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001-es BibID:	BIBFORM029324
Első szerző:	Ritter, Martin A.
Cím:	Role of cerebral amyloid angiopathy in intracerebral hemorrhage in hypertensive patients / Ritter, M. A., Droste, D. W., Hegedus, K., Szepesi, R., Nabavi, D. G., Csiba, L., Ringelstein, E. B.
Dátum:	2005
ISSN:	0028-3878
Megjegyzések:	To assess the interaction of cerebral amyloid angiopathy (CAA) and arterial hypertension as cofactors for intracerebral hemorrhage (ICH). METHODS: The authors investigated 129 postmortem brains of hypertensive patients with and without ICH. Sixty-four patients had had deep (n = 40) or lobar (n = 24) ICH. Sixty-five patients without ICH served as controls. Established risk factors for ICH (age, gender, severity of hypertension, bleeding disorders, intake of anticoagulants, and chronic alcoholism) were identified from medical records. Four specimens per brain were stained with hematoxylin-eosin and Congo red. The entire ICH cohort and subgroups were compared with controls using single-factor and multiple logistic regression analyses. RESULTS: CAA was found in 15 of 64 subjects (23%) with ICH and in five of 65 controls (8%; p = 0.026). In single-factor analysis, CAA was more prevalent in lobar ICH compared with controls (p = 0.007) but not in deep ICH. Poor control of hypertension was more prevalent in the entire ICH group (p = 0.01) and in deep ICH (p = 0.016) but not in lobar ICH. ICH was predictive of the presence of CAA (odds ratio: 5.6, 95% CI: 1.8 to 19.5, p = 0.003), and CAA was more likely to be found in lobar ICH in multivariable-adjusted analysis. After adjustment for conventional risk factors, there was a weak association between CAA and deep ICH. CONCLUSION: Cerebral amyloid angiopathy plays a major role in the pathogenesis of intracerebral hemorrhage even in patients with more evident risk factors.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Neurology. - 64 : 7 (2005), p. 1233-1237. -
További szerzők:	Droste, Dirk W. Hegedűs Katalin (1946-2017) (ideggyógyász, neuropathológus) Szepesi Rita (1975-) (neurológus) Nabavi, D. G. Csiba László (1952-) (neurológus, pszichiáter) Ringelstein, E. Bernd
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001-es BibID:	BIBFORM039193
Első szerző:	Schulte-Altedorneburg, Gernot
Cím:	Visualization of the basilar artery by transcranial color-coded duplex sonography : comparison with postmortem results / Schulte Altedorneburg, G., Droste, D. W., Popa, V., Wohlgemuth, W. A., Kellermann, M., Nabavi, D. G., Csiba, L., Ringelstein, B.
Dátum:	2000
ISSN:	0039-2499
Megjegyzések:	Transcranial color-coded sonography (TCCS) via the suboccipital approach allows direct and continuous visualization of the basilar artery (BA). In this study, we intended to evaluate the ability of native TCCS in visualizing the length of the BA by means of a comparison with postmortem measurements. METHODS: The BA was prospectively studied by TCCS shortly before death (median 3 days) in 46 moribund neurological patients (mean+/-SD age 71.1+/-13.1 years). The length of the BA was determined by measuring the distance between the vertebrobasilar junction and the deepest available flow signal in the top of the BA. During autopsy, photos of the vertebrobasilar system were taken to evaluate the true anatomic length and variations of the course of BA in situ, eg, straight, curved, or S-shaped. RESULTS: Comparison of the in vivo ultrasound measurements of BA length and postmortem data was possible in 44 of 46 cases. In the 2 remaining patients, the BA was occluded. The mean insonation depth of the vertebrobasilar junction was found at 66.9+/-7.1 mm. The mean BA length was 21.5+/-6. 8 mm by color-coded duplex and 32.9+/-6 mm anatomically (P<0.0001). The mean difference between color mode and anatomic findings was 11. 3+/-6.4 mm in the case of a straight BA (35 cases) and 16.3+/-4.8 mm in an anatomically tortuous course of the BA (9 cases). CONCLUSIONS: Color duplex imaging enables correct visualization of the proximal two thirds of the BA, but only exceptionally of its distal one third. A tortuous course of the BA leads to an underestimation of its anatomic length.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Stroke. - 31 : 5 (2000), p. 1123-1127. -
További szerzők:	Droste, Dirk W. Popa, Vasile Wohlgemuth, W. A. Kellermann Mónika (1971-) (pszichiáter) Nabavi, D. G. Csiba László (1952-) (neurológus, pszichiáter) Ringelstein, E. Bernd
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat DOI
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