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001-es BibID:	BIBFORM047531
Első szerző:	Kárai Bettina (orvos)
Cím:	Flow cytometry in the diagnosis of myelodysplastic syndromes / Bettina Kárai, Eszter Szánthó, János Kappelmayer, Zsuzsa Hevessy
Dátum:	2012
Megjegyzések:	Myelodysplastic syndromes are clonal hematopoietic stem cell disorders. Their exact etiology is unknown. Myelodysplasticsyndromes cause progressive bone marrow failure resulting in pancytopenia and refractory, transfusion-dependent anemia.One can observe typical morphological alterations in the erythroid, myeloid and/or megakaryocytic cell lineage. Blast countsmay also be increased. The pathologic cells are genetically unstable, and a myelodysplastic syndrome might transform into acutemyeloid leukemia. The overall survival of these diseases range between few months to around ten years. Correct diagnosis andaccurate prognostic classification is essential. In the past decades several scoring systems were established beginning with theFrench-American-British classification to the most recent Revised International Prognostic Scoring System. In all of theseclassifications bone marrow morphology is still the most important factor, though nowadays the genetic aberrations and flowcytometry findings are also included. The diagnosis and prognostic classification of myelodysplastic syndromes remain a greatchallenge for hematologists.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:	The Electronic Journal Of The International Federation Of Clinical Chemistry And Laboratory Medicine. - 23 : 4 (2012), p. 109-116. -
További szerzők:	Szánthó Eszter (laboratóriumi szakorvos jelölt) Kappelmayer János (1960-) (laboratóriumi szakorvos) Hevessy Zsuzsanna (1966-) (laboratóriumi szakorvos)
Pályázati támogatás:	TAMOP-4.2.2.B-11/1/KONV TÁMOP
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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