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001-es BibID:BIBFORM060588
Első szerző:Jenei Ágnes (fogszakorvos)
Cím:Oral health-related quality of life after prosthetic rehabilitation: a longitudinal study with the OHIP questionnaire / Ágnes Jenei, János Sándor, Csaba Hegedűs, Kinga Bágyi, László Nagy, Csongor Kiss, Gyula Szabó, Ildikó J. Márton
Megjegyzések:Background: Aspects of oral health related quality of life (OHRQoL) attracted an increased attention recently.Objective: The aim of the study was to assess self-reported oral health related quality of life (OHRQoL) amongpatients requiring prosthetic rehabilitation and to determine the rate of improvement 1 month and 6?12 monthsafter therapy. In addition, effect of age, gender, oral health indicators and denture types before treatment wereassessed on OHRQoL as evaluated and reported by the patients.Methods: Hungarian version of OHIP-49 (OHIP-49-H) questionnaire was completed before oral rehabilitation (T0-phase)by 389 patients undergoing prosthetic replacement. After 1 month (T1-phase) and 6?12 months (T2-phase) recallperiods 235 and 92 patients completed the questionnaire. The median interquartile range (IQR) values of the totalOHIP-49-H score were calculated for T0-, T1- and T2-phases. Reliability of the questionnaire was checked by Cronbach'sstatistics. Age, gender, oral health indicators and denture types of patients before and after treatment were recordedand treatment-associated changes in OHRQoL were evaluated.Results: The study demonstrated the excellent reliability and internal consistency of OHIP-49-H by a high andnarrow range of Cronbach's alpha value (0.81-0.93). A median OHIP-49-H score of 52; IQR = 25-83 demonstrated apoor OHRQoL on first admission. Decreasing median total OHIP-49-H scores 1 month (24; IQR = 9-51; p < 0.001)and 6?12 months (20; IQR = 7-37; p = 0,055) after therapy indicated an improvement of OHRQoL. Patients' ageand CPI value assessed before treatment proved to be significant factors of OHRQoL.Conclusions: Here we presented representative data about self-assessed OHRQoL of patients requiring prosthetictreatment from Hungary using OHIP-49-H questionnaire. The results demonstrated that the restoration of oralhealth was associated with an improvement in patients' OHRQoL. According to the demographical and T0 phaseclinical status, the treatment was more effective in the respect of OHIP-49-H score improvement among females(than among males), among younger (than among more aged), and among patients with more serious CPIassessed at T0. The type of prosthetic interventions did not exert a significant effect on total OHIP-49-H score,suggesting that the improvement in OHRQoL is independent from the type of denture applied.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Quality of life
Oral health
Oral Health Impact Profile (OHIP) questionnaire
Megjelenés:Health and Quality of Life Outcomes. - 13 : 99 (2015), p. 1-7. -
További szerzők:Sándor János (1966-) (orvos-epidemiológus) Hegedűs Csaba (1953-) (fogszakorvos) Bágyi Kinga (1971-) (fogszakorvos) Nagy László (1966-) (molekuláris sejtbiológus, biokémikus) Kiss Csongor (1956-) (hematológus, onkológus) Szabó Gyula (orvos) Márton Ildikó (1954-) (fogszakorvos)
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001-es BibID:BIBFORM023539
Első szerző:Márton Ildikó (fogszakorvos)
Cím:The role of reactive oxygen intermediates in the pathogenesis of chronic apical periodontitis / Márton I., Balla G., Hegedűs Cs., Redl P., Szilagyi Z., Karmazsin L., Kiss C.
Megjegyzések:The level of malondialdehyde, a stable end product of lipid peroxidation induced by reactive oxygen intermediates and the activity of two potent antioxidant enzymes, superoxide dismutase and glutathione peroxidase, was investigated in tissue homogenates of 22 surgical periapical granuloma specimens. Malondialdehyde levels were significantly higher and glutathione peroxidase activity was significantly lower in periapical granuloma samples than in healthy gingival tissue homogenates, which were used as controls. The activity of superoxide dismutase was similar in periapical granuloma and in control samples. Our results indicate an altered balance between the production and the elimination of toxic oxygen metabolites in chronic apical periodontitis. We hypothesize that reactive oxygen intermediates, which are being produced by activated phagocytic cells abundantly present in periapical granulomas, can contribute to periapical tissue injury and bone loss in this disease.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
Megjelenés:Oral Microbiology and Immunology 8 : 4 (1993), p. 254-257. -
További szerzők:Balla György (1953-) (csecsemő és gyermekgyógyász, neonatológus) Hegedűs Csaba (1953-) (fogszakorvos) Redl Pál (1953-) (szájsebész) Szilágyi Zoltán (fogorvos) Karmazsin László (1927-2012) (gyermekgyógyász) Kiss Csongor (1956-) (hematológus, onkológus)
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