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1.

001-es BibID:BIBFORM091005
Első szerző:Antonenko, Kateryna
Cím:Sex-related differences in risk factors, type of treatment received and outcomes in patients with atrial fibrillation and acute stroke: Results from the RAF-study (Early Recurrence and Cerebral Bleeding in Patients with Acute Ischemic Stroke and Atrial Fibrillation) / Kateryna Antonenko, Maurizio Paciaroni, Giancarlo Agnelli, Nicola Falocci, Cecilia Becattini, Simona Marcheselli, Christina Rueckert, Alessandro Pezzini, Loris Poli, Alessandro Padovani, Laszló Csiba, Lilla Szabó, Sung-Il Sohn, Tiziana Tassinari, Azmil H. Abdul-Rahim, Patrik Michel, Maria Cordier, Peter Vanacker, Suzette Remillard, Andrea Alberti, Michele Venti, Monica Acciarresi, Cataldo D'Amore, Umberto Scoditti, Licia Denti, Giovanni Orlandi, Alberto Chiti, Gino Gialdini, Paolo Bovi, Monica Carletti, Alberto Rigatelli, Jukka Putaala, Turgut Tatlisumak, Luca Masotti, Gianni Lorenzini, Rossana Tassi, Francesca Guideri, Giuseppe Martini, Georgios Tsivgoulis, Kostantinos Vadikolias, Sokratis G. Papageorgiou, Francesco Corea, Massimo Del Sette, Walter Ageno, Maria Luisa De Lodovici, Giorgio Bono, Antonio Baldi, Sebastiano D'Anna, Simona Sacco, Antonio Carolei, Cindy Tiseo, Davide Imberti, Dorjan Zabzuni, Boris Doronin, Vera Volodina, Domenico Consoli, Franco Galati, Alessio Pieroni, Danilo Toni, Serena Monaco, Mario M. Baronello, Kristian Barlinn, Lars-Peder Pallesen, Jessica Kepplinger, Ulf Bodechtel, Johannes Gerber, Dirk Deleu, Gayane Melikyan, Faisal Ibrahim, Naveed Akhtar, Maria G. Mosconi, Kennedy R. Lees, Valeria Caso
Dátum:2016
ISSN:2396-9873 2396-9881
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:European Stroke Journal. - 2 : 1 (2016), p. 46-53. -
További szerzők:Paciaroni, Maurizio Agnelli, Giancarlo Falocci, Nicola Becattini, Cecilia Marcheselli, Simona Rueckert, Christina Pezzini, Alessandro Poli, Loris Padovani, Alessandro Csiba László (1952-) (neurológus, pszichiáter) Szabó Lilla (1976-) (egyetemi tanár) Sohn, Sung-Il Tassinari, Tiziana Abdul-Rahim, Azmil H. Michel, Patrik Cordier, Maria Vanacker, Peter Remillard, Suzette Alberti, Andrea Venti, Michele Acciarresi, Monica D'Amore, Cataldo Scoditti, Umberto Denti, Licia Orlandi, Giovanni Chiti, Alberto Gialdini, Gino Bovi, Paolo Carletti, Monica Rigatelli, Alberto Putaala, Jukka Tatlisumak, Turgut Masotti, Luca Lorenzini, Gianni Tassi, Rossana Guideri, Francesca Martini, Giuseppe Tsivgoulis, Georgios Vadikolias, Kostantinos Papageorgiou, Sokratis G. Corea, Francesco Del Sette, Massimo Ageno, Walter De Lodovici, Maria Luisa Bono, Giorgio Baldi, Antonio D'Anna, Sebastiano Sacco, Simona Carolei, Antonio Tiseo, Cindy Imberti, Davide Zabzuni, Dorjan Doronin, Boris Volodina, Vera Consoli, Domenico Galati, Franco Pieroni, Alessio Toni, Danilo Monaco, Serena Baronello, Mario Maimone Barlinn, Kristian Pallesen, Lars-Peder Kepplinger, Jessica Bodechtel, Ulf Gerber, Johannes Deleu, Dirk Melikyan, Gayane Ibrahim, Faisal Akhtar, Naveed Mosconi, Maria Giulia Lees, Kennedy R. Caso, Valeria
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2.

