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001-es BibID:BIBFORM023742
Első szerző:Kalapos István (orvos, élettanász)
Cím:Effect of immobilization on the enzymes of glycogen metabolism / Kalapos I., Szöör A., Vereb G., Bot G., Rapcsák M., Szilágyi T.
Dátum:1983
ISSN:1588-2683
Megjegyzések:Activity of the enzymes regulating glycogen metabolism was determined for glycogen phosphorylase (Ph), phosphorylase kinase (PhK) and glycogen synthetase (GS) in fast extensor digitorum longus (EDL) and slow (soleus) muscles of rats following immobilization by plastering. It was shown that the activity not only of Ph but also of PhK was about 8 times higher in the EDL than in the soleus muscle in correlation with the higher glycogenolytic activity of fast muscles. The activity of GS was approximately similar in the two muscles. PhK activity decreased significantly in the immobilized EDL muscle while in the soleus an early reduction of GS activity ensued. Reduction of the activity of the glycogenolytic enzymes caused dedifferentiation in the muscles with anaerobic metabolism and containing large amounts of glycogenolytic enzymes. The similar rate of Ph and PhK in fast and slow muscles, as well as the similar rate of their reduced activity, during immobilization indicated a close correlation between the two enzymes and raised the possibility of a combined regulation of their turnover.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény hazai lapban
Megjelenés:Acta Physiologica Hungarica. - 62 : 1 (1983), p. 85-91. -
További szerzők:Szöőr Árpád Vereb György (1938-) (biokémikus, sejtbiológus) Bot György (1917-1998) (biokémikus, vegyész) Rapcsák Marianna (1948-) (biológia-kémia szakos tanár) Szilágyi Tibor (1921-2007) (élettanász)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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001-es BibID:BIBFORM023747
Első szerző:Vereb György (biokémikus, sejtbiológus)
Cím:Effect of immobilization on some glycolytic enzymes of skeletal muscle / Vereb G., Bot G., Szücs K., Kovács E., Erdödi F., Kalapos I., Szöör A., Rapcsák M., Szilágyi T.
Dátum:1984
ISSN:1588-2683
Megjegyzések:The effect of immobilization by plaster cast was studied on the activities of phosphoglucomutase (PGM), pyruvate kinase ( PyK ) and cAMP-dependent protein kinase in fast (extensor digitorum longus [EDL]), and slow (soleus) muscles of rats. In control untreated animals, PGM and PyK activities are 3 and 5 fold higher respectively in EDL than in soleus in correlation with the high glycolytic activity of fast muscles. During the four weeks period of immobilization a 20% decrease occurred in PGM activity, to which no limiting role in glycolysis is attributed, while PyK which has a regulatory function, showed a 35% decrease in EDL; at the same time in the soleus the activity of these enzymes did not change. The decrease of PGM and PyK activity in EDL diminished the difference between the slow and fast muscles, and it was evaluated as a tendency to dedifferentiation (transformation). The activity of cAMP-dependent protein kinase, in contrast to the glycolytic enzymes, was higher in the soleus than in the EDL and during immobilization it did not change significantly in either the muscles.
Tárgyszavak:Orvostudományok Elméleti orvostudományok idegen nyelvű folyóiratközlemény hazai lapban
Megjelenés:Acta Physiologica Hungarica. - 63 : 1 (1984), p. 55-61. -
További szerzők:Bot György (1917-1998) (biokémikus, vegyész) Szűcs Kornélia (1945-) (biokémikus) Kovács E. Erdődi Ferenc (1953-) (biokémikus) Kalapos István (1954-) (orvos, élettanász) Szöőr Árpád Rapcsák Marianna (1948-) (biológia-kémia szakos tanár) Szilágyi Tibor (1921-2007) (élettanász)
Internet cím:Intézményi repozitóriumban (DEA) tárolt változat
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