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1.

001-es BibID:BIBFORM063749
Első szerző:Márk László (belgyógyász, kardiológus)
Cím:Non-HDL cholesterol goal attainment and its relationship with triglyceride concentrations among diabetic subjects with cardiovascular disease : a nationwide survey of 2674 individuals in Hungary / Laszlo Mark, Antonio J. Vallejo-Vaz, Istvan Reiber, Gyorgy Paragh, Sreenivasa Rao Kondapally Seshasai, Kausik K. Ray
Dátum:2015
ISSN:0021-9150
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Atherosclerosis. - 241 : 1 (2015), p. 62-68. -
További szerzők:Vallejo-Vaz, Antonio J. Reiber István Paragh György (1953-) (belgyógyász) Kondapally Seshasai, S. R. Ray, Kausik K.
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2.

001-es BibID:BIBFORM062771
Első szerző:Vallejo-Vaz, Antonio J.
Cím:Relationship of non-HDL-cholesterol levels and goal attainment with triglycerides and remnant lipoproteins in a nationwide survey of over 2600 diabetic subjects with cardiovascular disease / A. J. Vallejo-Vaz, L. Mark, I. Reiber, G. Paragh, S. R. Kondapally Seshasai, K. K. Ray
Dátum:2015
ISSN:0021-9150
Tárgyszavak:Orvostudományok Egészségtudományok idézhető absztrakt
Megjelenés:Atherosclerosis 241 : 1 (2015), p. e58. -
További szerzők:Mark L. Reiber István Paragh György (1953-) (belgyógyász) Kondapally Seshasai, S. R. Ray, Kausik K.
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3.

001-es BibID:BIBFORM097971
Első szerző:EAS Familial Hypercholesterolaemia Studies Collaboration
Cím:Global perspective of familial hypercholesterolaemia : a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC) / EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
Dátum:2021
ISSN:0140-6736
Megjegyzések:Background The European Atherosclerosis Society Familial Hypercholesterolaemia Studies Collaboration (FHSC) global registry provides a platform for the global surveillance of familial hypercholesterolaemia through harmonisation and pooling of multinational data. In this study, we aimed to characterise the adult population with heterozygous familial hypercholesterolaemia and described how it is detected and managed globally. Methods Using FHSC global registry data, we did a cross-sectional assessment of adults (aged 18 years or older) with a clinical or genetic diagnosis of probable or definite heterozygous familial hypercholesterolaemia at the time they were entered into the registries. Data were assessed overall and by WHO regions, sex, and index versus non-index cases. Findings Of the 61 612 individuals in the registry, 42 167 adults (21 999 [53?6%] women) from 56 countries were included in the study. Of these, 31798 (75?4%) were diagnosed with the Dutch Lipid Clinic Network criteria, and 35 490 (84?2%) were from the WHO region of Europe. Median age of participants at entry in the registry was 46?2 years (IQR 34?3?58?0); median age at diagnosis of familial hypercholesterolaemia was 44?4 years (32?5?56?5), with 40?2% of participants younger than 40 years when diagnosed. Prevalence of cardiovascular risk factors increased progressively with age and varied by WHO region. Prevalence of coronary disease was 17?4% (2?1% for stroke and 5?2% for peripheral artery disease), increasing with concentrations of untreated LDL cholesterol, and was about two times lower in women than in men. Among patients receiving lipid-lowering medications, 16803 (81?1%) were receiving statins and 3691 (21?2%) were on combination therapy, with greater use of more potent lipid-lowering medication in men than in women. Median LDL cholesterol was 5?43 mmol/L (IQR 4?32?6?72) among patients not taking lipid-lowering medications and 4?23 mmol/L (3?20?5?66) among those taking them. Among patients taking lipid-lowering medications, 2?7% had LDL cholesterol lower than 1?8 mmol/L; the use of combination therapy, particularly with three drugs and with proprotein convertase subtilisin?kexin type 9 inhibitors, was associated with a higher proportion and greater odds of having LDL cholesterol lower than 1?8 mmol/L. Compared with index cases, patients who were non-index cases were younger, with lower LDL cholesterol and lower prevalence of cardiovascular risk factors and cardiovascular diseases (all p<0?001). Interpretation Familial hypercholesterolaemia is diagnosed late. Guideline-recommended LDL cholesterol concentrations are infrequently achieved with single-drug therapy. Cardiovascular risk factors and presence of coronary disease were lower among non-index cases, who were diagnosed earlier. Earlier detection and greater use of combination therapies are required to reduce the global burden of familial hypercholesterolaemia.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Pfizer
Amgen
Merck Sharp & Dohme
Sanofi-Aventis
Daiichi Sankyo
Regeneron
Megjelenés:Lancet. - 398 : 10312 (2021), p. 1713-1725. -
További szerzők:Paragh György (1953-) (belgyógyász) Harangi Mariann (1974-) (belgyógyász, endokrinológus) Vallejo-Vaz, Antonio J.
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4.

