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1.

001-es BibID:BIBFORM029938
Első szerző:Bereczki Dániel (neurológus)
Cím:Cochrane Report : a systematic review of mannitol therapy for acute ischemic Stroke and cerebral parenchymal Hemorrhage / Bereczki, D., Liu, M., do Prado, G. F., Fekete, I.
Dátum:2000
ISSN:0039-2499
Megjegyzések:Background?Mannitol was reported to decrease cerebral edema associated with tissue damage and is used to treat acute stroke in many countries.Summary of Review?We tested whether there is any evidence from unconfounded randomized clinical trials that treatment with mannitol reduces short- and long-term case fatality and dependency if administered after ischemic stroke or cerebral parenchymal hemorrhage. Trials were identified by the standard search strategy of the Cochrane Collaboration Stroke Review Group. A supplementary MEDLINE search was performed, and the Chinese Stroke Trials Register and the Latin-American databank LILACS were checked. A search was performed of master's and PhD degree theses in the databank of Sao Paulo University and in abstracts of medical congresses on neurology and neurosurgery during 1965?1997 in Brazil. Investigators were contacted for unpublished information. Only truly randomized unconfounded clinical trials were eligible for inclusion. Two of the reviewers independently extracted data from the trials. Data synthesis and analysis was performed with the use of the Cochrane Review Manager software (RevMan version 4.0.4).Conclusions?Only 1 trial fulfilled the inclusion criteria. The number of included patients was small, and the follow-up was short. Case fatality, the proportion of dependent patients, and side effects were not reported and were not available from the investigators. As a result of lack of appropriate randomized trials, currently no conclusion can be drawn on the effects of mannitol in acute stroke. The routine use of mannitol in all patients with acute stroke is not supported by evidence from randomized controlled clinical trials.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Stroke. - 31 : 11 (2000), p. 2719-2722. -
További szerzők:Liu, M. do Prado, G. F. Fekete István (1951-) (neurológus, pszichiáter)
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2.

001-es BibID:BIBFORM030011
Első szerző:Bereczki Dániel (neurológus)
Cím:Osmotherapy : a call to arms (Respone) / Bereczki D., Fekete I., Liu M., do Prado G. F.
Dátum:2001
ISSN:0039-2499
Tárgyszavak:Orvostudományok Klinikai orvostudományok szerkesztői levél
Megjelenés:Stroke. - 32 (2001), p. 812. -
További szerzők:Fekete István (1951-) (neurológus, pszichiáter) Liu, M. do Prado, G. F.
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3.

001-es BibID:BIBFORM029951
Első szerző:Bereczki Dániel (neurológus)
Cím:Mannitol use in acute stroke : case fatality at 30 days and 1 year / Bereczki D., Mihálka L., Szatmári S., Fekete K., Di Cesar D., Fülesdi B., Csiba L., Fekete I.
Dátum:2003
ISSN:0039-2499
Megjegyzések:BACKGROUND AND PURPOSE: Mannitol is used worldwide to treat acute stroke, although its efficacy and safety have not been proven by randomized trials.METHODS:In a tricenter, prospective study, we analyzed the 30-day and 1-year case fatality with respect to mannitol treatment status in 805 patients consecutively admitted within 72 hours of stroke onset. Confounding factors were compared between treated and nontreated patients.RESULTS:Two thirds of the patients received intravenous mannitol as part of their routine treatment (mean dose, 47+/-22 g/d; mean duration, 6+/-3 days). The case fatality was 25% versus 16% (P=0.006) at 30 days and 38% versus 25% (P<0.001) at 1 year in the-mannitol treated and nontreated groups, respectively. Mannitol treatment effect was adjusted for age, stroke severity, fever in the first 3 days, and aspirin treatment (for ischemic strokes) in logistic regression models. Depending on the factors entered into the model, either no effect or harm could be attributed to mannitol. When the analysis was restricted to those admitted within 24 hours (n=568), case fatality differed significantly only at 1 year (35% in treated and 26% in nontreated patients, P=0.044). Although the prognostic scores of the Scandinavian Neurological Stroke Scale were similar in treated and nontreated patients, both in ischemic and hemorrhagic strokes, the patient groups differed in several factors that might also have influenced survival.CONCLUSIONS:Based on the results of this study, no recommendations can be made on the use of mannitol in acute stroke, and properly randomized, controlled trials should be performed to come to a final conclusion.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Stroke. - 34 : 7 (2003), p. 1730-1735. -
További szerzők:Mihálka László (1950-) (neurológus) Szatmári Szabolcs (1960-) (neurológus) Fekete Klára (1978-) (neurológus) Di Cesar, D. Fülesdi Béla (1961-) (aneszteziológus) Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter)
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4.

