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001-es BibID:	BIBFORM053099
Első szerző:	Égerházi Anikó (neurológus, pszichiáter, pszichoterapeuta)
Cím:	Automated Neuropsychological Test Battery in depression - preliminary data / Aniko Egerházi, Petra Balla, Andrea Ritzl, Zsofia Varga, Ede Frecska, Roland Berecz
Dátum:	2013
Megjegyzések:	AIMS:Studies have demonstrated neuropsychological deficits across a variety of cognitive domains in patients with major depressive disorder (MDD) during acute episode. However, limited data are available concerning whether these abnormalities persist in the remission phase.METHODS:In the present study CANTAB (Cambridge Automated Neuropsychological Test Battery) was used to evaluate the cognitive impairment associated with depression during acute episode and in remission. 25 patients with MDD during an acute episode and 11 patients also during remission were tested with CANTAB.RESULTS:During the acute episode, Delayed matching to sample, Paired associate learning, Spatial recognition memory, Rapid visual processing and Visuospatial planning were impaired. In remission the improvement of visual learning ability, spatial recognition memory, psychomotor speed, and executive function was observed.CONCLUSIONS:The results suggest that MDD is associated with neurocognitive dysfunctions in different domains, the most prominent deficit was found in the Paired associate learning test, which requires both the elaboration of "frontal strategies" and the "mnemonic processes". Cognitive impairment was found to improve partly in remission, suggesting that an individual's current mood interacts with the ability to perform a cognitive task. Besides these state markers, trait deficits are important because cognitive impairments which do not improve in remission might serve as endophenotypes of depression.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény hazai lapban cognitive function unipolar depression remission endophenotypes
Megjelenés:	Neuropsychopharmacologia Hungarica. - 15 : 1 (2013), p. 5-11. -
További szerzők:	Balla Petra (1971-) (pszichiáter) Ritzl Andrea Varga Zsófia (1970-) (pszichiáter) Frecska Ede (1953-) (pszichiáter) Berecz Roland (1970-) (pszichiáter szakorvos)
Internet cím:	Intézményi repozitóriumban (DEA) tárolt változat
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