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001-es BibID:	BIBFORM122079
035-os BibID:	(scopus)85196034108 (wos)001248305800001
Első szerző:	Galofré, Juan C.
Cím:	Treatment of Obesity with Thyroid hormones in Europe. Data from the THESIS* Collaboration / J. C. Galofré, J. J. Díez, R. Attanasio, E. V. Nagy, R. Negro, E. Papini, P. Perros, M. Zarkovic, E. Akarsu, M. Alevizaki, G. Ayvaz, T. Bednarczuk, B. N. Beleslin, E. Berta, M. Bodor, A. M. Borissova, M. Boyanov, C. Buffet, Maria-Cristina Burlacu, H. Dobnig, V. Fadeyev, B. C. T. Field, E. Fliers, D. Führer, T. Hakala, J. Jiskra, P. Kopp, M. Krebs, M. Krsek, M. Kuzma, M. Lantz, I. Lazúrová, L. Leenhardt, V. Luchytskiy, F. M. Puga, A. McGowan, S. Metso, C. Moran, T. Morgunova, D. A. Niculescu, B. Peric, T. Planck, C. Poiana, E. Robenshtok, P. O. Rosselet, M. Ruchala, K. R. Riis, A. Shepelkevich, M. Tronko, D. Unuane, I. Vardarli, W. E. Visser, M. Vryonidou, Y. R. Younes, L. Hegedüs
Dátum:	2025
ISSN:	0391-4097
Megjegyzések:	Purpose The use of thyroid hormones (TH) to treat obesity is unsupported by evidence as refected in international guidelines. We explored views about this practice, and associations with respondent characteristics among European thyroid specialists. Methods Specialists from 28 countries were invited to a survey via professional organisations. The relevant question was whether "Thyroid hormones may be indicated in biochemically euthyroid patients with obesity resistant to lifestyle interventions". Results Of 17,232 invitations 5695 responses were received (33% valid response rate; 65% women; 90% endocrinologists). Of these, 290 (5.1%) stated that TH may be indicated as treatment for obesity in euthyroid patients. This view was commoner among non-endocrinologists (8.7% vs. 4.7%, p<0.01), private practice (6.5% vs. 4.5%, p<0.01), and varied geographically (Eastern Europe, 7.3%; Southern Europe, 4.8%; Western Europe, 2.7%; and Northern Europe, 2.5%). Respondents from Northern and Western Europe were less likely to use TH than those from Eastern Europe (p<0.01). Gross national income (GNI) correlated inversely with this view (OR 0.97, CI: 0.96?0.97; p<0.001). Having national guidelines on hypothyroidism correlated negatively with treating obesity with TH (OR 0.71, CI: 0.55?0.91). Conclusions Despite the lack of evidence, and contrary to guidelines' recommendations, about 5% of respondents stated that TH may be indicated as a treatment for obesity in euthyroid patients resistant to life-style interventions. This opinion was associated with (i) respondent characteristics: being non-endocrinologist, working in private practice, treating a small number of hypothyroid patients annually and (ii) national characteristics: prevalence of obesity, Eastern Europe, low GNI and lack of national hypothyroidism guidelines.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban folyóiratcikk obesity hypothyroidism levothyroxine survey
Megjelenés:	Journal of Endocrinological Investigation. - 48 : 1 (2025), p. 201-212. -
További szerzők:	Díez, Juan J. Attanasio, Roberto Nagy Endre V. (1957-) (belgyógyász, endokrinológus) Negro, Roberto Papini, Enrico Perros, Petros Zarkovic, Milos Akarsu, Ersin Alevizaki, Maria Ayvaz, Goksun Bednarczuk, Tomasz Beleslin, Biljana Nedeljkovic Berta Eszter (1980-) (belgyógyász) Bodor Miklós (1969-) (belgyógyász, endokrinológus) Borissova, Anna-Maria I. Boyanov, Mihail A. Buffet, Camille Burlacu, Maria-Cristina Dobnig, Harald Fadeyev, Valentin Field, Benjamin C. T. Fliers, Eric Führer, Dagmar Hakala, Tommi Jiskra, Jan Kopp, Peter Krebs, Michael Krsek, Michal Kuzma, Martin Lantz, Mikael Lazúrová, Ivica Leenhardt, Laurence Luchytskiy, Vitaliy Puga, Francisca Marques McGowan, Anne Metso, Saara Moran, Carla Morgunova, Tatyana Niculescu, Dan Alexandru Peric, Bozidar Planck, Tereza Poiana, Catalina Robenshtok, Eyal Rosselet, Patrick Ruchaa, Marek Riis, Kamilla Ryom Shepelkevich, Alla P. Tronko, Mykola D. Unuane, David Vardarli, Irfan Visser, W. Edward Vryonidou, M. Younes, Younes Ramazan Hegedüs László
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