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1.

001-es BibID:BIBFORM090994
Első szerző:Altavilla, Riccardo
Cím:Anticoagulation After Stroke in Patients With Atrial Fibrillation : to Bridge or Not With Low-Molecular-Weight Heparin? / Altavilla Riccardo, Caso Valeria, Bandini Fabio, Agnelli Giancarlo, Tsivgoulis Georgios, Yaghi Shadi, Furie Karen L., Tadi Prasanna, Becattini Cecilia, Zedde Marialuisa, Abdul-Rahim Azmil H., Lees Kennedy R., Alberti Andrea, Venti Michele, Acciarresi Monica, D'Amore Cataldo, Mosconi Maria Giulia, Cimini Ludovica Anna, Fusaro Jessica, Bovi Paolo, Carletti Monica, Rigatelli Alberto, Cappellari Manuel, Putaala Jukka, Tomppo Liisa, Tatlisumak Turgut, Marcheselli Simona, Pezzini Alessandro, Poli Loris, Padovani Alessandro, Masotti Luca, Vannucchi Vieri, Sohn Sung-Il, Lorenzini Gianni, Tassi Rossana, Guideri Francesca, Acampa Maurizio, Martini Giuseppe, Ntaios George, Athanasakis George, Makaritsis Konstantinos, Karagkiozi Efstathia, Vadikolias Konstantinos, Liantinioti Chrysoula, Chondrogianni Maria, Mumoli Nicola, Consoli Domenico, Galati Franco, Sacco Simona, Carolei Antonio, Tiseo Cindy, Corea Francesco, Ageno Walter, Bellesini Marta, Silvestrelli Giorgio, Ciccone Alfonso, Lanari Alessia, Scoditti Umberto, Denti Licia, Mancuso Michelangelo, Maccarrone Miriam, Ulivi Leonardo, Orlandi Giovanni, Giannini Nicola, Gialdini Gino, Tassinari Tiziana, De Lodovici Maria Luisa, Bono Giorgio, Rueckert Christina, Baldi Antonio, D'Anna Sebastiano, Toni Danilo, Letteri Federica, Giuntini Martina, Lotti Enrico Maria, Flomin Yuriy, Pieroni Alessio, Kargiotis Odysseas, Karapanayiotides Theodore, Monaco Serena, Baronello Mario Maimone, Csiba Laszló, Szabó Lilla, Chiti Alberto, Giorli Elisa, Del Sette Massimo, Imberti Davide, Zabzuni Dorjan, Doronin Boris, Volodina Vera, Michel Patrik, Vanacker Peter, Barlinn Kristian, Pallesen Lars-Peder, Barlinn Jessica, Deleu Dirk, Melikyan Gayane, Ibrahim Faisal, Akhtar Naveed, Gourbali Vanessa, Paciaroni Maurizio
Dátum:2019
ISSN:0039-2499
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Stroke. - 50 : 8 (2019), p. 2093-2100. -
További szerzők:Caso, Valeria Bandini, Fabio Agnelli, Giancarlo Tsivgoulis, Georgios Yaghi, Shadi Furie, Karen L. Tadi, Prasanna Becattini, Cecilia Zedde, Marialuisa Abdul-Rahim, Azmil H. Lees, Kennedy R. Alberti, Andrea Venti, Michele Acciarresi, Monica D'Amore, Cataldo Mosconi, Maria Giulia Cimini, Ludovica Anna Fusaro, Jessica Bovi, Paolo Carletti, Monica Rigatelli, Alberto Cappellari, Manuel Putaala, Jukka Tomppo, Liisa Tatlisumak, Turgut Marcheselli, Simona Pezzini, Alessandro Poli, Loris Padovani, Alessandro Masotti, Luca Vannucchi, Vieri Sohn, Sung-Il Lorenzini, Gianni Tassi, Rossana Guideri, Francesca Acampa, Maurizio Martini, Giuseppe Ntaios, George Athanasakis, George Makaritsis, Kostantinos Karagkiozi, Efstathia Vadikolias, Kostantinos Liantinioti, Chrissoula Chondrogianni, Maria Mumoli, Nicola Consoli, Domenico Galati, Franco Sacco, Simona Carolei, Antonio Tiseo, Cindy Corea, Francesco Ageno, Walter Bellesini, Marta Silvestrelli, Giorgio Ciccone, Alfonso Lanari, Alessia Scoditti, Umberto Denti, Licia Mancuso, Michelangelo Maccarrone, Miriam Ulivi, Leonardo Orlandi, Giovanni Giannini, Nicola Gialdini, Gino Tassinari, Tiziana De Lodovici, Maria Luisa Bono, Giorgio Rueckert, Christina Baldi, Antonio D'Anna, Sebastiano Toni, Danilo Letteri, Federica Giuntini, Martina Lotti, Enrico Maria Flomin, Yuriy Pieroni, Alessio Kargiotis, Odysseas Karapanayiotides, Theodore Monaco, Serena Baronello, Mario Maimone Csiba László (1952-) (neurológus, pszichiáter) Szabó Lilla (1976-) (egyetemi tanár) Chiti, Alberto Giorli, Elisa Del Sette, Massimo Imberti, Davide Zabzuni, Dorjan Doronin, Boris Volodina, Vera Michel, Patrik Vanacker, Peter Barlinn, Kristian Pallesen, Lars-Peder Barlinn, Jessica Deleu, Dirk Melikyan, Gayane Ibrahim, Faisal Akhtar, Naveed Gourbali, Vanessa Paciaroni, Maurizio
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2.

