Találati lista | Tudóstér

001-es BibID:	BIBFORM122697
035-os BibID:	(Scopus)85199038533
Első szerző:	Hashmi, Amna (orvostanhallgató)
Cím:	Relevance of Proteinuria in Kidney Transplant Recipients and Allograft Outcomes / Amna Jousaf Hashmi, Boglárka Bujáki, László Bidiga, László Kardos, József Balla, Réka P. Szabó
Dátum:	2024
ISSN:	0041-1345
Megjegyzések:	Introduction: The onset of proteinuria in renal allograft recipients is frequently associated with an increased risk for both graft failure and mortality. We investigated the risk associated with post-transplant proteinuria and its time-dynamics in a select group treated for biopsy proven antibody-mediated rejection (ABMR). Methods: Eighty-five transplanted patients were enrolled in our study and followed up from transplantation until 31 October 2020, death, or date of return to dialysis. We created 2 main groups: the ABMR group (n=19) and an ABMR-negative control group with stable kidney function (n=52) without DSA and a subgroup with DSA but stable graft function (n=14) without ABMR. Differences in patient, donor, and transplant graft characteristics between the groups were assessed by Fisher's exact test for categorical variables. Death-censored graft loss was evaluated with the help of Kaplan-Meier analysis using log risk statistics. Results: Proteinuria decreased after treatment in the ABMR group (p<0.0009). Pre-treatment every 10 mg/mmol increase in proteinuria was associated with a 7% increase in the risk for graft failure in ABMR group. Estimated 3-year graft survival was 87.5% in the ABMR group, compared to 93% in the group without ABMR but with preformed DSA, and 100 % in the DSA negative subgroup (log-rank probe p<0.0666).
Tárgyszavak:	Orvostudományok Klinikai orvostudományok esettanulmány folyóiratcikk proteinuria donor specific antibody graft outcome
Megjelenés:	Transplantation Proceedings. - 56 : 6 (2024), p. 1273-1279. -
További szerzők:	Bujáki Boglárka (1992-) (biomérnök hallgató) Bidiga László (1977-) (patológus) Kardos László (1970-) (megelőző orvostan és népegészségtan szakorvos) Balla József (1959-) (belgyógyász, nephrológus) P. Szabó Réka (1979-) (belgyógyász, nephrológus)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:

001-es BibID:	BIBFORM107406
Első szerző:	Hashmi, Amna (orvostanhallgató)
Cím:	Recurrent Iga Nephropathy in A Kidney Transplant Patient : a Case Report / Amna Jousaf Hashmi, László Bidiga, Csilla Markóth, Ibolya File, József Balla, Réka P. Szabó
Dátum:	2023
Megjegyzések:	There are no universally accepted guidelines for the treatment of recurrent IgA nephropathy. The clinical course of this condition is variable due to the fact that it can be diagnosed in asymptomatic patients on a protocol biopsy, in patients with mild hematuria or proteinuria, or in patients with a rapidly deteriorating kidney function. Our aim was to present the case of a kidney transplant patient with biopsy proven IgA nephropathy. Our findings show that glomerular filtration pressure can be successfully decreased with combined antihypertensive treatment and SGLT2 inhibitor treatment. Refill with personalized immunosuppressive regimen helped us achieve partial remission.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok esettanulmány folyóiratcikk Kidney transplantation Recurrent IgA nephropathy SGLT2-inhibitor
Megjelenés:	Journal of Urology and Renal Diseases. - 8 : 1 (2023), p. 1-4. -
További szerzők:	Bidiga László (1977-) (patológus) Markóth Csilla (1984-) (belgyógyász, nephrológus) Kuszkáné File Ibolya (1983-) (orvos) Balla József (1959-) (belgyógyász, nephrológus) P. Szabó Réka (1979-) (belgyógyász, nephrológus)
Internet cím:	DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon:

001-es BibID:	BIBFORM102226
Első szerző:	Hashmi, Amna (orvostanhallgató)
Cím:	Relevance of Proteinuria and Donor Specific Antibody in Kidney Transplanted Recipients and Allograft Outcomes / Amna Hashmi, Nóra Klenk, László Bidiga, László Kardos, Balázs Áron Nemes, József Balla, Réka P. Szabó
Dátum:	2022
ISSN:	0931-0509
Megjegyzések:	BACKGROUND AND AIMS The onset of proteinuria in renal allograft recipients is a frequent complication that may be associated with an increased risk of graft failure and mortality. Our aim was to research if proteinuria effects is independent from donor specific antibody (DSA) for transplant graft survival and the changes of proteinuria response to therapy in ABMR group. METHOD 85 transplanted patients were enrolled in our study and followed up till 31 October 2020 or till death, or date of return to dialysis. We created three groups: ABMR group (n = 19, biopsy proven antibody mediated rejection), ABMRDSApos positive group (n = 14) ABMRDSAneg (n = 5), DSA negative group with stabile kidney function without rejection as a reference (n = 52). Differences in patient, donor and transplant characteristics between DSA positive and negative groups were assessed by Fishers exact test for categorical variables. Death censored graft loss was assessed by Kaplan Meier analysis with log risk statistics. RESULTS Proteinuria decrease after treatment in ABMR group (P = 0.0009). Graft failure's frequency increase every 10 mg/mmol elevation of proteinuria means 7% elevation (hazard ratio: 1.07%). Before treatment nephrotic proteinuria was found in group AMBRDSApoz 21%, 14,29% in group ABMR DSAneg 1,92% in reference group. Estimated 3-year graft survival was 87, 5% in ABMR group, 93% in DSA pos group, and 100% in DSA negative group (log-rank probe P = 0.0666). CONCLUSION The presence of DSA increases graft loss but it is independent to proteinuria. Therapy refractory proteinuria state represents worse graft survival.
Tárgyszavak:	Orvostudományok Klinikai orvostudományok idézhető absztrakt folyóiratcikk
Megjelenés:	Nephrology Dialysis Transplantation. - 37 : 3 (2022), p. i689. -
További szerzők:	Klenk Nóra (1967-) (belgyógyász, nefrológus) Bidiga László (1977-) (patológus) Kardos László (1970-) (megelőző orvostan és népegészségtan szakorvos) Nemes Balázs Áron (1969-) (sebész) Balla József (1959-) (belgyógyász, nephrológus) P. Szabó Réka (1979-) (belgyógyász, nephrológus)
Internet cím:	Szerző által megadott URL DOI Intézményi repozitóriumban (DEA) tárolt változat
Borító:
Saját polcon: