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001-es BibID:BIBFORM087867
035-os BibID:(Scopus)85091004594 (WOS)000565252800001
Első szerző:Fülesdi Béla (aneszteziológus)
Cím:Correlation between calcium, water contents and ultrasonographic appearance of atherosclerotic lesions of carotid artery lesions / Béla Fülesdi, Szabolcs Farkas, Zoltán Gyöngyösi, Péter Siró, Dániel Bereczki, József Bacsó, László Csiba
Dátum:2020
ISSN:2081-3856 2081-6936
Megjegyzések:Background We tested the hypothesis whether there is a correlation between the echogenicity and calcium and water contents of carotid plaques. Patients and methods Ninety carotid befurcations from 45 deceased patients were removed during autopsy. Thirty-four plaques were categorized as homogenous echolucent (HEL), homogenous echogenic (HEG) and heterogenous (HE) plaques based on premortem B-mode image. Water content was expressed in % of wet weight. Ca was determined by proton-induced X-ray emission and expressed in ppm. Relative optical density of the B-mode images was analyzed offline using a computer program. Results HEL plaques had lower Ca content (medians and IQRs: 6,145 [4,465?6,536?ppm]) compared to HEG (74,100 [15,300?1,44,500?ppm]), P ? 0.001). HE plaques showed an intermediate calcium content (7,310 [4,840?9,920?ppm]) that was statistically not different from echolucent plaques. Water content of HEG plaques was statistically not different from HEL and HE (HEG:53.5 [35.5?64%], HEL: 73.5 [69.7?78.5%], HE: 70.6 [67.4?73.9%]). HEG plaques had the highest relative optical densities (196 [188?217%]). HEL and HE had similar relative optical densities (HEL: 176 [164?187%], HE: 164 [144?188%], respectively). A significant positive correlation was found between the Ca content and relative optical density of plaques. Conclusions Echogenicity of carotid plaques increases along with their calcium content. Water content may be an important factor in differentiation of different plaques.
Tárgyszavak:Orvostudományok Klinikai orvostudományok idegen nyelvű folyóiratközlemény külföldi lapban
folyóiratcikk
Ca and water contents
carotid plaque
B-mode ultrasound
ultrasonic tissue characterisation
Megjelenés:Translational Neuroscience. - 11 : 1 (2020), p. 269-276. -
További szerzők:Farkas Szabolcs (1983-) (orvos) Gyöngyösi Zoltán (1977-) (aneszteziológus) Siró Péter (1973-) (neurológus, aneszteziológus, intenzív terápiás szakorvos) Bereczki Dániel (1960-) (neurológus) Bacsó József Csiba László (1952-) (neurológus, pszichiáter)
Pályázati támogatás:2017-1.2.1-NKP-2017-00002
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