001-es BibID:BIBFORM117248
035-os BibID:(cikkazonosító)100782 (Scopus)85178352005
Első szerző:de Jonge, Jeroen C.
Cím:Prevention of infections and fever to improve outcome in older patients with acute stroke (PRECIOUS) : a randomised, open, phase III, multifactorial, clinical trial with blinded outcome assessment / de Jonge Jeroen C., Sluis Wouter M., Reinink Hendrik, Bath Philip M., Woodhouse Lisa J., Zweedijk Berber, van de Beek Diederik, Aamodt Anne Hege, Alpers Iris, Ciccone Alfonso, Csiba Laszlo, Demotes Jacques, Korv Janika, Kurkowska-Jastrzebska Iwona, Dawson Jesse, Macleod Malcolm R., Ntaios George, Poli Sven, Milionis Haralampos, Ricci Stefano, Cenciarelli Silvia, Candelaresi Paolo, de Bruijn Sebastiaan F. T. M., Pathansali Rohan, Krishnan Kailash, Clarke Brian, Thomalla Götz, van der Worp H. Bart, PRECIOUS investigators
Dátum:2024
ISSN:2666-7762
Megjegyzések:Background: Infections and fever after stroke are associated with poor functional outcome or death. We assessed whether prophylactic treatment with anti-emetic, antibiotic, or antipyretic medication would improve functional outcome in older patients with acute stroke. Methods: We conducted an international, 2?2?2-factorial, randomised, controlled, open-label trial with blinded outcome assessment in patients aged 66 years or older with acute ischaemic stroke or intracerebral haemorrhage and a score on the National Institutes of Health Stroke Scale ? 6. Patients were randomly allocated (1:1) to metoclopramide (oral, rectal, or intravenous; 10 mg thrice daily) vs. no metoclopramide, ceftriaxone (intravenous; 2000 mg once daily) vs. no ceftriaxone, and paracetamol (oral, rectal, or intravenous; 1000 mg four times daily) vs. no paracetamol, started within 24 h after symptom onset and continued for four days. All participants received standard of care. The target sample size was 3800 patients. The primary outcome was the score on the modified Rankin Scale (mRS) at 90 days analysed with ordinal logistic regression and reported as an adjusted common odds ratio (an acOR < 1 suggests benefit and an acOR > 1 harm). This trial is registered (ISRCTN82217627). Findings: From April 2016 through June 2022, 1493 patients from 67 European sites were randomised to metoclopramide (n = 704) or no metoclopramide (n = 709), ceftriaxone (n = 594) or no ceftriaxone (n = 482), and paracetamol (n = 706) or no paracetamol (n = 739), of whom 1471 were included in the intention-to-treat analysis. Prophylactic use of study medication did not significantly alter the primary outcome at 90 days: metoclopramide vs. no metoclopramide (adjusted common odds ratio [acOR], 1.01; 95% CI 0.81?1.25), ceftriaxone vs. no ceftriaxone (acOR 0.99; 95% CI 0.77?1.27), paracetamol vs. no paracetamol (acOR 1.19; 95% CI 0.96?1.47). The study drugs were safe and not associated with an increased incidence of serious adverse events. Interpretation: We observed no sign of benefit of prophylactic use of metoclopramide, ceftriaxone, or paracetamol during four days in older patients with a moderately severe to severe acute stroke. Funding: This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No: 634809.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Fever
Infection
Intracerebral haemorrhage
Ischaemic stroke
Pneumonia
Stroke
Megjelenés:The Lancet Regional Health - Europe. - 36 (2024), p. 1-15. -
További szerzők:Sluis, Wouter M. Reinink, Hendrik Bath, Philip M. Woodhouse, Lisa J. Zweedijk, Berber van de Beek, Diederik Aamodt, Anne Hege Alpers, Iris Ciccone, Alfonso Csiba László (1952-) (neurológus, pszichiáter) Demotes-Mainard, Jacques Kõrv, Janika Kurkowska-Jastrzebska, Iwona Dawson, Jesse Macleod, Malcolm R. Ntaios, George Poli, Sven Milionis, Haralampos Ricci, Stefano Cenciarelli, Silvia Candelaresi, Paolo de Bruijn, Sebastiaan F. T. M. Pathansali, Rohan Krishnan, Kailash Clarke, Brian Thomalla, Götz van der Worp, H. Bart PRECIOUS investigators
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3.