001-es BibID:BIBFORM079827
035-os BibID:(cikkazonosító)AS24-060
Első szerző:Árokszállási Tamás (neurológus)
Cím:Hemostasis biomarkers in the prognosis of non-traumatic intracerebral hemorrhage / T. Arokszallasi, Z. Bagoly, K. Fekete, I. Fekete, I. Szegedi, M. Andrejkovics, J. Toth, L. Csiba
Dátum:2019
Megjegyzések:Background and Aims: Non-traumatic intracerebral hemorrhage (ICH) accounts for 10?15% of all strokes and results in higher rate of mortality as compared to ischemic strokes. In the IRONHEART study we aimed to find potential hemostasis biomarkers with prognostic value in patients with ICH. Methods: In this prospective, observational study, 183 acute stroke patients and 140 healthy controls were included. Patients were grouped: 51 primary ICH patients (PICH), 118 acute ischemic stroke patients who underwent thrombolysis without hemorrhagic events (AIS), 13 patients with AIS who suffered hemorrhagic complications after intravenous thrombolysis (AIS-ICH). On admission, CT angiography, detailed clinical and laboratory investigations were performed. The following hemostasis measurements were carried out from blood samples: hemostasis screening tests, von Willebrand factor (VWF) antigen, factor XIII (FXIII), plasminogen and a2 antiplasmin activity, D-dimer. Patients were followed for 90 days, long term outcomes were defined using the modified Rankin Scale. Results: VWF level was significantly higher in all patient groups as compared to controls. VWF levels were significantly higher in patients with worse long-term outcomes (mRS>3) in all patient cohorts. FXIII activity was significantly elevated in the PICH group as compared to controls and to both AIS groups. FXIII activity in the lowest quartile was associated with a significant risk of mortality in the PICH group (OR: 9.9; 95%CI:1.6- 61.6, p ? 0.015). Among fibrinolytic markers, only D-dimer showed association with worse long-term outcomes (mRS>3). Conclusions: VWF antigen, FXIII activity and D-dimer could serve as biomarkers of long-term outcomes in PICH patients.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
haemorrhage
Megjelenés:European Stroke Journal. - 4 : Suppl. 1 (2019), p. 449. -
További szerzők:Bagoly Zsuzsa (1978-) (orvos) Fekete Klára (1978-) (neurológus) Fekete István (1951-) (neurológus, pszichiáter) Szegedi István (1992-) (orvos) Andrejkovics Mónika (1967-) (klinikai szakpszichológus, neuropszichológus, pszichoterapeuta) Tóth J. Csiba László (1952-) (neurológus, pszichiáter)
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3.

001-es BibID:BIBFORM106777
035-os BibID:(scopus)85103595509 (wos)000635996200001
Első szerző:de Jonge, Jeroen C.
Cím:Regulatory delays in a multinational clinical stroke trial / de Jonge Jeroen C., Reinink Hendrik, Colam Bridget, Alpers Iris, Ciccone Alfonso, Csiba Laszlo, Korv Janika, Kurkowska-Jastrzebska Iwona, Macleod Malcolm R., Ntaios George, Thomalla Götz, Bath Philip M., van der Worp H. Bart
Dátum:2021
ISSN:2396-9873 2396-9881
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:European Stroke Journal. - 6 : 2 (2021), p. 120-127. -
További szerzők:Reinink, Hendrik Colam, Bridget Alpers, Iris Ciccone, Alfonso Csiba László (1952-) (neurológus, pszichiáter) Kõrv, Janika Kurkowska-Jastrzebska, Iwona Macleod, Malcolm R. Ntaios, George Thomalla, Götz Bath, Philip M. van der Worp, H. Bart
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4.

001-es BibID:BIBFORM079829
035-os BibID:(cikkazonosító)AS05-056
Első szerző:Fekete Klára (neurológus)
Cím:Predictors of long-term outcome in patients with basilar artery occlusion : a single center study / K. Fekete, J. Toth, H. Mate, M. Sandor, H. Toth, L. Csiba, I. Fekete
Dátum:2019
Megjegyzések:Background and Aims: Basilar artery occlusion (BAO) is a fatal disease despite recanalization techniques and limited data is available of the factors predicting outcome. Methods: Data of 100 patients treated with BAO was collected prospectively between 2004 and 2018. Risk factors, neurological status, outcome (case fatality, 3-months-mRS, one-year-survival); cranial CT (posterior circulation ASPECT score), result of CT angiography; and the treatment modality was given. Results: Average age was 64.9 13.7 years, 54% male. The most remarkable risk factor was previous stroke (29%), 55% of it vertebrobasilar (58% mortality). The onset to treatment time was 4.23 2.85 hours. The pc-ASPECT score was 10 in 67%, 7 points 33%. BAO was in the proximal part in 17%, in half in 20%, total in 21% and only the top in 42%; respectively within its group the mortality was 53%, 45%, 62%, 38%. Intravenous thrombolysis happened in 43%, intraarterial in 27%, combined therapy in 18% and 12% was treated conservatively. Case fatality within the treatment group was respectively: 48.8%, 55.5%, 33.3%, and 66.6% (p ? 0.8). Symptomatic haemorrhage was not different among the recanalization groups (p ? 0.83). Total or partial recanalization was achieved in 39%. There was a favourable trend in the recanalization rate of intraarterial and combined groups (p ? 0.4). At 3 months 23% had mRS 0?2, 3?5 42%, 58% were dead. At one year 26% was alive. Conclusions: The top occlusion of the BA, combined therapy may influence favourably the outcome. Among the risk factors previous VB stroke has a high impact. Trial registration number: N/A
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
haemorrhage
Megjelenés:European Stroke Journal. - 4 : Suppl. 1 (2019), p. 740. -
További szerzők:Tóth Judit (1964-) (radiológus) Máté H. Sándor Mária (1979-) (etnográfus) Tóth H. Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter)
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5.

001-es BibID:BIBFORM079830
Első szerző:Orbán-Kálmándi Rita Angéla (klinikai laboratóriumi kutató)
Cím:The use of ex vivo clot lysis assay for predicting outcomes in acute ischemic stroke patients who underwent intravenous thrombolysis / R. Kálmándi, I. Szegedi, I. Fekete, K. Fekete, F. Sarkady, L. Varga, L. Csiba, Z. Bagoly
Dátum:2019
Megjegyzések:Background and Aims: The outcome of intravenous thrombolysis using recombinant tissue plasminogen activator (rtPA) is favorable in only 33?35% of acute ischemic stroke (AIS) patients. We tested whether an ex vivo clot-lysis assay performed before thrombolysis might predict therapy outcomes. Methods: Blood samples of 139 consecutive AIS patients, who underwent intravenous thrombolysis, were taken before thrombolysis. Plateletpoor-plasma was clotted using recombinant tissue factor, then lysis was induced with rtPA. Clot formation and lysis was monitored by turbidimetry in real time. In order to test the impact of neutrophil extracellular traps on lysis, assays were also performed in the presence of cell-freeDNA and histone. Stroke severity was determined by NIHSS on admission. Short- and long-term outcomes were defined at 7 days and 3 months post-event according to the change in NIHSS and by the modified Rankin Scale, respectively. Results: The median time to reach 50% lysis (50%CLT) was 47.3 (IQR:35.0-64.0) min in the total cohort, and became significantly prolonged in the presence of DNA and histone. A dose-response relationship was observed between stroke severity and 50%CLT. Patients with favorable short-term outcome had significantly shorter 50%CLT in the presence of DNA and histone as compared to patients with worse outcomes (median:50.6 (IQR:36.8-70.5) min vs. 62.0 (IQR:45.0-74.7) min; p < 0.05). Long-term outcomes and occurrence of post-lysis hemorrhage showed no association with clot-lysis assay results. 742 European Stroke Journal 4(1S) Conclusions: Clot-lysis assay using plasma of AIS patients taken before thrombolysis might be useful to predict short-term outcomes, but showed no association with hemorrhagic complications and long-term outcomes.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
haemorrhage
Megjelenés:European Stroke Journal. - 4 : Suppl. 1 (2019), p. 742-743. -
További szerzők:Szegedi István (1992-) (orvos) Fekete István (1951-) (neurológus, pszichiáter) Fekete Klára (1978-) (neurológus) Sarkady Ferenc (1982-) (laboratóriumi analitikus) Varga L. Csiba László (1952-) (neurológus, pszichiáter) Bagoly Zsuzsa (1978-) (orvos)
Pályázati támogatás:GINOP-2.3.2-15-2016-00043
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6.

