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001-es BibID:BIBFORM029276
Első szerző:Magyar Mária Tünde (neurológus)
Cím:Carotid artery auscultation - anachronism or useful screening procedure? / Magyar, M. T., Nam, E. M., Csiba, L., Ritter, M. A., Ringelstein, E. B., Droste, D. W.
Dátum:2002
ISSN:0161-6412
Megjegyzések:Carotid bruits are supposed to indicate the presence of high-grade common carotid or extracranial internal carotid artery stenosis in a large proportion of patients. Using a stethoscope, we prospectively auscultated 273 carotid arteries of 145 patients blinded to the results of a complete extracranial and intracranial Doppler investigation including extracranial color-coded duplex ultrasound. Fifty-four arteries showed stenosis of > or = 50%-99%, or occlusion of the extracranial internal or the common carotid artery. In 25 of these arteries, a bruit was present. In 9 out of 16 patients with extracranial stenosis from 70%-99%, a bruit was detected. In one additional patient with a middle-grade external carotid artery stenosis, a bruit was also present. In seven additional patients, a bruit was present in the absence of any carotid artery stenosis, cardiac vitium or goiter. The sensitivity of carotid auscultation for the detection of a 70%-99% stenosis of the common or extracranial internal carotid artery was 56% and specificity was 91%. The positive predictive value of a bruit found during carotid auscultation was 27%, and the negative predictive value of a normal auscultation was 97%. Carotid auscultation is a useful screening procedure in the detection of carotid stenosis or occlusion, but requires confirmation by carotid ultrasound.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Neurological Research. - 24 : 7 (2002), p. 705-708. -
További szerzők:Nam, E. M. Csiba László (1952-) (neurológus, pszichiáter) Ritter, Martin A. Ringelstein, E. Bernd Droste, Dirk W.
Internet cím:DOI
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2.

001-es BibID:BIBFORM037836
Első szerző:Zsuga Judit (neurológus, pszichoterapeuta, egészségügyi szakmanager)
Cím:Different effect of hyperglycemia on stroke outcome in non-diabetic and diabetic patients : a cohort study / Zsuga Judit, Gesztelyi Rudolf, Kemeny-Beke Adam, Fekete Klara, Mihalka Laszlo, Szabo Adrienn, Kardos Laszlo, Csiba Laszlo, Bereczki Daniel
Dátum:2012
ISSN:0161-6412
Megjegyzések:OBJECTIVES: Relationship between hyperglycemia and stroke outcome is unclear, partly due to the small sample size in most studies, and partly due to lack of consensus concerning the cutoff level for hyperglycemia. METHODS: In a cohort study, we investigated whether on-admission hyperglycemia is an independent predictor for 30-day case fatality by analyzing data of 2496 consecutive computed tomography (CT) verified acute ischemic stroke patients (2077 non-diabetic and 419 diabetic) included in the prospective, hospital-based Debrecen Stroke Database. Instead of using an arbitrary cutoff level for hyperglycemia, quartiles of on-admission glucose level were used for Kaplan-Meier survival curves and Cox proportional hazard modeling. RESULTS: The four quartiles of serum glucose level were in the range as follows: <5.2 mmol/l, 5.201-6.1 mmol/l, 6.101-7.5 mmol/l, and >7.501 mmol/l (n = 664, 618, 597, and 617, respectively). Among all 2496 participants, the adjusted hazard ratios for death increased with each quartile of admission glucose 1.96 [95% confidence interval (CI): 1.07-3.60; P = 0.03], 1.56 (95% CI: 0.83-2.94; P = 0.17), and 3.04 (95% CI: 1.70-5.44; P < 0.0001) for the second, third, and fourth quartiles, respectively). Upon stratification with respect to diabetes, we found similarly high risk for poor outcome among non-diabetic patients, while the risk was considerably lower among diabetic patients. DISCUSSION: These data suggest that even mild elevation of on-admission glucose levels is an independent predictor of 30-day case fatality. So, we propose that the ideal target blood glucose level is lower for non-diabetic than diabetic patients.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Stroke
Ischemic stroke
Diabetes mellitus
Hyperglycemia
Survival
Megjelenés:Neurological Research. - 34 : 1 (2012), p. 72-79. -
További szerzők:Gesztelyi Rudolf (1969-) (kísérletes farmakológus) Kemény-Beke Ádám (1968-2021) (szemész) Fekete Klára (1978-) (neurológus) Mihálka László (1950-) (neurológus) Szabó Adrienn Mónika (1982-) (orvos) Kardos László (1970-) (megelőző orvostan és népegészségtan szakorvos) Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
Pályázati támogatás:ETT 158/2009
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