001-es BibID:BIBFORM029952
Első szerző:Bereczki Dániel (neurológus)
Cím:Mannitol for Acute Stroke / Bereczki, D., Liu, M., Fernandes do Prado, G., Fekete, I.
Dátum:2008
ISSN:0039-2499
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Stroke. - 39 : 2 (2008), p. 512-513. -
További szerzők:Liu, M. Fernandes do Prado, G. Fekete István (1951-) (neurológus, pszichiáter)
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5.

001-es BibID:BIBFORM029953
Első szerző:Bereczki Dániel (neurológus)
Cím:Vinpocetine for Acute Ischemic Stroke / Bereczki, D., Fekete, I.
Dátum:2008
ISSN:0039-2499
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Stroke. - 39 : 8 (2008), p. 2404-2405. -
További szerzők:Fekete István (1951-) (neurológus, pszichiáter)
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6.

001-es BibID:BIBFORM010568
Első szerző:Bereczki Dániel (neurológus)
Cím:The Debrecen Stroke Database : demographic characteristics, risk factors, stroke severity and outcome in 8088 consecutive hospitalised patients with acute cerebrovascular disease / Bereczki D., Mihalka L., Fekete I., Valikovics A., Csepany T., Fulesdi B., Bajko Z., Szekeres C., Fekete K., Csiba L.
Dátum:2009
Megjegyzések:High stroke mortality in central-eastern European countries might be due to higher stroke incidence, more severe strokes or less effective acute care than in countries with lower mortality rate. Hospital databases usually yield more detailed information on risk factors, stroke severity and short-term outcome than population-based registries. Patients and methods The Debrecen Stroke Database, data of 8088 consecutively hospitalised patients with acute cerebrovascular disease in a single stroke centre in East Hungary between October 1994 and December 2006, is analysed. Risk factors were recorded and stroke severity on admission was scored by the Mathew stroke scale. The modified Glasgow outcome scale was used to describe patient condition at discharge. Results Mean age was 68713 years, 11.4% had haemorrhagic stroke. The rate of hypertension on admission was 79% in men, and 84% in women, 40.3%of men and 19.8%of women were smokers, and 34% of all patients had a previous cerebrovascular disease in their history. Case fatality was 14.9%, and 43% had some disability at discharge. Outcome at discharge was worse with higher age, higher glucose, higher blood pressure, higher white cell count and erythrocyte sedimentation rate and more severe clinical signs on admission. In multivariate analysis admission blood pressure lost its significance in predicting outcome. Conclusions In this large Hungarian stroke unit database hypertension on admission, smoking and previous cerebrovascular disease were more frequent than in most western databases. These findings indicate major opportunities for more efficient stroke prevention in this and probably other eastern European countries.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
acute
blood pressure
cerebral haemorrhage
epidemiology
ischaemic stroke
risk factors
Megjelenés:International Journal of Stroke. - 4 : 5 (2009), p. 335-339. -
További szerzők:Mihálka László (1950-) (neurológus) Fekete István (1951-) (neurológus, pszichiáter) Valikovics Attila Csépány Tünde (1956-) (neurológus, pszichiáter) Fülesdi Béla (1961-) (aneszteziológus) Bajkó Z. Szekeres C. Fekete Klára (1978-) (neurológus) Csiba László (1952-) (neurológus, pszichiáter)
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7.

001-es BibID:BIBFORM001496
Első szerző:Bereczki Dániel (neurológus)
Cím:The Seven Wonders of China in stroke therapy : fact or illusion? / Bereczki D.
Dátum:2007
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Stroke. - 38 (2007), p. 142. -
Internet cím:elektronikus változat
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elektronikus változat
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8.

001-es BibID:BIBFORM029943
Első szerző:Bessenyei Mónika (neurológus, csecsemő- és gyermekgyógyász)
Cím:Characteristics of 4 stroke scales for the detection of changes in clinical signs in the acute phase of stroke / Bessenyei, M., Fekete, I., Csiba, L., Bereczki, D.
Dátum:2001
ISSN:1052-3057
Megjegyzések:OBJECTIVES: Detection of minor changes in clinical signs of stroke may be of interest when evaluating treatment interventions. This study analyzes the internal structure of four frequently used stroke scales and compares them for their sensitivity to detect changes in neurologic signs in the first week after acute stroke.METHODS:A cohort of 77 hospitalized acute stroke patients was scored by the Mathew, the National Institutes of Health (NIH), the Scandinavian, and the Orgogozo scales within 48 hours of hospital admission and again 7 days later.RESULTS:Scores on different scales correlated well with each other (range of absolute value of Spearman R, .82-.91; P <.001 in all comparisons). Scales reflected significant changes from entry to reexamination: P = .0013 for the Scandinavian scale (P = .004 for prognostic and P = .009 for long-term items, respectively); P = .00009 for the Orgogozo scale; P = .000007 for the Mathew scale; and P < .000001 for the NIH scale. This difference in sensitivity coincided with the number of factors extracted by principal component analysis: higher sensitivity of a scale was associated with a larger number of factors. Initial scores differed significantly among patients who were discharged, patients who died, and patients who remained hospitalized 7 days after the first examination (Kruskal-Wallis ANOVA, P < .01 for all scales).CONCLUSIONS:There are considerable differences in the internal structure of the different scales as reflected by the different number of factors extracted from the scale items. The application of the NIH scale is recommended for the most sensitive detection of changes in stroke signs.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Journal of Stroke and Cerebrovascular Diseases. - 10 : 2 (2001), p. 70-78. -
További szerzők:Fekete István (1951-) (neurológus, pszichiáter) Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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9.

