CCL

Összesen 2 találat.
#/oldal:
Részletezés:
Rendezés:

1.

001-es BibID:BIBFORM065094
Első szerző:Viski Sándor Zsolt (orvos)
Cím:The acute effects of alcohol on cerebral hemodynamic changes induced by the head-up tilt test in healthy subjects / Sandor Viski, Miklos Orosz, Katalin Reka Czuriga-Kovacs, Maria Tunde Magyar, Laszlo Csiba, Laszlo Olah
Dátum:2016
ISSN:0022-510X
Megjegyzések:Background: Alcohol is a known triggering factor for orthostatic dysfunction, increasing the risk of neurally-mediated syncope. Since orthostatic tolerance may be affected by both systemic and cerebral hemodynamic changes, our aim was to investigate the acute effects of alcohol on cerebral vasoreactivity measured during the head-up tilt (HUT) test in 20 healthy subjects.Methods: Mean arterial blood pressure (mBP), heart rate, and flow parameters in both middle cerebral arteries (MCAs) were continuously recorded in the supine and during a 10-minute HUT positions before and after alcohol intake.Results: The HUT test resulted in a more prominent decline of adjusted mBP at the level of MCAs (mBPMCA) and a significantly larger decrease of MCA mean flow velocities (MFVMCA) in the post-alcohol period than before alcohol intake. During the HUT phase, the relative decrease in MFVMCA was significantly smaller than the reduction in mBPMCA before drinking alcohol, while these changes were similar after alcohol ingestion. The cerebrovascular resistance index (CVRi) decreased during the HUT phase in the control period, however, it increased after alcohol intake.Conclusion: The similar decrease inmBPMCA and MFVMCA during orthostatic stress after alcohol ingestion together with the increased CVRi indicated the impairment of the compensatory vasodilation of cerebral resistance vessels, i.e. impaired cerebral autoregulation. These findings suggest that alcohol may contribute to impaired orthostatic tolerance not only by a hypotensive response but also by the alteration of cerebral blood flow regulation.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Alcohol
Orthostatic stress
Head-up tilt test
Cerebral blood flow
Cerebral autoregulation
Baroreceptor reflex
Transcranial doppler
Megjelenés:Journal Of The Neurological Sciences 368 (2016), p. 113-120. -
További szerzők:Orosz Miklós Czuriga-Kovács Katalin Réka (1981-) (neurológus) Magyar Mária Tünde (1970-) (neurológus) Csiba László (1952-) (neurológus, pszichiáter) Oláh László (1967-) (neurológus)
Pályázati támogatás:NAP_13-1-2013-0001
Egyéb
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:

2.

001-es BibID:BIBFORM063682
Első szerző:Viski Sándor Zsolt (orvos)
Cím:Effect of reading on blood flow changes in the posterior cerebral artery in early blind and sighted people : a transcranial Doppler study / Sandor Viski, David Orgovan, Katalin Szabo, Bernhard Rosengarten, Laszlo Csiba, Laszlo Olah
Dátum:2016
ISSN:0022-510X
Megjegyzések:BackgroundNeuroimaging studies proved that Braille reading resulted in visual cortex activation in blind people, however, very few data are available about the measure of flow increase in these subjects. Therefore, we investigated the flow response in the posterior cerebral artery (PCA) of eleven early blind and ten sighted subjects induced by reading Braille and print, respectively.MethodsTwo experimental protocols were used in both groups: PCA flow velocity during reading was compared to the resting phase and "NLC" phase (volunteers "read" non-lexical characters; e.g. .,-.:,-.:...,). The use of these experimental protocols allowed to investigate separately the effect of "light stimulus + print reading" versus "print reading alone" in sighted, and "hand/finger movement + Braille reading" versus "Braille reading alone" in blind subjects.ResultsThe flow response in the PCA evoked by "Braille reading alone" in blind (10.5 ? 4.5%) and "print reading alone" in sighted subjects (8.1 ? 3.5%) was similar. The flow increase induced by "hand/finger movement + Braille reading" and by "Braille reading alone" did not differ in blind people, however, "light stimulus + print reading" in sighted subjects caused higher PCA flow increase (25.9 ? 6.9%) than "print reading alone" (8.1 ? 3.5%).ConclusionThe similar PCA flow response induced by Braille and print reading alone suggested a similar degree of occipital cortex activation in blind and sighted subjects. In sighted people, the 3-times higher flow velocity increase induced by "light stimulus + print reading" compared with "print reading alone" indicated that 2/3 of PCA flow increase during reading was due to the light stimulus and only 1/3 of flow response was caused by reading alone.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Cortical activation
Blind subjects
Cerebral blood flow
Neurovascular coupling
Transcranial Doppler
Megjelenés:Journal Of The Neurological Sciences 363 (2016), p. 132-139. -
További szerzők:Orgovan, David Szabó Katalin Judit (1984-) (neurológus) Rosengarten, Bernhard Csiba László (1952-) (neurológus, pszichiáter) Oláh László (1967-) (neurológus)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Rekordok letöltése1