001-es BibID:BIBFORM106777
035-os BibID:(scopus)85103595509 (wos)000635996200001
Első szerző:de Jonge, Jeroen C.
Cím:Regulatory delays in a multinational clinical stroke trial / de Jonge Jeroen C., Reinink Hendrik, Colam Bridget, Alpers Iris, Ciccone Alfonso, Csiba Laszlo, Korv Janika, Kurkowska-Jastrzebska Iwona, Macleod Malcolm R., Ntaios George, Thomalla Götz, Bath Philip M., van der Worp H. Bart
Dátum:2021
ISSN:2396-9873 2396-9881
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:European Stroke Journal. - 6 : 2 (2021), p. 120-127. -
További szerzők:Reinink, Hendrik Colam, Bridget Alpers, Iris Ciccone, Alfonso Csiba László (1952-) (neurológus, pszichiáter) Kõrv, Janika Kurkowska-Jastrzebska, Iwona Macleod, Malcolm R. Ntaios, George Thomalla, Götz Bath, Philip M. van der Worp, H. Bart
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4.

001-es BibID:BIBFORM090997
Első szerző:Paciaroni, Maurizio
Cím:Early recurrence in paroxysmal versus sustained atrial fibrillation in patients with acute ischaemic stroke / Maurizio Paciaroni, Filippo Angelini, Giancarlo Agnelli, Georgios Tsivgoulis, Karen L. Furie, Prasanna Tadi, Cecilia Becattini, Nicola Falocci, Marialuisa Zedde, Azmil H. Abdul-Rahim, Kennedy R. Lees, Andrea Alberti, Michele Venti, Monica Acciarresi, Riccardo Altavilla, Cataldo D'Amore, Maria G. Mosconi, Ludovica A. Cimini, Paolo Bovi, Monica Carletti, Alberto Rigatelli, Manuel Cappellari, Jukka Putaala, Liisa Tomppo, Turgut Tatlisumak, Fabio Bandini, Simona Marcheselli, Alessandro Pezzini, Loris Poli, Alessandro Padovani, Luca Masotti, Vieri Vannucchi, Sung-Il Sohn, Gianni Lorenzini, Rossana Tassi, Francesca Guideri, Maurizio Acampa, Giuseppe Martini, George Ntaios, Efstathia Karagkiozi, George Athanasakis, Kostantinos Makaritsis, Kostantinos Vadikolias, Chrysoula Liantinioti, Maria Chondrogianni, Nicola Mumoli, Domenico Consoli, Franco Galati, Simona Sacco, Antonio Carolei, Cindy Tiseo, Francesco Corea, Walter Ageno, Marta Bellesini, Giorgio Silvestrelli, Alfonso Ciccone, Umberto Scoditti, Licia Denti, Michelangelo Mancuso, Miriam Maccarrone, Giovanni Orlandi, Nicola Giannini, Gino Gialdini, Tiziana Tassinari, Maria Luisa De Lodovici, Giorgio Bono, Christina Rueckert, Antonio Baldi, Danilo Toni, Federica Letteri, Martina Giuntini, Enrico M. Lotti, Yuriy Flomin, Alessio Pieroni, Odysseas Kargiotis, Theodore