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001-es BibID:	BIBFORM034875
Első szerző:	Ebel, H.
Cím:	Effects of Electrical Stimulation of theGasserian Ganglion on Regional Cerebral Blood Flow after Induced Subarachnoid Hemorrhage in Pigs Evaluated by 99mTc-HMPAO-SPECT / Ebel H., Semmelmann G., Friese M., Volz M., Lee J. Y., Dück M., Schomäcker K., Varga J., Furka I., Schröder R., Klug N.
Dátum:	2001
ISSN:	0946-7211
Megjegyzések:	It could be demonstrated that cervical spinal cord stimulation increases cerebral blood flow. The effects of electrical stimulation of the trigeminal ganglion in the acute phase of SAH in pigs were investigated. The experiments were carried out on 11 domestic pigs divided in two groups (group I: SAH [n = 5]; group II: SAH and trigeminal stimulation [n = 6]). In all animals a native SPECT was performed. The Gasserian ganglion was exposed for inserting the stimulation electrode. SAH was induced by injecting 10 ml autologous blood through a catheter placed in the suprasellar cistern. 30 minutes after SAH-induction electrical stimulation was started for two hours in group II (2.8-4.5 V, 50 Hz, 300 microseconds). 99mTc-HMPAO (400-540 MBq) was injected intravenously 110 minutes later. In group I 99mTc-HMPAO was applied after the same time interval. 80 minutes later SPECT was performed. Data were processed to calculate the uptake of radioactivity (%/kg tissue weight). The mean values were calculated for the different groups: native animal examination (%/kg tissue weight): 0.6343; group I: 0.468; group II: 0.6533. Comparing the mean values a highly significant difference between group I and group II (p < 0.01) and between native examination and group I (p < 0.01) could be found. No statistical significance could be detected on comparing the left/right-ratio in any ROI. The electrical stimulation of the Gasserian ganglion leads to a significantly increased uptake of 99mTc-HMPAO after induced SAH. Maybe the stimulation of the Gasserian ganglion constitutes a new therapeutic modality treating disturbed rCBF after SAH.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Minimally Invasive Neurosurgery. - 44 : 1 (2001), p. 50-57. -
További szerzők:	Semmelmann G. Friese, M. Volz, M. Lee, J. Y. Dück, M. Schomäcker, K. Varga József (1955-) (fizikus) Furka István (1935-2021) (sebész, urológus, kutatóorvos) Schröder, Roland Klug, Norfrid
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001-es BibID:	BIBFORM031206
Első szerző:	Rieger, Andreas
Cím:	Is it useful to measure supratentorial ICP in the presence of a posterior fossa lesion? Absence of transtentorial pressure gradients in an animal model / Rieger A., Rainov N. G., Sanchin L., Ebel H., Furka I., Görömbey Z., Burkert W.
Dátum:	1999
Megjegyzések:	Previous studies with animal models of supratentorial ICP elevation have demonstrated a pressure gradient between the supratentorial and the infratentorial compartments. The present study was designed to investigate the possible presence of such a gradient in the case of infratentorial ICP elevation. An inflatable infratentorial balloon catheter was implanted in seven domestic pigs. The infratentorial ICP (ICPi) was measured in the left cerebellar hemisphere, and the supratentorial ICP (ICPs) was measured in the left cerebral hemisphere. The corresponding pulse amplitudes (ICPi-PA, ICPs-PA) were recorded in both compartments, and the cerebral perfusion pressure (CPP) was calculated. ICPi and ICPs values prior to balloon inflation were 4.4 (SD 2.2) and 4.1 (SD 2.3) mm Hg, respectively, and increased to 63.1 (SD 32.6) and 62.3 (SD 28.1) mmHg after balloon inflation. ICPi-PA rose from 3.1 (SD 0.43) to 12.8 (SD 8.0) mmHg, and ICPs-PA rose from 3.2 (SD 0.63) to 13.0 (SD 7.1) mmHg. CPP decreased from 86.1 (SD 12.0) to 55.4 (SD 14.6) mm Hg. The paired difference between ICPi and ICPs values was 0.44 (SD 1.96) mmHg, and the paired difference of ICP amplitudes was 0.03 (SD 1.19) mmHg. All these differences in infratentorial and supratentorial values were statistically not significant. In conclusion, infratentorial ICP elevation in the presented pig model leads to a uniform ICP elevation in the intracranial space without development of a considerable pressure gradient below and above the tentorium. In the low pressure part of the ICP curve, cerebrospinal fluid connects the compartments and contributes to the pressure equilibrium. The early obstruction of the foramen magnum by intruding cerebellar tissue seems to isolate the infratentorial from the spinal compartment. In the high-pressure part of the curve, the upwards cerebellar transtentorial herniation takes over the pressure transfer, and the whole intracranial space can be considered as a single compartment in the pig.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	British Journal of Neurosurgery. - 13 : 5 (1999), p. 454-458. -
További szerzők:	Rainov, N. G. Sanchin, Lhagva Ebel, H. Furka István (1935-2021) (sebész, urológus, kutatóorvos) Görömbey Zoltán (1956-) (idegsebész) Burkert, Winfried
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:	bibEBI16681
Első szerző:	Rieger, Andreas
Cím:	Continuous monitoring of oxygen partial pressure in cerebral venous blood / Rieger, A., Menzel, M., Rainov, N., Sanchin, L., Roth, S., Görömbey, Z., Furka, I., Burkert, W.
Dátum:	1997
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Neurosurgery. - 41 (1997), p. 462-467. -
További szerzők:	Menzel, Matthias (sebész) Rainov, Nicolai Sanchin, Lhagva Roth, Stephan Görömbey Zoltán (1956-) (idegsebész) Furka István (1935-2021) (sebész, urológus, kutatóorvos) Burkert, Winfried
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