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001-es BibID:	BIBFORM029697
Első szerző:	Blasberg, Ronald
Cím:	Local blood flow in Walker 256 metastatic brain tumors / Blasberg R. G., Shapiro W. R., Molnar P., Patlak C. S., Fenstermacher J. D.
Dátum:	1984
Megjegyzések:	Local blood flow (F) in metastatic Walker 256 (WL-256) brain tumors produced by the intracarotid artery injection of WL-256 tumor cells in rats was measured using 14C-iodoantipyrine and quantitative autoradiography. Blood flow was variable in the tumors; the overall range was 2 to 222 ml hg-1 min-1 and the maximum range in an individual tumor extended over 150 ml hg-1 min-1. Small tumors had mean blood flows similar to surrounding brain. Medium to large tumors had significantly lower flows; the lowest values were usually measured in necrotic or cystic regions, although low values (less than 20 ml hg-1) were also measured in some viable-appearing tumor regions. Blood flow was significantly reduced in brain adjacent to medium and large but not small tumors. A global depression of brain and tumor blood flow was measured in two animals with hydrocephalus and the largest tumor burden. The blood flow patterns of the WL-256 metastatic tumor model are not uniquely different from other brain tumor models although some individual differences exist.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	Journal of Neuro-Oncology. - 2 : 3 (1984), p. 195-204. -
További szerzők:	Shapiro, William R. Molnár Péter Pál (1951-) (pathológus) Patlak, Clifford S. Fenstermacher, Joseph D.
Internet cím:	DOI
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