Karapanayiotides, Serena Monaco, Mario M. Baronello, Laszló Csiba, Lilla Szabó, Alberto Chiti, Elisa Giorli, Massimo Del Sette, Davide Imberti, Dorjan Zabzuni, Boris Doronin, Vera Volodina, Patrik Michel Pd-Mer, Peter Vanacker, Kristian Barlinn, Lars-P. Pallesen, Jessica Kepplinger, Dirk Deleu, Gayane Melikyan, Faisal Ibrahim, Naveed Akhtar, Vanessa Gourbali, Shadi Yaghi, Valeria Caso
Dátum:2019
ISSN:2396-9873 2396-9881
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:European Stroke Journal. - 4 : 1 (2019), p. 55-64. -
További szerzők:Angelini, Filippo Agnelli, Giancarlo Tsivgoulis, Georgios Furie, Karen L. Tadi, Prasanna Becattini, Cecilia Falocci, Nicola Zedde, Marialuisa Abdul-Rahim, Azmil H. Lees, Kennedy R. Alberti, Andrea Venti, Michele Acciarresi, Monica Altavilla, Riccardo D'Amore, Cataldo Mosconi, Maria Giulia Cimini, Ludovica Anna Bovi, Paolo Carletti, Monica Rigatelli, Alberto Cappellari, Manuel Putaala, Jukka Tomppo, Liisa Tatlisumak, Turgut Bandini, Fabio Marcheselli, Simona Pezzini, Alessandro Poli, Loris Padovani, Alessandro Masotti, Luca Vannucchi, Vieri Sohn, Sung-Il Lorenzini, Gianni Tassi, Rossana Guideri, Francesca Acampa, Maurizio Martini, Giuseppe Ntaios, George Karagkiozi, Efstathia Athanasakis, George Makaritsis, Kostantinos Vadikolias, Kostantinos Liantinioti, Chrissoula Chondrogianni, Maria Mumoli, Nicola Consoli, Domenico Galati, Franco Sacco, Simona Carolei, Antonio Tiseo, Cindy Corea, Francesco Ageno, Walter Bellesini, Marta Silvestrelli, Giorgio Ciccone, Alfonso Scoditti, Umberto Denti, Licia Mancuso, Michelangelo Maccarrone, Miriam Orlandi, Giovanni Giannini, Nicola Gialdini, Gino Tassinari, Tiziana De Lodovici, Maria Luisa Bono, Giorgio Rueckert, Christina Baldi, Antonio Toni, Danilo Letteri, Federica Giuntini, Martina Lotti, Enrico Maria Flomin, Yuriy Pieroni, Alessio Kargiotis, Odysseas Karapanayiotides, Theodore Monaco, Serena Baronello, Mario Maimone Csiba László (1952-) (neurológus, pszichiáter) Szabó Lilla (1976-) (egyetemi tanár) Chiti, Alberto Giorli, Elisa Del Sette, Massimo Imberti, Davide Zabzuni, Dorjan Doronin, Boris Volodina, Vera Michel Pd-Mer, Patrik Vanacker, Peter Barlinn, Kristian Pallesen, Lars-Peder Kepplinger, Jessica Deleu, Dirk Melikyan, Gayane Ibrahim, Faisal Akhtar, Naveed Gourbali, Vanessa Yaghi, Shadi Caso, Valeria
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5.

