Találati lista | Tudóstér

001-es BibID:	BIBFORM089626
Első szerző:	Köbling Tamás (belgyógyász)
Cím:	Predictors of dietary self-efficacy in high glycosylated hemoglobin A1c type 2 diabetic patients / Köbling Tamás, Váradi Zita, Katona Éva, Somodi Sándor, Kempler Péter, Páll Dénes, Zrínyi Miklós
Dátum:	2020
ISSN:	0300-0605
Megjegyzések:	Objective To predict dietary self-efficacy behaviors in high glycosylated hemoglobin A1c (HbA1c) patients using type D personality (TDP) and other psychosocial measures. Methods A cross-sectional, predictive research design was implemented. Participants were type 2 diabetes mellitus patients diagnosed more than 2 years prior to the study. Data were collected for demographics, dietary self-efficacy and psychological measures. Spearman's rank-order correlation was used to test for relationships, the Mann-Whitney test was used to test for differences and multiple linear regression was used to examine predictors of dietary self-efficacy. Results Lower dietary self-efficacy was strongly correlated with greater social isolation (r?=?0.93) and moderately correlated with more mental health problems (r?=?0.20) and higher TDP scores (r?=?0.17). Higher HbA1c was inversely related to self-reported physical health (r?=??0.19). Social and emotional isolation and time since diagnosis predicted dietary self-efficacy (greater isolation was associated with more dietary management difficulties). Conclusions Regression outcomes suggested that a 10% decrease in social isolation improves dietary self-efficacy by 30%, a significant boost to therapeutic adherence. We recommend assessment of social isolation to improve dietary self-efficacy and achieve better patient adherence to therapy.
Tárgyszavak:	Orvostudományok Egészségtudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Dietary self-efficacy glycosylated hemoglobin A1c diabetes type D personality social isolation emotional isolation mental health
Megjelenés:	Journal Of International Medical Research. - 48 : 6 (2020), p. 1-12. -
További szerzők:	Váradi Zita Katona Éva (1967-) (belgyógyász, diabetológus) Somodi Sándor (1977-) (belgyógyász) Kempler Péter (1954-) (belgyógyász, diabetológus) Páll Dénes (1967-) (belgyógyász, kardiológus) Zrínyi Miklós (1969-) (közgazdász)
Pályázati támogatás:	NKFIH1150-6/2019 NKFIH GINOP-2.3.2-15-2016-00062 GINOP
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:

001-es BibID:	BIBFORM094676
Első szerző:	Nádró Bíborka (általános orvos)
Cím:	Effects of alpha-lipoic acid treatment on serum progranulin levels and inflammatory markers in diabetic neuropathy / Bíborka Nádró, Hajnalka Lőrincz, Ágnes Molnár, Anita Szentpéteri, Eszter Zöld, Ildikó Seres, Dénes Páll, György Paragh, Péter Kempler, Mariann Harangi, Ferenc Sztanek
Dátum:	2021
ISSN:	0300-0605
Megjegyzések:	Objectives: Progranulin (PGRN) is a secreted growth factor that helps to regulate neuronal survival by blocking tumor necrosis factor-alpha (TNFa) receptors. The antioxidant alpha-lipoic acid (ALA) is used in diabetic neuropathy to improve nerve conduction and relieve neuropathic pain, but its effects on PGRN levels have not yet been elucidated. Methods: In this prospective study, 54 patients with type 2 diabetes and peripheral neuropathy received 600 mg of ALA daily for 6 months. Twenty-four patients with diabetes without neuropathy were also included in the study. Serum PGRN and TNFa levels were determined using enzyme-linked immunosorbent assays. In addition, current perception threshold (CPT) testing was used to assess sensory neuropathy. Results: After ALA treatment, serum PGRN levels were significantly increased and CPT values were significantly improved. Furthermore, there were significant positive correlations among TNFa, ICAM-1, and PGRN levels both before and after ALA treatment. A significant negative correlation was observed between the improvements in CPT and the PGRN levels. Furthermore, ICAM-1 levels were an independent predictor of PGRN levels. Conclusions: Changes in serum PGRN levels indicate that ALA treatment may have beneficial effects on endothelial function and neuronal inflammation.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk diabetic neuropathy cardiac autonomic neuropathy progranulin intercellular adhesion molecule-1 alpha-lipoic acid tumor necrosis factor-alpha type 2 diabetes
Megjelenés:	Journal of International Medical Research. - 49 : 5 (2021), p. 1-13. -
További szerzők:	Lőrincz Hajnalka (1986-) (biológus) Molnár Ágnes (1972-) (gyógytornász) Szentpéteri Anita (1988-) (biológus) Zöld Eszter (1988-) (szemész) Seres Ildikó (1954-) (biokémikus) Páll Dénes (1967-) (belgyógyász, kardiológus) Paragh György (1953-) (belgyógyász) Kempler Péter (1954-) (belgyógyász, diabetológus) Harangi Mariann (1974-) (belgyógyász, endokrinológus) Sztanek Ferenc (1982-) (orvos)
Pályázati támogatás:	EFOP-3.6.2-16-2017-00009 EFOP OTKA-115723 OTKA
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon: