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001-es BibID:	BIBFORM068043
Első szerző:	Erdődi Balázs (szülész-nőgyógyász szakorvosjelölt)
Cím:	Prognostic imaging and laboratory properties of cystic ovarian structures in the peri- and postmenopause / Erdődi Balázs, Tóth Zoltán, Jakab Attila
Dátum:	2014
ISSN:	1369-7137
Megjegyzések:	Aim: To determine the efficacy of ultrasound (US) examinations and CA-125 measurement in the diagnosis of peri- and postmenopausal ovarian cysts. Materials and Methods: Imaging properties of peri- (PEM) and post-menopausal (POM) ovarian cysts were examined preoperatively. According to US findings two groups were made: (1) simple cysts: unilocular, anechoic cysts without papillarization, (2) complex cysts: cystic structures with different parameters. Imaging characteristics, size were matched with histology and CA125 levels. Results: 379 cystic structures (PEM: N 195, average age: 45.6 yrs; range: 40 ? 54 yrs, POM: N 184, average age 61.2 yrs; range: 41 ? 88 yrs) were analysed. In the PEM group 75 simple ( ? 5cm N32, ? 5cm N43) and 122 complex cysts ( ? 5 cm N 29, ? 5 cm, N 93), while in the POM group 49 simple (? 5 cm N 9, ? 5 cm N 40) and 135 complex cysts (? 5 cm N 15, ? 5 cm N 120) were found. In the PEM group malignancy was detected in complex cysts larger than 5cm (N 16, 17.58%). In the POM group we found malignancy in 40 cases, three of them smaller than 5cm. Majority of cysts were functional (54.36 %) in the PEM group. In the POM group serous cysts were the most frequent (38.04%), followed by malignant (21.74%) and mucinous cysts (13.04%). CA125 were elevated in 66 of 217 cases (30.41%), only 23 of these were malignant (NPV: 0.95, PPV: 0.35). Discussion: Functional cysts are frequently found among perimenopausal ovarian cysts, but we detected malignancy only among complex cysts larger than 5 cms. However, complex cyst of any size carrysignifi cant risk of malignancy in the menopause, thus surgery isrecommended. Simple cysts can be followed by serial scan in both groups. CA-125 did not give added value to the detection of malignancy.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idézhető absztrakt Ovary Ultrasonography CA125
Megjelenés:	Climacteric 17 : Sup. 1 (2014), p. 24. -
További szerzők:	Tóth Zoltán (1948-) (szülész-nőgyógyász, humángenetikus) Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus)
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
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