001-es BibID:BIBFORM090996
Első szerző:Paciaroni, Maurizio
Cím:Hemorrhagic Transformation in Patients With Acute Ischemic Stroke and Atrial Fibrillation : time to Initiation of Oral Anticoagulant Therapy and Outcomes / Paciaroni Maurizio, Bandini Fabio, Agnelli Giancarlo, Tsivgoulis Georgios, Yaghi Shadi, Furie Karen L., Tadi Prasanna, Becattini Cecilia, Zedde Marialuisa, Abdul-Rahim Azmil H., Lees Kennedy R., Alberti Andrea, Venti Michele, Acciarresi Monica, D'Amore Cataldo, Mosconi Maria Giulia, Cimini Ludovica Anna, Altavilla Riccardo, Volpi Giacomo, Bovi Paolo, Carletti Monica, Rigatelli Alberto, Cappellari Manuel, Putaala Jukka, Tomppo Liisa, Tatlisumak Turgut, Marcheselli Simona, Pezzini Alessandro, Poli Loris, Padovani Alessandro, Masotti Luca, Vannucchi Vieri, Sohn Sung-Il, Lorenzini Gianni, Tassi Rossana, Guideri Francesca, Acampa Maurizio, Martini Giuseppe, Ntaios George, Athanasakis George, Makaritsis Konstantinos, Karagkiozi Efstathia, Vadikolias Konstantinos, Liantinioti Chrissoula, Chondrogianni Maria, Mumoli Nicola, Consoli Domenico, Galati Franco, Sacco Simona, Carolei Antonio, Tiseo Cindy, Corea Francesco, Ageno Walter, Bellesini Marta, Colombo Giovanna, Silvestrelli Giorgio, Ciccone Alfonso, Lanari Alessia, Scoditti Umberto, Denti Licia, Mancuso Michelangelo, Maccarrone Miriam, Ulivi Leonardo, Orlandi Giovanni, Giannini Nicola, Gialdini Gino, Tassinari Tiziana, De Lodovici Maria Luisa, Bono Giorgio, Rueckert Christina, Baldi Antonio, D'Anna Sebastiano, Toni Danilo, Letteri Federica, Giuntini Martina, Lotti Enrico Maria, Flomin Yuriy, Pieroni Alessio, Kargiotis Odysseas, Karapanayiotides Theodore, Monaco Serena, Baronello Mario Maimone, Csiba Laszló, Szabó Lilla, Chiti Alberto, Giorli Elisa, Del Sette Massimo, Imberti Davide, Zabzuni Dorjan, Doronin Boris, Volodina Vera, Michel Patrik, Vanacker Peter, Barlinn Kristian, Pallesen Lars-Peder, Barlinn Jessica, Deleu Dirk, Melikyan Gayane, Ibrahim Faisal, Akhtar Naveed, Gourbali Vanessa, Caso Valeria
Dátum:2018
ISSN:2047-9980
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Journal of the American Heart Association. - 7 : 22 (2018), p. 1-10. -
További szerzők:Bandini, Fabio Agnelli, Giancarlo Tsivgoulis, Georgios Yaghi, Shadi Furie, Karen L. Tadi, Prasanna Becattini, Cecilia Zedde, Marialuisa Abdul-Rahim, Azmil H. Lees, Kennedy R. Alberti, Andrea Venti, Michele Acciarresi, Monica D'Amore, Cataldo Mosconi, Maria Giulia Cimini, Ludovica Anna Altavilla, Riccardo Volpi, Giacomo Bovi, Paolo Carletti, Monica Rigatelli, Alberto Cappellari, Manuel Putaala, Jukka Tomppo, Liisa Tatlisumak, Turgut Marcheselli, Simona Pezzini, Alessandro Poli, Loris Padovani, Alessandro Masotti, Luca Vannucchi, Vieri Sohn, Sung-Il Lorenzini, Gianni Tassi, Rossana Guideri, Francesca Acampa, Maurizio Martini, Giuseppe Ntaios, George Athanasakis, George Makaritsis, Kostantinos Karagkiozi, Efstathia Vadikolias, Kostantinos Liantinioti, Chrissoula Chondrogianni, Maria Mumoli, Nicola Consoli, Domenico Galati, Franco Sacco, Simona Carolei, Antonio Tiseo, Cindy Corea, Francesco Ageno, Walter Bellesini, Marta Colombo, Giovanna Silvestrelli, Giorgio Ciccone, Alfonso Lanari, Alessia Scoditti, Umberto Denti, Licia Mancuso, Michelangelo Maccarrone, Miriam Ulivi, Leonardo Orlandi, Giovanni Giannini, Nicola Gialdini, Gino Tassinari, Tiziana De Lodovici, Maria Luisa Bono, Giorgio Rueckert, Christina Baldi, Antonio D'Anna, Sebastiano Toni, Danilo Letteri, Federica Giuntini, Martina Lotti, Enrico Maria Flomin, Yuriy Pieroni, Alessio Kargiotis, Odysseas Karapanayiotides, Theodore Monaco, Serena Baronello, Mario Maimone Csiba László (1952-) (neurológus, pszichiáter) Szabó Lilla (1976-) (egyetemi tanár) Chiti, Alberto Giorli, Elisa Del Sette, Massimo Imberti, Davide Zabzuni, Dorjan Doronin, Boris Volodina, Vera Michel, Patrik Vanacker, Peter Barlinn, Kristian Pallesen, Lars-Peder Barlinn, Jessica Deleu, Dirk Melikyan, Gayane Ibrahim, Faisal Akhtar, Naveed Gourbali, Vanessa Caso, Valeria
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6.

