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001-es BibID:	BIBFORM100407
Első szerző:	Kolozsvári Rudolf (kardiológus)
Cím:	Fractional Flow Reserve-Guided Stenting of Epicardial Collateral Channel in Chronic Left Main Total Occlusion / Kolozsvári Rudolf, Bakk Sándor, Tar Balázs, Rácz Ágnes, Szabó Gábor Tamás, Kőszegi Zsolt
Dátum:	2021
ISSN:	1553-8389 1878-0938
Tárgyszavak:	Orvostudományok Klinikai orvostudományok szerkesztőségi anyag folyóiratcikk
Megjelenés:	Cardiovascular Revascularization Medicine. - 33 (2021), p. 68-69. -
További szerzők:	Bakk Sándor Tar Balázs (1970-) (orvos) Rácz Ágnes (1983-) (orvos) Szabó Gábor Tamás (1982-) (kardiológus) Kőszegi Zsolt (1962-) (kardiológus, belgyógyász)
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001-es BibID:	BIBFORM037173
Első szerző:	Kőszegi Zsolt (kardiológus, belgyógyász)
Cím:	Calculation the Translesional Pressure Gradients on Coronary Stenosis by Combining Three-dimensional Coronary Angiography Parameters with Frame Count Data / Kőszegi Zs., Tar B., Ember S., Lugosi P., Béres Z., Sánta J., Sváb M., Bakk S., Kolozsvári R., Polgár P.
Dátum:	2011
Megjegyzések:	Background: Assessing the hemodynamic impact of anintermediate coronary artery stenosis on the basis of thediameter stenosis is often ambiguous. Measurement of thefractional flow reserve (FFR) is necessary in these casesfor correct clinical decision making.Aim: Determining the tranlesional pressure gradients,based on the data calculated from the 3D coronaryangiography and the frame count method using classicfluid dynamic equations and to compare them with themeasured values.Methods: FFR measurements were performed on 15coronary segments of 10 patients by PressureWire?Certus. 3D reconstructions of the same segments wereperformed by the IC30 software (Siemens), and the crosssectionalarea stenosis (AS) (%), the length of the lesion(L) (mm), the minimal lumen area (MLA) (mm2), theplaque volume (PV) (%) and the distal reference area(dRefA) (mm2) were determined. The flow velocity (mm/s)was assessed by the frame count on the coronaryangiography following administration of 6 ml contrastmaterial with a 3ml/s rate by ACIST? Injection System(BBraun). Vessel length was determined on the 3Dreconstruction. Pressure gradients (Hgmm) werecalculated on the basis of the fluid dynamic equations:dP= Q(Rp+QRt), where Rp= 0,75 x L / MLA2and Rt = 3,76x (1/MLA - 1/dRef A)2,Q(volumetric flow)(ml/s) = flow velocity x dRefA.Results: Regression analysis has demonstratedsignificant relationship between the calculated andmeasured resting distal/proximal pressure ratio (r=0.66;p=0.007). Tight correlation has been found between thecalculated and measured FFR (assuming twofoldvolumetric flow during vasodilatation) (r=0.88;p<0.001). Among the 3D parameters only the AS and thePV showed significant correlation with the FFR (r=0.62and 0.71; p=0.013 and 0.003, respectively).Conclusions: The calculation of pressure gradients byfluid dynamic equations using 3D coronary angiographyand frame count data can predict the functional flowconsequence of a stenosis.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban FFR measurements IC30 software
Megjelenés:	Computing in Cardiology [electronic resource]. - 38 (2011), p. 729-732. -
További szerzők:	Tar B. Ember Sándor Lugosi P. Béres Z. Sánta J. Sváb Marianna Bakk Sándor Kolozsvári Rudolf (1976-) (kardiológus) Polgár Péter
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001-es BibID:	BIBFORM077761
035-os BibID:	(WoS)000447836900019 (Scopus)85054145606
Első szerző:	Tar Balázs (orvos)
Cím:	Less invasive fractional flow reserve measurement from 3-dimensional quantitative coronary angiography and classic fluid dynamic equations / Balazs Tar, Csaba Jenei, Csaba Andras Dezsi, Sandor Bakk, Zoltan Beres, Janos Santa, Marianna Svab, Veronika Szentes, Peter Polgar, Csaba Bujaky, Daniel Czuriga, Zsolt Kőszegi
Dátum:	2018
ISSN:	1774-024X 1969-6213
Megjegyzések:	AIMS: The aim of this study was to develop a simplified model of FFR calculation (FFRsim) derived from three-dimensional (3D) coronary angiographic data and classic fluid dynamic equations without using finite element analysis. METHODS AND RESULTS: Intracoronary pressure measurements were performed by pressure wire sensors. The lumens of the interrogated vessel segments were reconstructed in 3D. The coronary artery volumetric flow was calculated based on the velocity of the contrast material. Pressure gradients were computed by classic fluid dynamic equations. The diagnostic power of the simplified computation of the FFR (FFRsim) was assessed by comparing the results with standard invasive FFR measurements (FFRmeas) in 68 vessels with a single stenosis. We found a strong correlation between the FFRsim and the FFRmeas (r=0.86, p<0.0001). The sensitivity and specificity for predicting the abnormal FFR of ?0.80 (indicating haemodynamically significant stenosis) were 90% and 100%, respectively. The area under the curve (AUC) was 0.96. To achieve 100% negative and positive predictive values we defined the FFRsim >0.88 and the FFRsim ?0.8 ranges. In our patient population, these ranges were found in 69% of the cases. CONCLUSIONS: According to our simplified model, the invasive FFR measurement can be omitted without misclassification in pre-specified ranges of the calculated FFRsim.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	EuroIntervention. - 14 : 8 (2018), p. 942-950. -
További szerzők:	Jenei Csaba (1976-) (kardiológus) Dézsi Csaba András Bakk Sándor Béres Zoltán Sánta János (1987-) Sváb Marianna Szentes Veronika Polgár Péter Bujáky Csaba Czuriga Dániel (1982-) (kardiológus) Kőszegi Zsolt (1962-) (kardiológus, belgyógyász)
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