Találati lista | Tudóstér

001-es BibID:	BIBFORM087717
Első szerző:	Buglyó Péter (vegyész)
Cím:	Speciation and NMR relaxation studies of VO(IV) complexes with several O-donor containing ligands: oxalate, malonate, maltolate and kojate / Péter Buglyó, Erzsébet Kiss, István Fábián, Tamás Kiss, Daniele Sanna, Eugenio Garribba, Giovanni Micera
Dátum:	2000
ISSN:	0020-1693
Megjegyzések:	Potentiometric, spectral and 1H NMR relaxation studies are reported on the complex formation of VO(IV) with the bidentate chelating ligands oxalic and malonic acids, of a dicarboxylic nature, and maltol and kojic acid, of the hydroxy-4-pyrone type. Complexes with stochiometries VOA and VOA2 were characterised in aqueous solution. Two main features were established for the complex systems. It was found that five-membered ring chelation favours the cis arrangement in the bis complexes of maltol and kojic acid to a higher extent than in those of oxalic and malonic acids. Moreover, previous investigations of VO(IV) binding to maltol or its analogues did not consider the formation of hydroxo species. Formation of dihydroxo bridged dimeric complexes of stoichiometry (VOAH?1)2 and monomeric hydroxo species VOA2H?1 or VOA2(OH), are now taken into account in order to explain the equilibrium and spectroscopic results. 1H NMR relaxation measurements strongly suggest an equilibrium between the two isomers of the bis complexes.
Tárgyszavak:	Természettudományok Kémiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk Vanadium complexes Oxo complexes Oxalate complexes Malonate complexes Maltolate complexes
Megjelenés:	Inorganica Chimica Acta. - 306 : 2 (2000), p. 174-183. -
További szerzők:	Kiss Erzsébet (vegyész) Fábián István (1956-) (vegyész) Kiss Tamás Sanna, Daniele (1956-) (vegyész) Garribba, Eugenio Micera, Giovanni
Pályázati támogatás:	T 23776 OTKA T 29568 OTKA T 28244 OTKA FKFP 0013/97 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:

001-es BibID:	BIBFORM086035
Első szerző:	Buglyó Péter (vegyész)
Cím:	Interaction between the low molecular mass components of blood serum and the VO(iv)-DHP system (DHP = 1,2-dimethyl-3-hydroxy-4(1H)-pyridinone) / Péter Buglyó, Tamás Kiss, Erzsébet Kiss, Daniele Sanna, Eugenio Garribba, Giovanni Micera
Dátum:	2002
ISSN:	0300-9246 1364-5447
Megjegyzések:	In order to estimate the impact of the low molecular mass (l.m.m.) VO(IV) binders of blood serum on the potentially insulin-enhancing drug [VO(DHP)(2)] [DHP=1,2-dimethyl-3-hydroxy-4(1H)-pyridinone], the speciation in the binary system VO(IV)-DHP and in the ternary systems VO-DHP-ligand B (B=oxalate, lactate, citrate or phosphate) was studied by pH-potentiometry at 25.0degreesC and at an ionic strength I=0.2 mol dm(-3) (KCl). The binding modes of the complexes formed were determined by spectroscopic (electronic absorption and EPR) techniques. DHP was found to form stable mono and bis complexes via the coordination of (O,O) chelate(s). Through displacement of the oxo group of VO(), the tris complex is also formed, especially at a high excess of ligand. The results in the ternary systems demonstrate that, at physiological pH, none of the B ligands can compete with DHP; [VO(DHP)(2)] therefore seems to remain almost completely intact, even in the presence of citrate, the strongest competitor among these B ligands. These findings indicate that, for DHP, unlike maltol or picolinic acid, ternary complex formation and thus transformation reactions with the l.m.m. binders of biofluids, is almost negligible. From among the three carrier molecules, only DHP can efficiently compete with serum transferrin for binding of VO(IV).
Tárgyszavak:	Természettudományok Kémiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk
Megjelenés:	Journal of the Chemical Society. Dalton Transactions. - 11 (2002), p. 2275-2282. -
További szerzők:	Kiss Tamás (1950-) (vegyész) Kiss Erzsébet (vegyész) Sanna, Daniele (1956-) (vegyész) Garribba, Eugenio Micera, Giovanni
Pályázati támogatás:	T31896 OTKA F32235 OTKA
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:

001-es BibID:	BIBFORM085988
Első szerző:	Pessoa, Joăo Costa
Cím:	The systems VIVO2+-glutathione and related ligands: a potentiometric and spectroscopic study / João Costa Pessoa, Isabel Tomaz, Tamás Kiss, Erzsébet Kiss, Péter Buglyó
Dátum:	2002
ISSN:	0949-8257
Megjegyzések:	The equilibria in the system (VO2+)-O-IV-glutathione in aqueous solution were studied in the pH range 2-11 by a combination of pH-potentiometry, and spectroscopy (EPR, visible absorption and circular dichroism). The results of the various methods are consistent and the equilibrium model includes the species MLH3, MLH2, MLH, ML2H2, MLH-1, and MLH-2 and several hydrolysis products (where H4L denotes totally protonated glutathione); individual formation constants and spectra are given. ML2H2 is the predominant species at physiological pH. Plausible structures for each stoichiometry are discussed. The related (VO2+)-O-IV systems of S-methylglutathione and gamma-L-glutamyl-L-cysteinyl ethyl ester were studied by means of the same spectroscopic techniques in order to support the established binding modes for the glutathione complexes. The importance of glutathione and oxidized glutathione in binding (VO2+)-O-IV in cells is assessed.
Tárgyszavak:	Természettudományok Kémiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk vanadium glutathione potentiometry spectroscopy coordination modes
Megjelenés:	Journal of Biological Inorganic Chemistry. - 7 : 3 (2002), p. 225-240. -
További szerzők:	Tomaz, Isabel Kiss Tamás (1950-) (vegyész) Kiss Erzsébet (vegyész) Buglyó Péter (1965-) (vegyész)
Pályázati támogatás:	FKFP 0013/97 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon: