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001-es BibID:BIBFORM059610
035-os BibID:(Wos)000357327600004 (Scopus)84934444528
Első szerző:Kincse Gyöngyvér (orvos)
Cím:Vitamin D3 levels and bone mineral density in patients with psoriasis and/or psoriatic arthritis / Gyöngyvér Kincse, Pál Harjit Bhattoa, Emese Herédi, József Varga, Andrea Szegedi, Judit Kéri, János Gaál
Dátum:2015
ISSN:0385-2407
Megjegyzések:Limited data are available on the vitamin D3 status and bone mineral density (BMD) of patients with psoriasis orwith psoriatic arthritis. Our study intended to explore possible correlations between vitamin D status and BMD, aswell as among these parameters and the features of the underlying disorder. Seventy-two patients with psoriasis/or psoriatic arthritis (female : male ratio, 40:32; mean age, 58.5 ? 11.6 years; mean duration of follow up,142.7 ? 147.7 months) participated in the study. We evaluated the characteristic clinical features of the underlyingdisease, performed bone densitometry of the lumbar spine and the hip region, measured the serum vitamin 25(OH)D3 levels of the patients, and undertook the statistical analysis of the relationships between the clinical andthe laboratory parameters. The proportion of patients with a low BMD value did not exceed that seen in the generalpopulation. We found an inverse correlation between the serum level of vitamin 25(OH)D3 and body massindex, as well as between the former and the severity of skin involvement. Furthermore, the activity of psoriaticarthritis was significantly higher in patients with inadequate vitamin D3 status. In patients with psoriatic arthritis,BMD significantly exceeded the values measured in patients suffering from psoriatic skin lesions only. Our findingssuggest the importance of evaluating the vitamin D3 status and screening for comorbid conditions in patientswith psoriasis or psoriatic arthritis. This appears justified, in particular, due to the possible role of hypovitaminosisD3 in provoking the development of skin lesions and joint symptoms.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
bone mineral density
D vitamin level
disease activity
Psoriasis
Megjelenés:Journal Of Dermatology. - 42 : 7 (2015), p. 679-684. -
További szerzők:Bhattoa Harjit Pal (1973-) (laboratóriumi szakorvos) Herédi Emese (1979-) (bőrgyógyász) Varga József (1955-) (fizikus) Szegedi Andrea (1964-) (bőrgyógyász) Kéri Judit Gaál János (1965-) (reumatológus, belgyógyász)
Pályázati támogatás:OTKA-K108421
OTKA
TÁMOP-4.2.2.A- 11/1/KONV-2012-0023
TÁMOP
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