001-es BibID:BIBFORM075404
035-os BibID:(WoS)000445908000037 (Scopus)85053666909
Első szerző:EAS Familial Hypercholesterolaemia Studies Collaboration
Cím:Overview of the current status of familial hypercholesterolaemia care in over 60 countries : The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC) / EAS Familial Hypercholesterolaemia Studies Collaboration, Antonio J. Vallejo-Vaz, Martina De Marco, Christophe A. T. Stevens, Asif Akram, Tomas Freiberger, G. Kees Hovingh, John J. P. Kastelein, Pedro Mata, Frederick J. Raal, Raul D. Santos, Handrean Soran, Gerald F. Watts, Marianne Abifadel, Carlos A. Aguilar-Salinas, Mutaz Al-khnifsawi, Fahad A. AlKindi, Fahad Alnouri, Rodrigo Alonso, Khalid Al-Rasadi, Ahmad Al-Sarraf, Tester F. Ashavaid, Christoph J. Binder, Martin P. Bogsrud, Mafalda Bourbon, Eric Bruckert, Krzysztof Chlebus, Pablo Corral, Olivier Descamps, Ronen Durst, Marat Ezhov, Zlatko Fras, Jacques Genest, Urh Groselj, Mariko Harada-Shiba, Meral Kayikcioglu, Katarina Lalic, Carolyn S. P. Lam, Gustavs Latkovskis, Ulrich Laufs, Evangelos Liberopoulos, Jie Lin, Vincent Maher, Nelson Majano, A. David Marais, Winfried März, Erkin Mirrakhimov, André R. Miserez, Olena Mitchenko, Hapizah M. Nawawi, Børge G. Nordestgaard, György Paragh, Zaneta Petrulioniene, Belma Pojskic, Arman Postadzhiyan, Ashraf Reda, Željko Reiner, Wilson E. Sadoh, Amirhossein Sahebkar, Abdullah Shehab, Aleksander B. Shek, Mario Stoll, Ta-Chen Su, Tavintharan Subramaniam, Andrey V. Susekov, Phivos Symeonides, Myra Tilney, Brian Tomlinson, Thanh-Huong Truong, Alexandros D. Tselepis, Anne Tybjærg-Hansen, Alejandra Vázquez-Cárdenas, Margus Viigimaa, Branislav Vohnout, Elisabeth Widén, Shizuya Yamashita, Maciej Banach, Dan Gaita, Lixin Jiang, Lennart Nilsson, Lourdes E. Santos, Heribert Schunkert, Lale Tokgözoğlu, Josip Car, Alberico L. Catapano, Kausik K. Ray, EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC) Investigators
Dátum:2018
ISSN:0021-9150
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Megjelenés:Atherosclerosis. - 277 (2018), p. 234-255. -
További szerzők:Vallejo-Vaz, Antonio J. De Marco, Martina Stevens, Christophe A. T. Akram, Asif Freiberger, Tomas Hovingh, G. Kees Kastelein, John J. P. Mata, Pedro Raal, Frederick J. Santos, Raul D. Soran, Handrean Watts, Gerald F. Abifadel, Marianne Aguilar-Salinas, Carlos A. Al-khnifsawi, Mutaz AlKindi, Fahad A. Alnouri, Fahad Alonso, Rodrigo Al-Rasadi, Khalid Al-Sarraf, Ahmad Ashavaid, Tester F. Binder, Christoph J. Bogsrud, Martin P. Bourbon, Mafalda Bruckert, Eric Chlebus, Krzysztof Corral, Pablo Descamps, Olivier Durst, Ronen Ezhov, Marat V. Fras, Zlatko Genest, Jaques Groselj, Urh Harada-Shiba, Mariko Kayikcioglu, Meral Lalic, Katarina Lam, Carolyn S. P. Latkovskis, Gustavs Laufs, Ulrich Liberopoulos, Evangelos Lin, Jie Maher, Vincent Majano, Nelson Marais, A. David März, Winfried Mirrakhimov, Erkin Miserez, André R. Mitchenko, Olena Nawawi, Hapizah Nordestgaard, Børge G. Paragh György (1953-) (belgyógyász) Petrulioniene, Zaneta Pojskic, Belma Postadzhiyan, Arman Reda, Ashraf Reiner, Željko Sadoh, Wilson E. Sahebkar, Amirhossein Shehab, Abdullah Shek, Alexander B. Stoll, Mario Su, Ta-Chen Subramaniam, Tavintharan Susekov, Andrey Symeonides, Phivos Tilney, Myra Tomlinson, Brian Truong, Thanh-Huong Tselepis, Alexandros D. Tybjærg-Hansen, Anne Vázquez-Cárdenas, Alejandra Viigimaa, Margus Vohnout, Branislav Widén, Elisabeth Yamashita, Shizuya Banach, Maciej Gaita, Dan Jiang, Lixin Nilsson, Lennart Santos, Lourdes E. Schunkert, Heribert Tokgözoğlu, Lale Car, Josip Catapano, Alberico L. Ray, Kausik K.
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5.