001-es BibID:BIBFORM050856
Első szerző:Czuriga-Kovács Katalin Réka (neurológus)
Cím:Silent brain infarction : a review of recent observations / Katalin Réka Kovács, Dániel Czuriga, Dániel Bereczki, Natan M. Bornstein, László Csiba
Dátum:2013
ISSN:1747-4930 1747-4949
Megjegyzések:Silent brain infarction (SBI) is a cerebral ischemic event evident on brain imaging without any clinical symptom. SBI is often detected in apparently healthy, elderly people and in different selected patient groups as well. Lately, several studies were carried out in order to identify the clinical conditions leading to SBI. A large number of clinical and paraclinical parameters were found to increase SBI prevalence, and the continuously growing list of risk factors revealed, that the majority of them are similar to those related to stroke. Accordingly, some consider SBI the preclinical stage of clinically overt stroke. This point of view emphasizes the early recognition and management of SBI related risk factors, and a great need for comparative studies, which could elicit the most sensitive indicators of the increased SBI risk, especially the ones that could be cost-effectively screened in the large populations as well.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Silent brain infarction
Cerebral ischemia
Stroke
Risk factors
Megjelenés:International Journal of Stroke. - 8 : 5 (2013), p. 334-347. -
További szerzők:Czuriga Dániel (1982-) (kardiológus) Bereczki Dániel (1960-) (neurológus) Bornstein, Natan M. Csiba László (1952-) (neurológus, pszichiáter)
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10.

001-es BibID:BIBFORM062617
Első szerző:Fekete Klára (neurológus)
Cím:Predictors of Long-term Outcome after Intravenous or Intra-arterial Recombinant Tissue Plasminogen Activator Treatment in the Eastern Hungarian Thrombolysis Database / Klára Fekete, Sándor Márton, Judit Tóth, László Csiba, István Fekete, Dániel Bereczki
Dátum:2015
ISSN:1052-3057 1532-8511
Megjegyzések:Background: This prospective single-center study aimed to identify features determininglong-term outcome after thrombolysis in a Central European stroke population.Methods: Between 1 January, 2004, and 31 December, 2010, 415 patients weretreated with recombinant tissue plasminogen activator at the Department ofNeurology, University of Debrecen. Stroke severity by the National Institute ofHealth Stroke Scale score (NIHSSS) and imaging findings by the Alberta Stroke ProgrammeEarly Computed Tomography score (ASPECTS) were evaluated on admissionand 1 day later. The modified Rankin Scale (mRS) at 3 months and case fatalityat 1 year were evaluated. Independent predictors of outcome were identified bymultivariate testing. Results: Data of 369 patients were analyzed. Median NIHSSSwas 12 (interquartile range [IQR], 8-17) on admission and 10 (IQR, 5-16) at 24 hours.Arterial occlusion was found in 55%. Symptomatic intracerebral hemorrhage (SICH)was detected in 3.8%. Outcome was significantly worse, and SICH was morefrequent in intra-arterially treated patients. At 3 months, one third of the patientswere independent (mRS #2), and 23% were dead. At 1 year 2 of 3 patients were alive.Significant independent predictors of disability at 3 months were 24-hour NIHSSS,admission ASPECTS, admission glucose level, and treatment modality. Only the24-hour NIHSSS was a significant predictor of case fatality at 1 year. Conclusions:Although short-term outcome was similar, the 3-month and 1-year outcomes wereworse than data from previous reports. A more efficient health care program shouldbe implemented after stroke to maintain the favorable effect of thrombolysis in thelong term.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Ischemic stroke
thrombolysis
predictors
outcome
Megjelenés:Journal Of Stroke And Cerebrovascular Diseases. - 24 : 1 (2015), p. 117-124. -
További szerzők:Márton Sándor (szociológus) Tóth Judit Csiba László (1952-) (neurológus, pszichiáter) Fekete István (1951-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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11.

