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1.

001-es BibID:BIBFORM029951
Első szerző:Bereczki Dániel (neurológus)
Cím:Mannitol use in acute stroke : case fatality at 30 days and 1 year / Bereczki D., Mihálka L., Szatmári S., Fekete K., Di Cesar D., Fülesdi B., Csiba L., Fekete I.
Dátum:2003
ISSN:0039-2499
Megjegyzések:BACKGROUND AND PURPOSE: Mannitol is used worldwide to treat acute stroke, although its efficacy and safety have not been proven by randomized trials.METHODS:In a tricenter, prospective study, we analyzed the 30-day and 1-year case fatality with respect to mannitol treatment status in 805 patients consecutively admitted within 72 hours of stroke onset. Confounding factors were compared between treated and nontreated patients.RESULTS:Two thirds of the patients received intravenous mannitol as part of their routine treatment (mean dose, 47+/-22 g/d; mean duration, 6+/-3 days). The case fatality was 25% versus 16% (P=0.006) at 30 days and 38% versus 25% (P<0.001) at 1 year in the-mannitol treated and nontreated groups, respectively. Mannitol treatment effect was adjusted for age, stroke severity, fever in the first 3 days, and aspirin treatment (for ischemic strokes) in logistic regression models. Depending on the factors entered into the model, either no effect or harm could be attributed to mannitol. When the analysis was restricted to those admitted within 24 hours (n=568), case fatality differed significantly only at 1 year (35% in treated and 26% in nontreated patients, P=0.044). Although the prognostic scores of the Scandinavian Neurological Stroke Scale were similar in treated and nontreated patients, both in ischemic and hemorrhagic strokes, the patient groups differed in several factors that might also have influenced survival.CONCLUSIONS:Based on the results of this study, no recommendations can be made on the use of mannitol in acute stroke, and properly randomized, controlled trials should be performed to come to a final conclusion.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Stroke. - 34 : 7 (2003), p. 1730-1735. -
További szerzők:Mihálka László (1950-) (neurológus) Szatmári Szabolcs (1960-) (neurológus) Fekete Klára (1978-) (neurológus) Di Cesar, D. Fülesdi Béla (1961-) (aneszteziológus) Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter)
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2.

001-es BibID:BIBFORM079826
Első szerző:Fekete Klára (neurológus)
Cím:Alcohol consumption and smoking are associated with higher 30-day case fatality after stroke in the mures-uzhgorod-debrecen (mud) database / K. E. Fekete, S. Szatmári, I. Szőcs, C. Szekeres, J. Szász, L. Mihálka, V. Smolanka, L. Csiba, D. Bereczki
Dátum:2008
ISSN:1015-9770
Megjegyzések:Abstract Introduction: Age, alcohol consumption, smoking are important risk factors of stroke. After stroke most of the patients suffer from different grade of disability. Methods: In this work the risk factors, mentioned above, the disability and the 30 day case fatality was investigated by analyzing the data of 1047 patients from the MUD database between the 1 st of October 1999 and 30th of September 2000. (The distribution of the patients in the database is the following: 554 patients in Debrecen, 260 patients in Targu Mures and 233 in Uzhgorod). Results: The distribution of stroke concerning the genders by our database is the following: 42,5% female, 57,5 % male. Before discharge 222 patients (22,1%) died. By 172 of the patients (16,4%) occurred stroke in the familial-history. The ratio of the age was found more unfavorable by males: between 30 and 60 years the frequency of stroke was twice as high as by females (on the average by 30,75% of women and 69,26% of men suffer stroke).The ratio is very similar by cerebral bleeding not only ischemia. 249 of total stroke patients admitted alcohol consumption (23,8%), 551 did not (52,6%) (28,6%is unknown). The 30 day mortality rate was 25,3% between the patients admitting alcohol consumption, and only 9,3% between those who did not. In total 339 patients suffered cerebral bleeding ( 32,4%), which is higher then the literary dates. No difference was found between the 3 examination places. The ratio of death in the group of alcohol consumers and alcohol-non-consumer was equally prominently high without any difference. In our database 25,09% of the patients smoked. The excess of disability at dismission was analyzed by 825 patients with the following results: 153 patients (18,5%) needed permanent care, 182 (22%) patients needed help by every-day-life, 230 (27,5%) patients could live a self-sufficient life with residual signs, and 260 (31,5%) had no neurological sign. Results and conclusion: The analysis of the MUD database emphasizes the medical education of the population in health policy.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idézhető absztrakt
stroke
Megjelenés:Cerebrovascular Diseases. - 25 : 2 (2008), p. 71. -
További szerzők:Szatmári Szabolcs (1960-) (neurológus) Szőcs Ildikó (1970-) (orvos) Szekeres Csilla Cecília (1980-) (orvos) Szász József (1960-) (neurológus) Mihálka László (1950-) (neurológus) Smolanka, Volodymyr I. (1950-) (orvos) Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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3.