001-es BibID:BIBFORM090997
Első szerző:Paciaroni, Maurizio
Cím:Early recurrence in paroxysmal versus sustained atrial fibrillation in patients with acute ischaemic stroke / Maurizio Paciaroni, Filippo Angelini, Giancarlo Agnelli, Georgios Tsivgoulis, Karen L. Furie, Prasanna Tadi, Cecilia Becattini, Nicola Falocci, Marialuisa Zedde, Azmil H. Abdul-Rahim, Kennedy R. Lees, Andrea Alberti, Michele Venti, Monica Acciarresi, Riccardo Altavilla, Cataldo D'Amore, Maria G. Mosconi, Ludovica A. Cimini, Paolo Bovi, Monica Carletti, Alberto Rigatelli, Manuel Cappellari, Jukka Putaala, Liisa Tomppo, Turgut Tatlisumak, Fabio Bandini, Simona Marcheselli, Alessandro Pezzini, Loris Poli, Alessandro Padovani, Luca Masotti, Vieri Vannucchi, Sung-Il Sohn, Gianni Lorenzini, Rossana Tassi, Francesca Guideri, Maurizio Acampa, Giuseppe Martini, George Ntaios, Efstathia Karagkiozi, George Athanasakis, Kostantinos Makaritsis, Kostantinos Vadikolias, Chrysoula Liantinioti, Maria Chondrogianni, Nicola Mumoli, Domenico Consoli, Franco Galati, Simona Sacco, Antonio Carolei, Cindy Tiseo, Francesco Corea, Walter Ageno, Marta Bellesini, Giorgio Silvestrelli, Alfonso Ciccone, Umberto Scoditti, Licia Denti, Michelangelo Mancuso, Miriam Maccarrone, Giovanni Orlandi, Nicola Giannini, Gino Gialdini, Tiziana Tassinari, Maria Luisa De Lodovici, Giorgio Bono, Christina Rueckert, Antonio Baldi, Danilo Toni, Federica Letteri, Martina Giuntini, Enrico M. Lotti, Yuriy Flomin, Alessio Pieroni, Odysseas Kargiotis, Theodore Karapanayiotides, Serena Monaco, Mario M. Baronello, Laszló Csiba, Lilla Szabó, Alberto Chiti, Elisa Giorli, Massimo Del Sette, Davide Imberti, Dorjan Zabzuni, Boris Doronin, Vera Volodina, Patrik Michel Pd-Mer, Peter Vanacker, Kristian Barlinn, Lars-P. Pallesen, Jessica Kepplinger, Dirk Deleu, Gayane Melikyan, Faisal Ibrahim, Naveed Akhtar, Vanessa Gourbali, Shadi Yaghi, Valeria Caso
Dátum:2019
ISSN:2396-9873 2396-9881
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:European Stroke Journal. - 4 : 1 (2019), p. 55-64. -
További szerzők:Angelini, Filippo Agnelli, Giancarlo Tsivgoulis, Georgios Furie, Karen L. Tadi, Prasanna Becattini, Cecilia Falocci, Nicola Zedde, Marialuisa Abdul-Rahim, Azmil H. Lees, Kennedy R. Alberti, Andrea Venti, Michele Acciarresi, Monica Altavilla, Riccardo D'Amore, Cataldo Mosconi, Maria Giulia Cimini, Ludovica Anna Bovi, Paolo Carletti, Monica Rigatelli, Alberto Cappellari, Manuel Putaala, Jukka Tomppo, Liisa Tatlisumak, Turgut Bandini, Fabio