001-es BibID:BIBFORM049525
Első szerző:Fekete Klára (neurológus)
Cím:Prestroke Alcohol Consumption and Smoking Are Not Associated with Stroke Severity, Disability at Discharge, and Case Fatality / Klára Fekete, Szabolcs Szatmári, Ildikó Szőcs, Csilla Szekeres, József Szász, László Mihálka, Volodymyr Smolanka, László Kardos, László Csiba, Dániel Bereczki
Dátum:2014
Megjegyzések:Background: Heavy alcohol consumption and smoking are known risk factors for stroke but their influence on stroke severity and outcome may also be important. We tested if alcohol consumption and smoking relate to initial stroke severity, disability at discharge from hospital and outcome at 30 days and at 1 year in 1049 patients of the Mures-Uzhgorod-Debrecen database. Methods: Initial stroke severity was scored by the NIH stroke scale. Case fatality and the modified outcome scale of the 1st International Stroke Trial were used to assess outcome. We used multiple regression analysis.Results: Before their stroke, 24.5% were smokers and 24.7 % admitted regular alcohol consumption. Neither smoking nor alcohol consumption status were associated with initial stroke severity. Case fatality at discharge, at 30 days and at 1 year were 12.2%, 16.9% and 28.3%, respectively. Initial stroke severity, hemorrhagic subtype, and age in men over 60 years were strong predictors of outcome. We did not find significant difference among alcohol consumers and non-consumers in 30-day and in one year case fatality in all stroke patients and in ischemic stroke patients. In hemorrhagic stroke, there was a non-significant tendency for higher case fatality among alcohol-consumers (39.5% vs. 26.4%, p>0.2 at 30 days and 48.8% vs. 35.8%, p>0.2 at 1 year). Smoking did not influence significantly the outcome at 30-days and at one-year.Conclusion: despite being risk factors, pre-stroke smoking and alcohol consumption do not have a significant influence on stroke severity and on short- and long- term outcome.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Alcohol, smoking and stroke severity
Megjelenés:Journal of Stroke and Cerebrovascular Diseases. - 23 : 1 (2014), p. e31-e37. -
További szerzők:Szatmári Szabolcs (1960-) (neurológus) Szőcs Ildikó (1970-) (orvos) Szekeres Csilla Cecília (1980-) (orvos) Szász József (1960-) (neurológus) Mihálka László (1950-) (neurológus) Smolanka, Volodymyr I. (1950-) (orvos) Kardos László (1970-) (megelőző orvostan és népegészségtan szakorvos) Csiba László (1952-) (neurológus, pszichiáter) Bereczki Dániel (1960-) (neurológus)
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12.

001-es BibID:BIBFORM045987
Első szerző:Gregson, Barbara A.
Cím:International Variations in Surgical Practice for Spontaneous Intracerebral Hemorrhage / Barbara A. Gregson, A. David Mendelow, STICH Investigators
Dátum:2003
ISSN:0039-2499 1524-4628
Megjegyzések:Background and Purpose -Spontaneous intracerebral hemorrhage is a major cause of death and disability, yet there is no convincing evidence of the benefit of any medical treatment and the role of surgery remains controversial. The international randomized Surgical Trial in Intracerebral Hemorrhage (STICH) provided an opportunity to assess the role of surgery within the centers taking part. Methods -Screening logs were completed to record details of all patients assessed by the department, whether they were included in the trial, the reasons if they were not included, and whether they underwent surgery. Results -Logs were returned by 42 centers and cover 704 months. They include details on 1578 patients with characteristics comparable to STICH inclusion criteria. Neurosurgeons were more likely to express clinical certainty about treatment for older patients, patients with a higher Glasgow Coma Score scale, and patients in whom the hematoma was located on the right or in the basal ganglia or thalamus. Patients for whom the neurosurgeon was certain about treatment were more likely to have the hematoma removed if they were younger (62 versus 68 years of age), had a lower Glasgow Coma Scale score (10 versus 13), and had a lobar hematoma (49% versus 40%). The operation rate varied between 74% in Lithuania and 2% in Hungary. Conclusions -The difference in operation rates could not be explained by differences in patient characteristics alone. This finding demonstrates the need for further evidence to ensure that treatment for intracerebral hemorrhage is not governed by local custom. ( Stroke . 2003;34:2593-2598.)
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
intracranial hemorrhages
multicenter studies
physician's practice patterns
surgery
Megjelenés:Stroke. - 34 : 11 (2003), p. 2593-2598. -
További szerzők:Mendelow, A. David Szabó Sándor (1957-) (idegsebész) Bereczki Dániel (1960-) (neurológus) STICH Investigators
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