001-es BibID:BIBFORM049525
Első szerző:Fekete Klára (neurológus)
Cím:Prestroke Alcohol Consumption and Smoking Are Not Associated with Stroke Severity, Disability at Discharge, and Case Fatality / Klára Fekete, Szabolcs Szatmári, Ildikó Szőcs, Csilla Szekeres, József Szász, László Mihálka, Volodymyr Smolanka, László Kardos, László Csiba, Dániel Bereczki
Dátum:2014
Megjegyzések:Background: Heavy alcohol consumption and smoking are known risk factors for stroke but their influence on stroke severity and outcome may also be important. We tested if alcohol consumption and smoking relate to initial stroke severity, disability at discharge from hospital and outcome at 30 days and at 1 year in 1049 patients of the Mures-Uzhgorod-Debrecen database. Methods: Initial stroke severity was scored by the NIH stroke scale. Case fatality and the modified outcome scale of the 1st International Stroke Trial were used to assess outcome. We used multiple regression analysis.Results: Before their stroke, 24.5% were smokers and 24.7 % admitted regular alcohol consumption. Neither smoking nor alcohol consumption status were associated with initial stroke severity. Case fatality at discharge, at 30 days and at 1 year were 12.2%, 16.9% and 28.3%, respectively. Initial stroke severity, hemorrhagic subtype, and age in men over 60 years were strong predictors of outcome. We did not find significant difference among alcohol consumers and non-consumers in 30-day and in one year case fatality in all stroke patients and in ischemic stroke patients. In hemorrhagic stroke, there was a non-significant tendency for higher case fatality among alcohol-consumers (39.5% vs. 26.4%, p>0.2 at 30 days and 48.8% vs. 35.8%, p>0.2 at 1 year). Smoking did not influence significantly the outcome at 30-days and at one-year.Conclusion: despite being risk factors, pre-stroke smoking and alcohol consumption do not have a significant influence on stroke severity and on short- and long- term outcome.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Alcohol, smoking and stroke severity
Megjelenés:Journal of Stroke and Cerebrovascular Diseases. - 23 : 1 (2014), p. e31-e37. -
További szerzők:Szatmári Szabolcs (1960-) (neurológus) Szőcs Ildikó (1970-) (orvos) Szekeres Csilla Cecília (1980-) (orvos) Szász József (1960-) (neurológus) Mihálka László (1950-) (neurológus) Smolanka, Volodymyr I. (1950-) (orvos) Kardos László (1970-) (megelőző orvostan és népegészségtan szakorvos) Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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4.

001-es BibID:BIBFORM040229
Első szerző:Kerényi Levente
Cím:Factors influencing hemorrhagic transformation in ischemic stroke : a clinicopathological comparison / Kerényi, L., Kardos, L., Szász, J., Szatmári, Sz., Bereczki, D., Hegedüs, K., Csiba, L.
Dátum:2006
ISSN:1351-5101
Megjegyzések:As hemorrhagic transformation (HTr) is a frequent complication and can worsen the outcome of acute ischemic stroke, our aim was to assess the risk factors of HTr. Using the database of our neuropathological laboratory, 245 consecutive acute ischemic stroke patients were analyzed. An exploratory logistic regression procedure was carried out to find the best multiple model identifying the factors associated with HTr. The autopsy revealed ischemic infarct in 175 (71%) and ischemic infarct with HTr in 70 (29%) patients. Mean age was 71.5 +/- 11.4 years (mean +/- SD) and 74.8 +/- 10.2 years (mean +/- SD), respectively. The multiple model confirmed age in case of embolic stroke, and diabetes mellitus and infarct size as independent risk factors of HTr. It seems that not serum glucose level but diabetes mellitus in the case history is an independent predictor of HTr.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:European Journal Of Neurology 13 : 11 (2006), p. 1251-1255. -
További szerzők:Kardos László (1970-) (megelőző orvostan és népegészségtan szakorvos) Szász József (1960-) (neurológus) Szatmári Szabolcs (1960-) (neurológus) Bereczki Dániel (1960-) (neurológus) Hegedűs Katalin (1946-2017) (ideggyógyász, neuropathológus) Csiba László (1952-) (neurológus, pszichiáter)
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5.