Marcheselli, Simona Pezzini, Alessandro Poli, Loris Padovani, Alessandro Masotti, Luca Vannucchi, Vieri Sohn, Sung-Il Lorenzini, Gianni Tassi, Rossana Guideri, Francesca Acampa, Maurizio Martini, Giuseppe Ntaios, George Karagkiozi, Efstathia Athanasakis, George Makaritsis, Kostantinos Vadikolias, Kostantinos Liantinioti, Chrissoula Chondrogianni, Maria Mumoli, Nicola Consoli, Domenico Galati, Franco Sacco, Simona Carolei, Antonio Tiseo, Cindy Corea, Francesco Ageno, Walter Bellesini, Marta Silvestrelli, Giorgio Ciccone, Alfonso Scoditti, Umberto Denti, Licia Mancuso, Michelangelo Maccarrone, Miriam Orlandi, Giovanni Giannini, Nicola Gialdini, Gino Tassinari, Tiziana De Lodovici, Maria Luisa Bono, Giorgio Rueckert, Christina Baldi, Antonio Toni, Danilo Letteri, Federica Giuntini, Martina Lotti, Enrico Maria Flomin, Yuriy Pieroni, Alessio Kargiotis, Odysseas Karapanayiotides, Theodore Monaco, Serena Baronello, Mario Maimone Csiba László (1952-) (neurológus, pszichiáter) Szabó Lilla (1976-) (egyetemi tanár) Chiti, Alberto Giorli, Elisa Del Sette, Massimo Imberti, Davide Zabzuni, Dorjan Doronin, Boris Volodina, Vera Michel Pd-Mer, Patrik Vanacker, Peter Barlinn, Kristian Pallesen, Lars-Peder Kepplinger, Jessica Deleu, Dirk Melikyan, Gayane Ibrahim, Faisal Akhtar, Naveed Gourbali, Vanessa Yaghi, Shadi Caso, Valeria
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7.

001-es BibID:BIBFORM090999
Első szerző:Reinink, Hendrik
Cím:PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke. Rationale and design of a randomised, open, phase III, clinical trial with blinded outcome assessment / Hendrik Reinink, Jeroen C. de Jonge, Philip M. Bath, Diederik van de Beek, Eivind Berge, Saskia Borregaard, Alfonso Ciccone, Laszlo Csiba, Jacques Demotes, Diederik W. Dippel, Janika Kõrv, Iwona Kurkowska-Jastrzebska, Kennedy R. Lees, Malcolm R. Macleod, George Ntaios, Gary Randall, Götz Thomalla, H. Bart van der Worp
Dátum:2018
ISSN:2396-9873 2396-9881
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:European Stroke Journal. - 3 : 3 (2018), p. 291-298. -
További szerzők:de Jonge, Jeroen C. Bath, Philip M. van de Beek, Diederik Berge, Eivind Borregaard, Saskia Ciccone, Alfonso Csiba László (1952-) (neurológus, pszichiáter) Demotes-Mainard, Jacques Dippel, Diederik W. Körv, Janika Kurkowska-Jastrzebska, Iwona Lees, Kennedy R. Macleod, Malcolm R. Ntaios, George Randall, Gary Thomalla, Götz van der Worp, H. Bart
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8.