001-es BibID:BIBFORM067757
Első szerző:Paciaroni, Maurizio
Cím:Prediction of Early Recurrent Thromboembolic Event and Major Bleeding in Patients With Acute Stroke and Atrial Fibrillation by a Risk Stratification Schema / Maurizio Paciaroni, Giancarlo Agnelli, Valeria Caso, Georgios Tsivgoulis, Karen L. Furie, Prasanna Tadi, Cecilia Becattini, Nicola Falocci, Marialuisa Zedde, Azmil H. Abdul-Rahim, Kennedy R. Lees, Andrea Alberti, Michele Venti, Monica Acciarresi, Cataldo D'Amore, Maria Giulia Mosconi, Ludovica Anna Cimini, Antonio Procopio, Paolo Bovi, Monica Carletti, Alberto Rigatelli, Manuel Cappellari, Jukka Putaala, Liisa Tomppo, Turgut Tatlisumak, Fabio Bandini, Simona Marcheselli, Alessandro Pezzini, Loris Poli, Alessandro Padovani, Luca Masotti, Vieri Vannucchi, Sung-Il Sohn, Gianni Lorenzini, Rossana Tassi, Francesca Guideri, Maurizio Acampa, Giuseppe Martini, George Ntaios, Efstathia Karagkiozi, George Athanasakis, Kostantinos Makaritsis, Kostantinos Vadikolias, Chrysoula Liantinioti, Maria Chondrogianni, Nicola Mumoli, Domenico Consoli, Franco Galati, Simona Sacco, Antonio Carolei, Cindy Tiseo, Francesco Corea, Walter Ageno, Marta Bellesini, Giovanna Colombo, Giorgio Silvestrelli, Alfonso Ciccone, Umberto Scoditti, Licia Denti, Michelangelo Mancuso, Miriam Maccarrone, Giovanni Orlandi, Nicola Giannini, Gino Gialdini, Tiziana Tassinari, Maria Luisa De Lodovici, Giorgio Bono, Christina Rueckert, Antonio Baldi, Sebastiano D'Anna, Danilo Toni, Federica Letteri, Martina Giuntini, Enrico Maria Lotti, Yuriy Flomin, Alessio Pieroni, Odysseas Kargiotis, Theodore Karapanayiotides, Serena Monaco, Mario Maimone Baronello, Laszló Csiba, Lilla Szabó, Alberto Chiti, Elisa Giorli, Massimo Del Sette, Davide Imberti, Dorjan Zabzuni, Boris Doronin, Vera Volodina, Patrik Michel, Peter Vanacker, Kristian Barlinn, Lars-Peder Pallesen, Jessica Kepplinger, Ulf Bodechtel, Johannes Gerber, Dirk Deleu, Gayane Melikyan, Faisal Ibrahim, Naveed Akhtar, Vanessa Gourbali, Shadi Yaghi
Dátum:2017
ISSN:0039-2499
Megjegyzések:Background and PurposesThis study was designed to derive and validate a score to predict early ischemic events and major bleedings after an acute ischemic stroke in patients with atrial fibrillation.MethodsThe derivation cohort consisted of 854 patients with acute ischemic stroke and atrial fibrillation included in prospective series between January 2012 and March 2014. Older age (hazard ratio 1.06 for each additional year; 95% confidence interval, 1.00?1.11) and severe atrial enlargement (hazard ratio, 2.05; 95% confidence interval, 1.08?2.87) were predictors for ischemic outcome events (stroke, transient ischemic attack, and systemic embolism) at 90 days from acute stroke. Small lesions (?1.5 cm) were inversely correlated with both major bleeding (hazard ratio, 0.39; P=0.03) and ischemic outcome events (hazard ratio, 0.55; 95% confidence interval, 0.30?1.00). We assigned to age ?80 years 2 points and between 70 and 79 years 1 point; ischemic index lesion >1.5 cm, 1 point; severe atrial enlargement, 1 point (ALESSA score). A logistic regression with the receiver-operating characteristic graph procedure (C statistic) showed an area under the curve of 0.697 (0.632?0.763; P=0.0001) for ischemic outcome events and 0.585 (0.493?0.678; P=0.10) for major bleedings.ResultsThe validation cohort consisted of 994 patients included in prospective series between April 2014 and June 2016. Logistic regression with the receiver-operating characteristic graph procedure showed an area under the curve of 0.646 (0.529?0.763; P=0.009) for ischemic outcome events and 0.407 (0.275?0.540; P=0.14) for hemorrhagic outcome events.ConclusionsIn acute stroke patients with atrial fibrillation, high ALESSA scores were associated with a high risk of ischemic events but not of major bleedings.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