001-es BibID:BIBFORM062621
035-os BibID:(WoS)000369198600006 (Scopus)84960155748
Első szerző:Orbán-Kis Károly
Cím:Comparison of hospitalized acute stroke patients' characteristics using two large central-eastern european databases / Károly Orbán-Kis, Ildikó Szőcs, Klára Fekete, László Mihálka, László Csiba, Dániel Bereczki, Szabolcs Szatmári
Dátum:2016
ISSN:0019-1442
Megjegyzések:Objectives: Stroke is the third leading cause of death inthe European region. In spite of a decreasing trend, strokerelated mortality remains higher in Hungary and Romaniawhen compared to the EU average. This might be due tohigher incidence, increased severity or even less effectivecare.Methods: In this study we used two large, hospital baseddatabases from Targu Mures (Romania) and Debrecen(Hungary) to compare not only the demographic characteristicsof stroke patients from these countries but also the riskfactors, as well as stroke severity and short term outcome.Results: The gender related distribution of patients wassimilar to those found in the European Survey, whereas themean age of patients at stroke onset was similar in the twocountries but lower by four years. Although the length ofhospital stay was significantly different in the two countries itwas still much shorter (about half) than in most reports fromwestern European countries. The overall fatality rate in bothdatabases, regardless of gender was comparable to averagesfrom Europe and other countries. In both countries wefound a high number of risk factors, frequently overlapping.The prevalence of risk factors (hypertension, smoking,hyperlipidaemia) was higher than those reported in othercountries, which can explain the high ratio of recurringstroke.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény hazai lapban
folyóiratcikk
Megjelenés:Ideggyógyászati Szemle. - 69 : 1-2 (2016), p. 47-53. -
További szerzők:Szőcs Ildikó (1970-) (orvos) Fekete Klára (1978-) (neurológus) Mihálka László (1950-) (neurológus) Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus) Szatmári Szabolcs (1960-) (neurológus)
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6.

001-es BibID:BIBFORM029923
Első szerző:Szász József (neurológus)
Cím:Agyérkatasztrófák következtében elhunyt betegek agy- és szív-érrendszeri boncleletének összehasonlítása / Szász J., Szatmári S., Csiba L., Hegedüs K., Bereczki D., Fekete I.
Dátum:1998
Tárgyszavak:Orvostudományok Klinikai orvostudományok magyar nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Orvostudományi Értesítő 77 (1998), p. 44-45. -
További szerzők:Szatmári Szabolcs (1960-) (neurológus) Csiba László (1952-) (neurológus, pszichiáter) Hegedűs Katalin (1946-2017) (ideggyógyász, neuropathológus) Bereczki Dániel (1960-) (neurológus) Fekete István (1951-) (neurológus, pszichiáter)
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7.

001-es BibID:BIBFORM029947
Első szerző:Szatmári Szabolcs (neurológus)
Cím:The Mures-Uzhgorod-Debrecen study : a comparison of hospital stroke services in Central-Eastern Europe / Szatmari, S., Pascu, I., Mihalka, L., Mulesa, S. V., Fekete, I., Fulesdi, B., Csiba, L., Zselyuk, G., Szasz, J., Gebefugi, J., Nicolescu, S., Vasiesiu, D., Smolanka, V. I., Bereczki, D.
Dátum:2002
ISSN:1351-5101
Megjegyzések:Stroke mortality is extremely high in Central-Eastern European countries. The high rate of risk factors and differences in health care services might be among the factors resulting in high stroke morbidity and mortality in this region. As only few prospectively collected information are available from this region, we decided to evaluate some characteristics of stroke services in neurological departments of a Romanian, a Ukrainian and a Hungarian city in the framework of the Mure₀s-Uzhgorod-Debrecen comparative epidemiological study. We registered demographic data, the absence or presence of the most important risk factors, and clinical signs on admission and at discharge. We recorded the application of various diagnostic methods, stroke treatment and recommendations for secondary prevention. Follow-up is planned after 30 days and after 1 year. The paper summarizes the methodology of this prospective epidemiological study of stroke patients hospitalized in neurological departments in T©argu Mure₀s, Uzhgorod and Debrecen, three Central-Eastern European cities in Romania, Ukraine and Hungary, respectively.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:European Journal Of Neurology. - 9 : 3 (2002), p. 293-296. -
További szerzők:Pascu, I. Mihálka László (1950-) (neurológus) Mulesa, S. V. Fekete István (1951-) (neurológus, pszichiáter) Fülesdi Béla (1961-) (aneszteziológus) Csiba László (1952-) (neurológus, pszichiáter) Zselyuk, G. Szász József (1960-) (neurológus) Gebefügi, J. Nicolescu, S. Vasiesiu, D. Smolanka, Volodymyr I. (1950-) (orvos) Bereczki Dániel (1960-) (neurológus)
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8.