001-es BibID:BIBFORM079828
035-os BibID:(cikkazonosító)AS24-058
Első szerző:Szegedi István (orvos)
Cím:The association of plasminogen activator inhibitor-1 (pai-1) 4g/5g polymorphism with the risk and prognosis of intracerebral hemorrhage / I. Szegedi, T. Arokszallasi, I. Fekete, K. Fekete, A. Nagy, F. Sarkady, E. G. Székely, K. R. Czuriga-Kovacs, E. Berenyi, Z. Bagoly, L. Csiba
Dátum:2019
Megjegyzések:Background and Aims: Non-traumatic intracerebral hemorrhage accounts for 10?15% of all strokes, but has much higher mortality than acute ischemic stroke (AIS). Plasminogen activator inhibitor-1 (PAI-1) is a natural inhibitor of fibrinolysis that protects against bleeding. PAI-1 5G/ 5G genotype is associated with lower PAI-1 levels, thus we hypothesized that it could be associated with the risk and outcome of intracerebral hemorrhage. Methods: Three populations were included in the study: 51 patients with primary intracerebral haemorrhage (PICH), 13 patients with AIS who suffered hemorrhagic transformation after intravenous thrombolysis (AIS-ICH), and 118 AIS patients without hemorrhagic events (AIS). PAI-1 4G/5G polymorphism was determined in all patients. Clinical data was registered on admission and day 7 post-event. Short-term outcome was defined according to NIHSS change at 7 days. Long-term outcome was measured by the modified Rankin Scale at 3 months. Results: The presence of PAI-1 5G allele was significantly more frequent in the AIS-ICH group as compared to the AIS and PICH cohorts and a population control cohort. PAI-1 4G/5G polymorphism had no effect on stroke severity or short-term outcome in either groups. In a binary backward logistic regression model including age, gender, BMI, NIHSS on admission, hypertension, hyperlipidaemia it was revealed that PAI-1 5G/5G genotype confers an independent, significant risk for post-lysis intracranial hemorrhage (OR:4.75, 95%CI:1.18-19.06, p ? 0.028). PAI-1 4G/5G polymorphism had no influence on mortality and long-term outcome in the studied patient cohorts. Conclusions: PAI-1 5G/5G genotype confers an independent, significant risk for post-lysis intracerebral haemorrhage.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
haemorrhage
Megjelenés:European Stroke Journal. - 4 : Suppl. 1 (2019), p. 470. -
További szerzők:Árokszállási Tamás (1988-) (neurológus) Fekete István (1951-) (neurológus, pszichiáter) Fekete Klára (1978-) (neurológus) Nagy A. Sarkady Ferenc (1982-) (laboratóriumi analitikus) Székely Edina Gabriella Czuriga-Kovács Katalin Réka (1981-) (neurológus) Berényi Ervin (1964-) (radiológus) Bagoly Zsuzsa (1978-) (orvos) Csiba László (1952-) (neurológus, pszichiáter)
Pályázati támogatás:GINOP-2.3.2-15-2016-00043
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NKFI-K120042
NKFI
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9.

001-es BibID:BIBFORM079857
035-os BibID:(cikkazonosító)AS08-015
Első szerző:Tsivgoulis, Georgios
Cím:Intravenous thrombolysis for patients with in-hospital stroke onset : propensity-matched analysis from the SITS-EAST registry / G. Tsivgoulis, A. H. Katsanos, P. Kadlecova, A. Czlonkowska, A. Kobayashi, M. Brozman, V. Švigelj, L. Csiba, K. Fekete, J. Kõrv, V. Demarin, A. Vilionskis, D. Jatuzis, Y. Krespi, C. Liantinioti, S. Giannopoulos, R. Mikulik
Dátum:2017
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
stroke
Megjelenés:European Stroke Journal. - 2 : Suppl. 1 (2017), p. 71. -
További szerzők:Katsanos, Aristeidis H. Kadlecova, Pavla Czlonkowska, A. Kobayashi, Adam Brozman, Miroslav Švigelj, Victor Csiba László (1952-) (neurológus, pszichiáter) Fekete Klára (1978-) (neurológus) Kõrv, Janika Demarin V. Vilionskis, Aleksandras Jatuzis, Dalius Krespi, Yakup Liantinioti, Chrissoula Giannopoulos, Sotirios Mikulík, Robert
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