1956-) (bőrgyógyász, bőrsebész, kozmetológus, klinikai onkológus) Lukács Géza (1941-) (sebész) Nagy Endre V. (1957-) (belgyógyász, endokrinológus)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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