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001-es BibID:	BIBFORM114949
035-os BibID:	(cikkazonosító)1095 (WoS)001080712600001 (Scopus)85172229294
Első szerző:	Csernátony Zoltán (ortopéd sebész, traumatológus)
Cím:	Acetabular Revision with McMinn Cup : Development and Application of a Patient-Specific Targeting Device / Csernátony Zoltán, Manó Sándor, Szabó Dániel, Soósné Horváth Hajnalka, Kovács Ágnes Éva, Csámer Loránd
Dátum:	2023
ISSN:	2306-5354
Megjegyzések:	Background: Surgeries of severe periacetabular bone defects (Paprosky ? 2B) are a major challenge in current practice. Although solutions are available for this serious clinical problem, they all have their disadvantages as well as their advantages. An alternative method of reconstructing such extensive defects was the use of a cup with a stem to solve these revision situations. As the instrumentation offered is typically designed for scenarios where a significant bone defect is not present, our unique technique has been developed for implantation in cases where reference points are missing. Our hypothesis was that a targeting device designed based on the CT scan of a patient's pelvis could facilitate the safe insertion of the guiding wire. Methods: Briefly, our surgical solution consists of a two-step operation. If periacetabular bone loss was found to be more significant during revision surgery, all implants were removed, and two titanium marker screws in the anterior iliac crest were percutaneously inserted. Next, by applying the metal artifact removal (MAR) algorithm, a CT scan of the pelvis was performed. Based on that, the dimensions and positioning of the cup to be inserted were determined, and a patient-specific 3D printed targeting device made of biocompatible material was created to safely insert the guidewire, which is essential to the implantation process. Results: In this study, medical, engineering, and technical tasks related to the design, the surgical technique, and experiences from 17 surgical cases between February 2018 and July 2021 are reported. There were no surgical complications in any cases. The implant had to be removed due to septic reasons (independently from the technique) in a single case, consistent with the septic statistics for this type of surgery. There was not any perforation of the linea terminalis of the pelvis due to the guiding method. The wound healing of patients was uneventful, and the implant was fixed securely. Following rehabilitation, the joints were able to bear weight again. After one to four years of follow-up, the patient satisfaction level was high, and the gait function of the patients improved a lot in all cases. Conclusions: Our results show that CT-based virtual surgical planning and, based on it, the use of a patient-specific 3D printed aiming device is a reliable method for major hip surgeries with significant bone loss. This technique has also made it possible to perform these operations with minimal X-ray exposure.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk stemmed cup hip revision surgery patient-specific instrumentation
Megjelenés:	Bioengineering-Basel. - 10 : 9 (2023), p. 1-13. -
További szerzők:	Manó Sándor (1977-) (gépészmérnök, számítógépes tervezőmérnök) Szabó Dániel (1988-) (ortopéd sebész, traumatológus) Soósné Horváth Hajnalka (1982-) (mérnök) Kovács Ágnes Éva (1993-) (mérnök) Csámer Lóránd (1983-) (mérnök)
Pályázati támogatás:	GINOP-2.3.2-15-2016-00022 GINOP GINOP-2.2.1-15-2017-00055 GINOP
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001-es BibID:	BIBFORM112171
035-os BibID:	(cikkazonosító)3861 (WoS)000997603500001 (Scopus)85160404373
Első szerző:	Kovács Ágnes Éva (mérnök)
Cím:	Comparative Analysis of Bone Ingrowth in 3D-Printed Titanium Lattice Structures with Different Patterns / Ágnes Éva Kovács, Zoltán Csernátony, Loránd Csámer, Gábor Méhes, Dániel Szabó, Mihály Veres, Mihály Braun, Balázs Harangi, Norbert Serbán, Lei Zhang, György Falk, Hajnalka Soósné Horváth, Sándor Manó
Dátum:	2023
ISSN:	1996-1944
Megjegyzések:	In this study, metal 3D printing technology was used to create lattice-shaped test specimens of orthopedic implants to determine the effect of different lattice shapes on bone ingrowth. Six different lattice shapes were used: gyroid, cube, cylinder, tetrahedron, double pyramid, and Voronoi. The lattice-structured implants were produced from Ti6Al4V alloy using direct metal laser sintering 3D printing technology with an EOS M290 printer. The implants were implanted into the femoral condyles of sheep, and the animals were euthanized 8 and 12 weeks after surgery. To determine the degree of bone ingrowth for different lattice-shaped implants, mechanical, histological, and image processing tests on ground samples and optical microscopic images were performed. In the mechanical test, the force required to compress the different lattice-shaped implants and the force required for a solid implant were compared, and significant differences were found in several instances. Statistically evaluating the results of our image processing algorithm, it was found that the digitally segmented areas clearly consisted of ingrown bone tissue; this finding is also supported by the results of classical histological processing. Our main goal was realized, so the bone ingrowth efficiencies of the six lattice shapes were ranked. It was found that the gyroid, double pyramid, and cube-shaped lattice implants had the highest degree of bone tissue growth per unit time. This ranking of the three lattice shapes remained the same at both 8 and 12 weeks after euthanasia. In accordance with the study, as a side project, a new image processing algorithm was developed that proved suitable for determining the degree of bone ingrowth in lattice implants from optical microscopic images. Along with the cube lattice shape, whose high bone ingrowth values have been previously reported in many studies, it was found that the gyroid and double pyramid lattice shapes produced similarly good results.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Materials. - 16 : 10 (2023), p. 1-16. -
További szerzők:	Csernátony Zoltán (1959-2023) (ortopéd sebész, traumatológus) Csámer Lóránd (1983-) (mérnök) Méhes Gábor (1966-) (patológus) Szabó Dániel (1988-) (ortopéd sebész, traumatológus) Veres Mihály (fizikus) Braun Mihály (1966-) (vegyész, analitikus) Harangi Balázs (1986-) (programtervező matematikus) Serban Norbert Zhang, Lei (1988-) (orvos) Falk György Soósné Horváth Hajnalka (1982-) (mérnök) Manó Sándor (1977-) (gépészmérnök, számítógépes tervezőmérnök)
Pályázati támogatás:	GINOP-2.2.1-15-2017-00055 GINOP PD 137775 Egyéb
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001-es BibID:	BIBFORM110779
Első szerző:	Kovács Ágnes Éva (mérnök)
Cím:	Csípőízületi vápadefektus-klasszifikáció megjelenítése 3D nyomtatással készült modellek segítségével / Kovács Ágnes Éva, Csernátony Zoltán, Szabó Dániel, Csámer Loránd, Somoskeöy Szabolcs, Manó Sándor
Dátum:	2022
Tárgyszavak:	Orvostudományok Klinikai orvostudományok magyar nyelvű folyóiratközlemény hazai lapban folyóiratcikk
Megjelenés:	Biomechanika Hungarica. - 15 : 2 (2022), p. 43-48. -
További szerzők:	Csernátony Zoltán (1959-2023) (ortopéd sebész, traumatológus) Szabó Dániel (1988-) (ortopéd sebész, traumatológus) Csámer Lóránd (1983-) (mérnök) Somoskeöy Szabolcs Manó Sándor (1977-) (gépészmérnök, számítógépes tervezőmérnök)
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