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001-es BibID:BIBFORM112576
035-os BibID:(WoS)000785165700001 (Scopus)85127768738
Első szerző:Győri Enikő (vegyész)
Cím:Environment-Friendly Catalytic Mineralization of Phenol and Chlorophenols with Cu- and Fe- Tetrakis(4-aminophenyl)-porphyrin-Silica Hybrid Aerogels / Enikő Győri, Ádám Kecskeméti, István Fábián, Máté Szarka, István Lázár
Dátum:2022
ISSN:2310-2861
Megjegyzések:Fenton reactions with metal complexes of substituted porphyrins and hydrogen peroxide are useful tools for the mineralization of environmentally dangerous substances. In the homogeneous phase, autooxidation of the prophyrin ring may also occur. Covalent binding of porphyrins to a solid support may increase the lifetime of the catalysts and might change its activity. In this study, highly water-insoluble copper and iron complexes of 5,10,15,20-tetrakis(4- minophenyl)porphyrin were synthesized and bonded covalently to a very hydrophilic silica aerogel matrix prepared by co-gelation of the propyl triethoxysilyl-functionalized porphyrin complex precursors with tetramethoxysilane, followed by a supercritical carbon dioxide drying. In contrast to the insoluble nature of the porphyrin complexes, the as-prepared aerogel catalysts were highly compatible with the aqueous phase. Their catalytic activities were tested in the mineralization reaction of phenol, 3-chlorophenol, and 2,4-dichlorophenol with hydrogen peroxide. The results show that both aerogels catalyzed the oxidation of phenol and chlorophenols to harmless short-chained carboxylic acids under neutral conditions. In batch experiments, and also in a miniature continuous-flow tubular reactor, the aerogel catalysts gradually reduced their activity, due to the slow oxidation of the porphyrin ring. However, the rate and extent of the degradation was moderate and did not exclude the possibility that the as-prepared catalysts, as well as their more stable derivatives, might find practical applications in environment protection.
Tárgyszavak:Természettudományok Kémiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
silica aerogel
aerogel hybrid
covalent immobilization
porphyrin complexes
heterogeneous catalyst
phenol mineralization
chlorophenol mineralization
Megjelenés:Gels. - 8 : 4 (2022), p. 202-. -
További szerzők:Kecskeméti Ádám (1992-) (vegyész) Fábián István (1956-) (vegyész) Szarka Máté (1990-) Lázár István (1959-) (vegyész)
Pályázati támogatás:GINOP-2.3.2-15-2016-00041
GINOP
GINOP-2.2.1-15-2017-00068
GINOP
GINOP-2.3.2- 15-2016-00008
GINOP
GINOP-2.3.3-15-2016-00004
GINOP
17-124983
OTKA
K127931
Egyéb
GINOP-2.3.3-15-2016-00029
GINOP
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2.

001-es BibID:BIBFORM116370
035-os BibID:(cikkazonosító)812 (Scopus)85175438968 (WoS)001097903200001
Első szerző:Lázár István (vegyész)
Cím:Editorial for the Special Issue: "Aerogel Hybrids and Nanocomposites" / István Lázár, Melita Menelaou
Dátum:2023
ISSN:2310-2861
Tárgyszavak:Természettudományok Kémiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Gels. - 9 : 10 (2023), p. 1-4. -
További szerzők:Menelaou, Melita
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3.

001-es BibID:BIBFORM115041
035-os BibID:(cikkazonosító)746 (Scopus)85172198835 (WoS)001071759300001
Első szerző:Lázár István (vegyész)
Cím:Aercogel-Based Materials in Bone and Cartilage Tissue Engineering : A Review with Future Implications / Lázár, István; Čelko, Ladislav; Menelaou, Melita
Dátum:2023
ISSN:2310-2861
Megjegyzések:: Aerogels are fascinating solid materials known for their highly porous nanostructure and exceptional physical, chemical, and mechanical properties. They show great promise in various technological and biomedical applications, including tissue engineering, and bone and cartilage substitution. To evaluate the bioactivity of bone substitutes, researchers typically conduct in vitro tests using simulated body fluids and specific cell lines, while in vivo testing involves the study of materials in different animal species. In this context, our primary focus is to investigate the applications of different types of aerogels, considering their specific materials, microstructure, and porosity in the field of bone and cartilage tissue engineering. From clinically approved materials to experimental aerogels, we present a comprehensive list and summary of various aerogel building blocks and their biological activities. Additionally, we explore how the complexity of aerogel scaffolds influences their in vivo performance, ranging from simple single-component or hybrid aerogels to more intricate and organized structures. We also discuss commonly used formulation and drying methods in aerogel chemistry, including molding, freeze casting, supercritical foaming, freeze drying, subcritical, and supercritical drying techniques. These techniques play a crucial role in shaping aerogels for specific applications. Alongside the progress made, we acknowledge the challenges ahead and assess the near and far future of aerogel-based hard tissue engineering materials, as well as their potential connection with emerging healing techniques.
Tárgyszavak:Természettudományok Kémiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
aerogel
tissue engineering
artificial bone substitution
in vitro and in vivo bioactivity
biodegradation
cartilage regeneration
scaffold
osteogenesis
simulated body fluids
mmortalized cell lines
Megjelenés:Gels. - 9 : 9 (2023), p. 1-40. -
További szerzők:Čelko, Ladislav Menelaou, Melita
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4.

001-es BibID:BIBFORM096825
035-os BibID:(cikkazonosító)55
Első szerző:Lázár István (vegyész)
Cím:Prevention of the Aggregation of Nanoparticles during the Synthesis of Nanogold-Containing Silica Aerogels / Lázár István, Szabó Hanna Judit
Dátum:2018
ISSN:2310-2861
Tárgyszavak:Természettudományok Kémiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Gels. - 4 : 2 (2018), p. 1-9. -
További szerzők:Szabó Hanna Judit (1996-) (vegyészmérnök)
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5.

001-es BibID:BIBFORM081372
035-os BibID:(cikkazonosító)26
Első szerző:Lázár István (vegyész)
Cím:A Continuous Extraction and Pumpless Supercritical CO2 Drying System for Laboratory-Scale Aerogel Production / István Lázár, István Fábián
Dátum:2016
ISSN:2310-2861
Megjegyzések:Production of aerogels starts with solution chemistry and may end with supercritical carbon dioxide drying, which both require a specialized system. Here we present a complete aerogel production system that was developed and used in our laboratory over the last nine years. Our aim was to develop a supercritical dryer and a protocol, whereby the CO2 pump can be left out, and the entire flow system is operated by the pressure of the CO2 cylinder. Drying pressure and temperature are controlled by the combination of the filling and heating temperatures. A continuous-mode solvent exchange system has also been developed, in which the solvent consumption during the process can be reduced to one-third of the batch method. In the new medium temperature 1.5 L volume supercritical dryer, the temperature is set to a constant 80-82 °C, and the pressure can be in the 90-200 bar range, depending on the conditions. We have performed approximately 200 dryings thus far, and prepared a wide range of monolithic aerogels, from pristine silica aerogels to polysaccharides and collagen. In this paper, we have summarized not only the technical details, but also the work experiences, as well as advantages and disadvantages of the systems.
Tárgyszavak:Természettudományok Kémiai tudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
aerogel production
supercritical CO2 drying
continuous solvent extraction
liquid CO2 extraction
medium temperature process
Megjelenés:Gels. - 2 : 4 (2016), p. 1-15. -
További szerzők:Fábián István (1956-) (vegyész)
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