001-es BibID:BIBFORM069504
Első szerző:The EAS Familial Hypercholesterolaemia Studies Collaboration
Cím:Pooling and expanding registries of familial hypercholesterolaemia to assess gaps in care and improve disease management and outcomes : rationale and design of the global EAS Familial Hypercholesterolaemia Studies Collaboration / The EAS Familial Hypercholesterolaemia Studies Collaboration, Vallejo-Vaz Antonio J., Akram Asif, Kondapally Seshasai Sreenivasa Rao, Cole Della, Watts Gerald F., Hovingh G. Kees, Kastelein John J. P., Mata Pedro, Raal Frederick J., Santos Raul D., Soran Handrean, Freiberger Tomas, Abifadel Marianne, Aguilar-Salinas Carlos A., Alnouri Fahad, Alonso Rodrigo, Al-Rasadi Khalid, Banach Maciej, Bogsrud Martin P., Bourbon Mafalda, Bruckert Eric, Car Josip, Ceska Richard, Corral Pablo, Descamps Olivier, Dieplinger Hans, Do Can T., Durst Ronen, Ezhov Marat V., Fras Zlatko, Gaita Dan, Gaspar Isabel M., Genest Jaques, Harada-Shiba Mariko, Jiang Lixin, Kayikcioglu Meral, Lam Carolyn S. P., Latkovskis Gustavs, Laufs Ulrich, Liberopoulos Evangelos, Lin Jie, Lin Nan, Maher Vincent, Majano Nelson, Marais A. David, März Winfried, Mirrakhimov Erkin, Miserez André R., Mitchenko Olena, Nawawi Hapizah, Nilsson Lennart, Nordestgaard Børge G., Paragh György, Petrulioniene Zaneta, Pojskic Belma, Reiner Ẑeljko, Sahebkar Amirhossein, Santos Lourdes E., Schunkert Heribert, Shehab Abdullah, Slimane M. Naceur, Stoll Mario, Su Ta-Chen, Susekov Andrey, Tilney Myra, Tomlinson Brian, Tselepis Alexandros D., Vohnout Branislav, Widén Elisabeth, Yamashita Shizuya, Catapano Alberico L., Ray Kausik K.
Dátum:2016
ISSN:1567-5688
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Familial hypercholesterolaemia
LDL-Cholesterol
Cardiovascular disease
Registry
Study design
Familial Hypercholesterolaemia Studies Collaboration
Megjelenés:Atherosclerosis Supplements. - 22 (2016), p. 1-32. -
További szerzők:Vallejo-Vaz, Antonio J. Akram, Asif Kondapally Seshasai, S. R. Cole, Della Watts, Gerald F. Hovingh, G. Kees Kastelein, John J. P. Mata, Pedro Raal, Frederick J. Santos, Raul D. Soran, Handrean Freiberger, Tomas Abifadel, Marianne Aguilar-Salinas, Carlos A. Alnouri, Fahad Alonso, Rodrigo Al-Rasadi, Khalid Banach, Maciej Bogsrud, Martin P. Bourbon, Mafalda Bruckert, Eric Car, Josip Ceska, Richard Corral, Pablo Descamps, Olivier Dieplinger, Hans Do, Can T. Durst, Ronen Ezhov, Marat V. Fras, Zlatko Gaita, Dan Gaspar, Isabel M. Genest, Jaques Harada-Shiba, Mariko Jiang, Lixin Kayikcioglu, Meral Lam, Carolyn S. P. Latkovskis, Gustavs Laufs, Ulrich Liberopoulos, Evangelos Lin, Jie Lin, Nan Maher, Vincent Majano, Nelson Marais, A. David März, Winfried Mirrakhimov, Erkin Miserez, André R. Mitchenko, Olena Nawawi, Hapizah Nilsson, Lennart Nordestgaard, Børge G. Paragh György (1953-) (belgyógyász) Petrulioniene, Zaneta Pojskic, Belma Reiner, Željko Sahebkar, Amirhossein Santos, Lourdes E. Schunkert, Heribert Shehab, Abdullah Slimane, M. Naceur Stoll, Mario Su, Ta-Chen Susekov, Andrey Tilney, Myra Tomlinson, Brian Tselepis, Alexandros D. Vohnout, Branislav Widén, Elisabeth Yamashita, Shizuya Catapano, Alberico L. Ray, Kausik K.
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