atrial fibrillation
myocardial infarction
risk stratification
stroke
Megjelenés:Stroke 48 : 3 (2017), p. 726-732. -
További szerzők:Agnelli, Giancarlo Caso, Valeria Tsivgoulis, Georgios Furie, Karen L. Tadi, Prasanna Becattini, Cecilia Falocci, Nicola Zedde, Marialuisa Abdul-Rahim, Azmil H. Lees, Kennedy R. Alberti, Andrea Venti, Michele Acciarresi, Monica D'Amore, Cataldo Mosconi, Maria Giulia Cimini, Ludovica Anna Procopio, Antonio Bovi, Paolo Carletti, Monica Rigatelli, Alberto Cappellari, Manuel Putaala, Jukka Tomppo, Liisa Tatlisumak, Turgut Bandini, Fabio Marcheselli, Simona Pezzini, Alessandro Poli, Loris Padovani, Alessandro Masotti, Luca Vannucchi, Vieri Sohn, Sung-Il Lorenzini, Gianni Tassi, Rossana Guideri, Francesca Acampa, Maurizio Martini, Giuseppe Ntaios, George Karagkiozi, Efstathia Athanasakis, George Makaritsis, Kostantinos Vadikolias, Kostantinos Liantinioti, Chrissoula Chondrogianni, Maria Mumoli, Nicola Consoli, Domenico Galati, Franco Sacco, Simona Carolei, Antonio Tiseo, Cindy Corea, Francesco Ageno, Walter Bellesini, Marta Colombo, Giovanna Silvestrelli, Giorgio Ciccone, Alfonso Scoditti, Umberto Denti, Licia Mancuso, Michelangelo Maccarrone, Miriam Orlandi, Giovanni Giannini, Nicola Gialdini, Gino Tassinari, Tiziana De Lodovici, Maria Luisa Bono, Giorgio Rueckert, Christina Baldi, Antonio D'Anna, Sebastiano Toni, Danilo Letteri, Federica Giuntini, Martina Lotti, Enrico Maria Flomin, Yuriy Pieroni, Alessio Kargiotis, Odysseas Karapanayiotides, Theodore Monaco, Serena Baronello, Mario Maimone Csiba László (1952-) (neurológus, pszichiáter) Szabó Lilla (1976-) (egyetemi tanár) Chiti, Alberto Giorli, Elisa Del Sette, Massimo Imberti, Davide Zabzuni, Dorjan Doronin, Boris Volodina, Vera Michel, Patrik Vanacker, Peter Barlinn, Kristian Pallesen, Lars-Peder Kepplinger, Jessica Bodechtel, Ulf Gerber, Johannes Deleu, Dirk Melikyan, Gayane Ibrahim, Faisal Akhtar, Naveed Gourbali, Vanessa Yaghi, Shadi
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001-es BibID:BIBFORM090999
Első szerző:Reinink, Hendrik
Cím:PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke. Rationale and design of a randomised, open, phase III, clinical trial with blinded outcome assessment / Hendrik Reinink, Jeroen C. de Jonge, Philip M. Bath, Diederik van de Beek, Eivind Berge, Saskia Borregaard, Alfonso Ciccone, Laszlo Csiba, Jacques Demotes, Diederik W. Dippel, Janika Kõrv, Iwona Kurkowska-Jastrzebska, Kennedy R. Lees, Malcolm R. Macleod, George Ntaios, Gary Randall, Götz Thomalla, H. Bart van der Worp
Dátum:2018
ISSN:2396-9873 2396-9881
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:European Stroke Journal. - 3 : 3 (2018), p. 291-298. -
További szerzők:de Jonge, Jeroen C. Bath, Philip M. van de Beek, Diederik Berge, Eivind Borregaard, Saskia Ciccone, Alfonso Csiba László (1952-) (neurológus, pszichiáter) Demotes-Mainard, Jacques Dippel, Diederik W. Körv, Janika Kurkowska-Jastrzebska, Iwona Lees, Kennedy R. Macleod, Malcolm R. Ntaios, George Randall, Gary Thomalla, Götz van der Worp, H. Bart
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