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001-es BibID:	BIBFORM101455
035-os BibID:	(cikkazonosító)970 (WoS)000786981800001 (Scopus)85128843077
Első szerző:	Szegeczki Vince
Cím:	Endometrium as Control of Endometriosis in Experimental Research : assessment of Sample Suitability / Szegeczki Vince, Fazekas László, Kulcsár Máté, Reglodi Dora, Török Péter, Orlik Brigitta, Lagana Antonio Simone, Jakab Attila, Juhasz Tamas
Dátum:	2022
ISSN:	2075-4418
Megjegyzések:	Endometriosis is a chronic gynecological disease that causes numerous severe symptoms in affected women. Revealing alterations of the molecular processes in ectopic endometrial tissue is the current policy for understanding the pathomechanisms and discovering potential novel thera- peutic targets. Examining molecular processes of eutopic endometrium is likely to be a convenient method to compare it with the molecular alterations observed in ectopic tissues. The aim of the present study was to determine what proportion of the surgically resected eutopic endometrial samples is suitable for further experiments so that these can be comparable with endometriosis. Final hospital reports and histopathology reports of a 3-year-long period (1162 cases) were ana- lysed. The application of a retrospective screening method promoted the categorization of these cases, and quantification of the categorized cases was accomplished. In addition, results obtained from cultured endometrium samples were also detailed. Only a small number of the harvested en- dometrial samples was suitable for further molecular analysis, while preoperative screening proto- col could enlarge this fraction. Applying clinical and histopathological selection and exclusion cri- teria for tissue screening and histopathological examination of samples could ensure the compara- bility of healthy endometrium with endometriosis. The present study could be useful for research- ers who intend to perform molecular experiments to compare endometriosis with the physiological processes of the endometrium.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk endometrium curettage hysteroscopy endometrial sampling in vitro endometrial culturing
Megjelenés:	Diagnostics. - 12 : 4 (2022), p. 1-17. -
További szerzők:	Fazekas László Kulcsár Máté Reglődi Dóra (Idegtudományok) Török Péter (1975-) (szülész-nőgyógyász) Orlik Brigitta Laganà, Antonio Simone Jakab Attila (1964-) (szülész-nőgyógyász, endokrinológus) Juhász Tamás (1976-) (biológus, orvosbiológus)
Pályázati támogatás:	ÚNKP-17-2 Egyéb ÚNKP-19-3 Egyéb ÚNKP-20-3-II Egyéb EFOP-3.6.3-VEKOP-16-2017-00009 EFOP NKFIHK139396 Egyéb MTA-TKI 14016 Egyéb
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
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