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001-es BibID:bibEBI00026266
Első szerző:Majer Réka
Cím:Neuropsychiatric symptoms, quality of life and caregivers' burden in dementia / Majer Réka, Adeyi Olar, Bagoly Zsuzsa, Simon Viktória, Csiba László, Kardos László, Hortobágyi Tibor, Frecska Ede
Dátum:2020
ISSN:2391-5463 1911-2092
Megjegyzések:The objective of this research is to identify the relationship between the neuropsychiatric symptoms (NPSs) of patients with major neurocognitive disorder (mNCD), their quality of life, illness intrusiveness and the caregiver's burden. We assessed 131 patients with mNCD. Examination methods included WHO well-being index short version, illness intrusiveness rating scale, Alzheimer's Disease Assessment Scale-Cog, Mini Mental State Examination and neuropsychiatric inventory. The results were analysed using standard statistical tests. In our sample, the prevalence of NPSs is 100%. A significant correlation (p < 0.0001) was observed with quality of life and illness intrusiveness. Additionally, a strong relationship was observed between NPSs and the caregiver's burden (r = 0.9). The result is significantly twice as much stronger in comparison to the relationship between NPS and cognitive symptoms (r = 0.4). This is the first study in Hungary to assess the impact of NPS on the burden of relatives and quality of life. NPS had twice stronger impact on caregivers' burden than cognitive decline. However, further studies are needed to assess the sub-syndromes in mNCD in relation to NPS.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Open Medicine. - 15 : 1 (2020), p. 905-914. -
További szerzők:Adeyi, Olar Bagoly Zsuzsa (1978-) (orvos) Simon Viktória Csiba László (1952-) (neurológus, pszichiáter) Kardos László (1970-) (megelőző orvostan és népegészségtan szakorvos) Hortobágyi Tibor (1965-) (patológus) Frecska Ede (1953-) (pszichiáter)
Pályázati támogatás:GINOP-2.3.2-15-2016-00048
GINOP
SZTE ÁOK-KKA No. 5S 567 (A202)
Egyéb
OTKA-NKFIH-SNN 132999
OTKA
K120042 Nemzeti Kutatási, Fejlesztési és Innovációs Alap
Egyéb
Nemzeti Agykutatási Program 2.0 (2017-1.2.1-NKP-2017-00002
Egyéb
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
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2.

001-es BibID:BIBFORM078918
035-os BibID:(PMID)30997394
Első szerző:Majer Réka
Cím:Behavioural and Psychological Symptoms in Neurocognitive Disorders : specific Patterns in Dementia Subtypes / Réka Majer, Viktória Simon, László Csiba, László Kardos, Ede Frecska, Tibor Hortobágyi
Dátum:2019
ISSN:2391-5463
Megjegyzések:BACKGROUND: Behavioural and psychological symptoms in dementia (BPSD) form an important sub-syndrome of dementia. We assessed the frequency and severity of BPSD in a random sample of Hungarian treatment-naïve dementia patients. Furthermore, we examined the relationship between cognitive symptoms and BPSD and the pattern of BPSD in specific types of dementias. METHODS: Patients (n=131) were classified into 3 groups: Alzheimer's (AD), vascular (VD), and mixed (MD) dementia. The Mini-Mental State Examination (MMSE), Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) and Neuropsychiatric Inventory (NPI) neuropsychological tests were employed. RESULTS: Mean age and MMSE score did not differ significantly among groups. BPSD was frequent (100% prevalence, NPI mean total Frequency score: 14.58, SD=7.55); abnormal motor behaviour showed the highest frequency. Hallucinations and delusions were related to the aetiology of dementia and were independent of the level of cognitive deterioration, whereas irritability, sleep-wake cycle dysfunctions, and eating-appetite change were associated with cognitive deterioration and were independent from aetiology. Both aberrant motor behaviour and disinhibition were significantly associated with aetiology and cognitive deterioration. CONCLUSIONS: BPSD symptoms are significant constituents of dementia syndromes, affecting quality of life and substantially contributing to the caregiver's burden. Specific symptom patterns can be identified in different types of dementia.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Alzheimer's disease
Behaviour and psychological symptoms in dementia (BPSD)
Dementia
Neurocognitive disorder
Vascular dementia
Megjelenés:Open Medicine. - 14 : 1 (2019), p. 307-316. -
További szerzők:Simon Viktória Csiba László (1952-) (neurológus, pszichiáter) Kardos László (1898-1987) (irodalomtörténész, műfordító) Frecska Ede (1953-) (pszichiáter) Hortobágyi Tibor (1965-) (patológus)
Internet cím:Szerző által megadott URL
DOI
Intézményi repozitóriumban (DEA) tárolt változat
Borító:
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