001-es BibID:BIBFORM029946
Első szerző:Szatmári Szabolcs (neurológus)
Cím:Subcortical features and cognitive performance in Hungarian cerebrovascular outpatients / Szatmári Szabolcs, Csiba László, Fekete István, Bereczki Dániel
Dátum:2002
ISSN:0022-510X
Megjegyzések:Cerebrovascular diseases are common in Central and East Europe, and the resulting cognitive impairment is probably also frequent. Although this problem attracted a lot of attention in the last decade, systematic examination of cognitive functions is not routinely performed in cerebrovascular patients. In our study involving cerebrovascular outpatients, we used the MMSE and the Barthel Index combined with a checklist for the evaluation of subcortical features. From a total of 176 cases, 32% had at least one subcortical sign. Except for gait disturbance and unprovoked falls, patients with subcortical dysfunction had lower performances on MMSE and lower Barthel scores. Their mean age did not differ significantly from the age of patients without subcortical signs, except for the subgroups with urinary and gait disturbances. Cognitive deficit could be detected in 27 patients, nine of them fulfilled the criteria for dementia. Subcortical signs and cognitive impairment can also be present in apparently well-being cerebrovascular patients. The routine evaluation of these deficiencies must be an integral part of the management of cerebrovascular patients and in planning their complex rehabilitation. Short, widely usable and easily executable tests are recommended.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Journal Of The Neurological Sciences. - 203-204 (2002), p. 99-101. -
További szerzők:Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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9.

001-es BibID:BIBFORM029930
Első szerző:Szatmári Szabolcs (neurológus)
Cím:Screening of vascular cognitive impairment on a Hungarian cohort / Szatmari, S., Fekete, I., Csiba, L., Kollar, J., Sikula, J., Bereczki, D.
Dátum:1999
ISSN:1323-1316
Megjegyzések:Cerebrovascular disease is a major public health problem in Eastern European countries. A Hungarian post-stroke population was examined to estimate the rate of dementia, the risk factors for cognitive impairment, and the applicability of a recently established Canadian diagnostic checklist in this cohort. Chronic cerebrovascular outpatients were screened for cognitive impairment with a combined checklist: the Diagnostic Checklist for Vascular Dementia established by the Consortium of Canadian Centres for Clinical Cognitive Research using the Mini Mental State Examination instead of the detailed neuropsychological part of the Checklist. Of the 247 consecutive patients at a cerebrovascular outpatient unit, 176 had cerebrovascular disorder diagnosed either by computed tomography (CT; n=126) or by the clinical signs. Of these, 15% were cognitively impaired and 5% fulfilled the criteria of dementia. The mean age of the patients with cognitive impairment was significantly higher than that of patients with normal cognition (68.2+/-10.2 and 60.5+/-10.5 years, P<0.001). The Barthel index was significantly lower in the cognitively affected group than in non-affected patients (92.4+/-16.0 and 97.1+/-8.7, P=0.027). Diabetes and more than two subcortical infarcts on CT or magnetic resonance imaging were more frequent in patients with cognitive loss (P=0.043 and P=0.013, respectively). Cognitive performance was also influenced by the level of education. Higher age, diabetes, motor deficits, and multiple subcortical infarcts are risk factors for cognitive impairment after stroke. The combined checklist appears to be a practical screening test for cognitive impairment in patients with chronic cerebrovascular diseases.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Psychiatry And Clinical Neurosciences. - 53 : 1 (1999), p. 39-43. -
További szerzők:Fekete István (1951-) (neurológus, pszichiáter) Csiba László (1952-) (neurológus, pszichiáter) Kollár József (1950-) (radiológus) Sikula Judit (1954-) (radiológus) Bereczki Dániel (1960-) (neurológus)
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10.

001-es BibID:BIBFORM029924
Első szerző:Szatmári Szabolcs (neurológus)
Cím:Krónikus agyérbetegek szellemi teljesítményei : prospektív vizsgálat járóbeteg rendelésen / Szatmári S., Szász J., Bereczki D., Fekete I., Csiba L.
Dátum:1998
Tárgyszavak:Orvostudományok Klinikai orvostudományok magyar nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Orvostudományi Értesítő 77 (1998), p. 46-47. -
További szerzők:Szász József (1960-) (neurológus) Bereczki Dániel (1960-) (neurológus) Fekete István (1951-) (neurológus, pszichiáter) Csiba László (1952-) (neurológus, pszichiáter)
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